Botanical species · safety record

Prunus armeniaca

The EFSA Compendium of Botanicals holds 17 constituent measurements, 1 adverse-effect record and 1 genotoxicity assay for Prunus armeniaca. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Prunus armeniaca L.

17Constituent measurements
2Safety records
9Cited sources
596Licensed products (Canada)

Also recorded as

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 596 licensed products naming Prunus armeniaca as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

  • Dry
  • Extract Type TBA
  • Fresh

Source material stated

  • Dried ripe seeds
  • Fruit
  • Fruit concentrate
  • Fruit extract
  • Fruits
  • Husk
  • Kernel
  • New material

What the records describe

Constituents measured

  • Cyanide3
  • Cyanogenic glycosides2
  • Acetaldehyde1
  • Alkaloids1
  • Daidzein1
  • Hydrocyanic acid1
  • Lariciresinol1
  • Lignans1
  • Lignans, total1
  • Nitrates1

Plant parts

  • Seed10
  • Fruit unspecified8

Preparations

  • Solvent extraction8
  • Essential oil1

Effect types

  • Pulmonary and cardiac1

Target tissues

  • Cardiovascular1
  • haematological1

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
AlkaloidsSeed0.61 Milligram/100 gramUnspecifiedResolve DOI
CyanideSeedEssential oil1.67 Milligram/kilogramElement spectroscopyResolve DOI
Cyanogenic glycosidesSeed≤ 6.35 Gram/100 gramUnspecifiedResolve DOI
Cyanogenic glycosidesSeed≥ 4.41 Gram/100 gramUnspecifiedResolve DOI
Hydrocyanic acidSeed136.85 Milligram/100 gramUnspecifiedResolve DOI
SaponinsSeed2.14 Gram/100 gramUnspecifiedResolve DOI
TanninsSeed159.67 Milligram/100 gramUnspecifiedResolve DOI
AcetaldehydeFruit unspecifiedSolvent extraction1.57 Milligram/kilogramGaschromatography (GC)No resolvable identifier
CyanideSeedSolvent extraction≤ 2259.81 Microgram/gramChromatographic testsNo resolvable identifier
CyanideSeedSolvent extraction≥ 6.42 Microgram/gramChromatographic testsNo resolvable identifier
DaidzeinFruit unspecifiedSolvent extraction50 Microgram/gramGC-MSNo resolvable identifier
LariciresinolFruit unspecifiedSolvent extraction105 Microgram/100 gramLC-MSNo resolvable identifier
LignansFruit unspecifiedSolvent extraction31 Microgram/100 gramLC-MSNo resolvable identifier
Lignans, totalFruit unspecifiedSolvent extraction450 Microgram/100 gramLC-MSNo resolvable identifier
NitratesFruit unspecified0.00648 Milligram/gramUnspecifiedNo resolvable identifier
NitritesFruit unspecified0.1609 Nanogram/gramUnspecifiedNo resolvable identifier
PinoresinolFruit unspecifiedSolvent extraction314 Microgram/100 gramLC-MSNo resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

EffectTarget tissuePlant partPreparationTest organismTest typeSource
Pulmonary and cardiacCardiovascular / haematologicalSeedHuman (as organism)Case reportResolve DOI

Genotoxicity testing

Outcomes of genotoxicity assays as recorded in the source. A negative assay is a result under those test conditions, not a clearance.

OutcomeEndpointTestTested organismMetabolic activationSource
Positivechromosome aberrationsingle cell gel/comet assay in mammalian cells for detection of DNA damageOtherNo resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Tanwar, Beenu., Modgil, Rajni., Goyal, Ankit. Antinutritional factors and hypocholesterolemic effect of wild apricot kernel (Prunus armeniaca L.) as affected by detoxification. Food & function, 2018, vol. 9, no. 4, p. 2121-2135. DOI
  2. Griesenbeck, John S., Steck, Michelle D., Huber, John C., Jr., Sharkey, Joseph R., Rene, Antonio A., Brender, Jean D. Development of estimates of dietary nitrates, nitrites, and nitrosamines for use with the short willet food frequency questionnaire. Nutrition journal, 2009, vol. 8, p. No pp. given.
  3. Milder, Ivon E. J., Arts, Ilja C. W., van de Putte, Betty., Venema, Dini P., Hollman, Peter C. H. Lignan contents of Dutch plant foods: A database including lariciresinol, pinoresinol, secoisolariciresinol and matairesinol. British journal of nutrition, 2005, vol. 93, no. 3, p. 393-402.
  4. Liggins, J., Bluck, L. J. C., Runswick, S., Atkinson, C., Coward, W. A., Bingham, S. A. Daidzein and genistein content of fruits and nuts. Journal of nutritional biochemistry, 2000, vol. 11, no. 6, p. 326-331.
  5. Karatepe, Rukiye., Akal, Zeynep Ulker., Alpsoy, Lokman. GENOTOXIC AND CYTOTOXIC EFFECTS OF PRUNUS ARMENIACA SEED EXTRACT IN VITRO. Fresenius environmental bulletin, 2015, vol. 24, no. 8, p. 2549-2555.
  6. Konstantatos, Alex., Shiv Kumar, Malini., Burrell, Aidan., Smith, Joel. An unusual presentation of chronic cyanide toxicity from self-prescribed apricot kernel extract.. Bmj case reports, 2017, vol. 2017. DOI
  7. Miao, Xingjun., Zhao, Zhong., Li, Hongjiao., Li, Ming., Zhu, Hailan. Acute toxicity of refined wild apricot oil in rats. Scienceasia, 2014, vol. 40, no. 5, p. 323-326. DOI
  8. Cho, Hye-Jeon., Do, Byung-Kyung., Shim, Soon-Mi., Kwon, Hoonjeong., Lee, Dong-Ha., Nah, Ahn-Hee., Choi, Youn-Ju., Lee, Sook-Yeon. Determination of cyanogenic compunds in edible plants by ion chromatography. Toxicological research (seoul, republic of korea), 2013, vol. 29, no. 2, p. 143-147.
  9. Uebelacker, Michael., Lachenmeier, Dirk W. Quantitative determination of acetaldehyde in foods using automated digestion with simulated gastric fluid followed by headspace gas chromatography. Journal of analytical methods in chemistry, 2011, vol. 907317, p. 13 pp.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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