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Botanical species · safety record

Polypodium vulgare

The EFSA Compendium of Botanicals holds 6 constituent measurements for Polypodium vulgare. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Polypodium vulgare L.

6Constituent measurements
0Safety records
5Cited sources
15Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 15 licensed products naming Polypodium vulgare as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

  • Dry

Source material stated

  • Rhizome
  • Root
  • Root and Rhizome
  • Root and rhizome

What the records describe

Constituents measured

  • Glycyrrhizic acid2
  • Saponins2
  • Epoxides1
  • Salicylic acid1

Plant parts

  • Roots and other underground parts3
  • Unspecified2
  • Leaves1

Preparations

  • Solvent extraction6

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
SaponinsRoots and other underground partsSolvent extraction—Nuclear Magnetic Resonance (NMR)Resolve DOI
EpoxidesUnspecifiedSolvent extraction—Nuclear Magnetic Resonance (NMR)No resolvable identifier
Glycyrrhizic acidRoots and other underground partsSolvent extraction≥ 2 PercentUnspecifiedNo resolvable identifier
Glycyrrhizic acidRoots and other underground partsSolvent extraction≤ 20 PercentUnspecifiedNo resolvable identifier
Salicylic acidLeavesSolvent extraction—Colorimetry, Spectroscopy (Spectrometry) and PhotometryNo resolvable identifier
SaponinsUnspecifiedSolvent extraction—UnspecifiedNo resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Constantinescu, E., Palade, M., Panait, I. Chemical studies on rhizoma polypodii. Pharmazie, 1966.
  2. Wishart, DS., Jewison, T., Guo, AC., Wilson, M., Knox, C., Liu, Y., Djoumbou, Y., Mandal, R., Aziat, F., Dong, E., Bouatra, S., Sinelnikov, I., Arndt, D., Xia, J., Liu, P., Yallou, F., Bjorndahl, T., Perez-Pineiro, R., Eisner, R., Allen, F., Neveu, V., Greiner, R., Scalbert, A. Polypodosaponin (HMDB34337).. Human metabolome database, 2012, vol. 3.0.
  3. YAMADA, H., NISHIZAWA, M. SYNTHESIS AND STRUCTURE REVISION OF INTENSELY SWEET SAPONIN OSLADIN. JOURNAL OF ORGANIC CHEMISTRY, 1995, vol. 60, no. 2, p. 386-397. DOI
  4. Berti, Giancarlo. Triterpenoids from ferns. Corsi e seminari di chimica, consiglio nazionale delle ricerche e fondazione f. giordani, 1968, p. 65-67.
  5. Fischer, Louis., Lynn, E. V. Licorice fern and wild licorice as substitutes for licorice. Journal of the American Pharmaceutical Association, None, p. 1225-1230.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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