Botanical species · safety record

Polygonatum sibiricum

The EFSA Compendium of Botanicals holds 11 constituent measurements and 4 adverse-effect records for Polygonatum sibiricum. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Polygonatum sibiricum F.Delaroche

11Constituent measurements

4Safety records

8Cited sources

61Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 61 licensed products naming Polygonatum sibiricum as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Source material stated

Rhizoma
Rhizome
Rhizome (stir-baked with wine)
Root
Stolons

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Alkaloids	Roots and other underground parts	Solvent extraction	—	GC-MS	Resolve DOI
Imidazole alkaloids	Roots and other underground parts	Solvent extraction	5.39 Milligram/gram	GC-MS	Resolve DOI
Steroidal furostan saponins	Roots and other underground parts	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	Resolve DOI
Steroidal saponins	Roots and other underground parts	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	Resolve DOI
Triterpene saponins	Roots and other underground parts	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	Resolve DOI
Anthraquinones	Unspecified	Solvent extraction	—	Unspecified	No resolvable identifier
Isoflavones	Roots and other underground parts	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Liriodendrin	Roots and other underground parts	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Saponins	Roots and other underground parts	Solvent extraction	1.57 Percent	Unspecified	No resolvable identifier
Saponins	Stem / stalk	Solvent extraction	1.57 Percent	Unspecified	No resolvable identifier
Syringaresinol	Roots and other underground parts	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Digestive	Digestive	Roots and other underground parts	Solvent extraction	—	In vitro	No resolvable identifier
Digestive	Digestive	Stem / stalk	Solvent extraction	—	In vitro	No resolvable identifier
Digestive	Digestive	Stem / stalk	—	—	In vitro	No resolvable identifier
Digestive	Digestive	Roots and other underground parts	—	—	In vitro	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Dong, Li., Ni, Jing man. Preliminary study of an alpha-glucosidase inhibitor from the roots and stems of Polygonatum sibiricum Red. Asian journal of traditional medicines, 2008, p. 179-185.
Sun, LR., Li, X., Wang, SX. Two new alkaloids from the rhizome of Polygonatum sibiricum. Journal of asian natural products research, 2005, vol. 7, no. 2, p. 127-130. DOI
Sun, Longru., Li, Xian. Studies on chemical constituents of rhizome of Polygonatum sibiricum (II). Zhongcaoyao, 2001, p. 586-588.
Li, Ying., Zhao, Bing., Chen, Qian-liang., Ni, Shi-feng. Determination and comparison on the content of total saponins of Polygonatum sibiricun Red. and its callus. Beifang yuanyi, 2011, p. 167-168.
Baek, Seung-Hoon., Lee, Jin Gyun., Park, Seo Young., Piao, Xiang-Lan., Kim, Hyun Young., Bae, Ok-Nam., Park, Jeong Hill. Gas chromatographic determination of azetidine-2-carboxylic acid in rhizomes of Polygonatum sibiricum and Polygonatum odoratum. JOURNAL OF FOOD COMPOSITION AND ANALYSIS, 2012, vol. 25, no. 2, p. 137-141. DOI
Ahn, MJ., Kim, CY., Yoon, KD., Ryu, MY., Cheong, JH., Chin, YW., Kim, J. Steroidal saponins from the rhizomes of Polygonatum sibiricum. JOURNAL OF NATURAL PRODUCTS, 2006, vol. 69, no. 3, p. 360-364. DOI
Xu, De-Ping., Hu, Chang-Ying., Zhang, Yang. Two new steroidal saponins from the rhizome of Polygonatum sibiricum. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2009, vol. 11, no. 1, p. 1-6. DOI
Hu, Chang-Ying., Xu, De-Ping., Wu, Yu-Mei., Ou, Shi-Yi. Triterpenoid saponins from the rhizome of Polygonatum sibiricum. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2010, vol. 12, no. 9, p. 801-808. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature