Botanical species · safety record

Prunus africana

The EFSA Compendium of Botanicals holds 4 constituent measurements and 3 adverse-effect records for Prunus africana. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Prunus africana (Hook.f.) Kalkman

4Constituent measurements

3Safety records

7Cited sources

233Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 233 licensed products naming Prunus africana as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Dry
Extract Type TBA

Source material stated

Aged bark
Bark
Bark (trunk)
Bark and buds
Bark extract
Branch bark
New material
Prunus africana

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Proanthocyanidins (condensed tannins)	Leaves	Solvent extraction	78.1 Percent	Element spectroscopy	Resolve DOI
Cyanogenic glycosides	Unspecified	—	—	Unspecified	No resolvable identifier
Lignans	Bark	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	No resolvable identifier
Saponins	Live plants	Solvent extraction	—	IR and Raman Spectroscopy	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Systemic	—	Bark	Solvent extraction	House mouse (as animal)	Acute toxicity	Resolve DOI
Systemic	Cardiovascular / haematological	Bark	Solvent extraction	Rat (as animal)	Short-term toxicity	Resolve DOI
Hemopoietic	Cardiovascular / haematological	Bark	Solvent extraction	Rat (as animal)	Subchronic	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Chapman, CA., Chapman, LJ. Foraging challenges of red colobus monkeys: influence of nutrients and secondary compounds . Comparative biochemistry and physiology a-molecular and integrative physiology, 2002, vol. 133, no. 3, p. 861-875.
Kareru, P. G., Keriko, J. M., Gachanja, A. N., Kenji, G. M. Direct detection of triterpenoid saponins in medicinal plants. African Journal of Traditional, Complementary and Alternative Medicines, 2008, p. 56-60.
Fashing, Peter J., Dierenfeld, Ellen S., Mowry, Christopher B. Influence of plant and soil chemistry on food selection, ranging patterns, and biomass of Colobus guereza in Kakamega Forest, Kenya. INTERNATIONAL JOURNAL OF PRIMATOLOGY, 2007, vol. 28, no. 3, p. 673-703. DOI
Nieri, E., Bilia, A. R., Morelli, I. New lignans from Prunus africana Hook. Rivista italiana eppos, 1996, p. 27-31.
Karani, L. W., Tolo, F. M., Karanja, S. M., Khayeka-Wandabwa, C. Safety of Prunus africana and Warburgia ugandensis in asthma treatment. South african journal of botany, 2013, vol. 88, p. 183-190. DOI
Gathumbi, PK., Mwangi, JW., Njiro, SM., Mugera, GM. Biochemical and haematological changes in rats administered an aqueous extract of Prunus africana stem-bark at various dosage levels. ONDERSTEPOORT JOURNAL OF VETERINARY RESEARCH, 2000, vol. 67, no. 2, p. 123-128.
Gathumbi, PK., Mwangi, JW., Mugera, GM., Njiro, SM. Toxicity of chloroform extract of Prunus africana stem bark in rats: Gross and histological lesions . Phytotherapy research, 2002, vol. 16, no. 3, p. 244-247. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature