Botanical species · safety record
Prunus armeniaca
The EFSA Compendium of Botanicals holds 17 constituent measurements, 1 adverse-effect record and 1 genotoxicity assay for Prunus armeniaca. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Prunus armeniaca L.
Also recorded as
Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.
Regulatory presence
Health Canada's Licensed Natural Health Products Database holds 596 licensed products naming Prunus armeniaca as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.
Extract types on licence
Source material stated
What the records describe
Constituents measured
- Cyanide3
- Cyanogenic glycosides2
- Acetaldehyde1
- Alkaloids1
- Daidzein1
- Hydrocyanic acid1
- Lariciresinol1
- Lignans1
- Lignans, total1
- Nitrates1
Plant parts
- Seed10
- Fruit unspecified8
Preparations
- Solvent extraction8
- Essential oil1
Effect types
- Pulmonary and cardiac1
Target tissues
- Cardiovascular1
- haematological1
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Alkaloids | Seed | — | 0.61 Milligram/100 gram | Unspecified | Resolve DOI |
| Cyanide | Seed | Essential oil | 1.67 Milligram/kilogram | Element spectroscopy | Resolve DOI |
| Cyanogenic glycosides | Seed | — | ≤ 6.35 Gram/100 gram | Unspecified | Resolve DOI |
| Cyanogenic glycosides | Seed | — | ≥ 4.41 Gram/100 gram | Unspecified | Resolve DOI |
| Hydrocyanic acid | Seed | — | 136.85 Milligram/100 gram | Unspecified | Resolve DOI |
| Saponins | Seed | — | 2.14 Gram/100 gram | Unspecified | Resolve DOI |
| Tannins | Seed | — | 159.67 Milligram/100 gram | Unspecified | Resolve DOI |
| Acetaldehyde | Fruit unspecified | Solvent extraction | 1.57 Milligram/kilogram | Gaschromatography (GC) | No resolvable identifier |
| Cyanide | Seed | Solvent extraction | ≤ 2259.81 Microgram/gram | Chromatographic tests | No resolvable identifier |
| Cyanide | Seed | Solvent extraction | ≥ 6.42 Microgram/gram | Chromatographic tests | No resolvable identifier |
| Daidzein | Fruit unspecified | Solvent extraction | 50 Microgram/gram | GC-MS | No resolvable identifier |
| Lariciresinol | Fruit unspecified | Solvent extraction | 105 Microgram/100 gram | LC-MS | No resolvable identifier |
| Lignans | Fruit unspecified | Solvent extraction | 31 Microgram/100 gram | LC-MS | No resolvable identifier |
| Lignans, total | Fruit unspecified | Solvent extraction | 450 Microgram/100 gram | LC-MS | No resolvable identifier |
| Nitrates | Fruit unspecified | — | 0.00648 Milligram/gram | Unspecified | No resolvable identifier |
| Nitrites | Fruit unspecified | — | 0.1609 Nanogram/gram | Unspecified | No resolvable identifier |
| Pinoresinol | Fruit unspecified | Solvent extraction | 314 Microgram/100 gram | LC-MS | No resolvable identifier |
Recorded adverse effects
Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.
| Effect | Target tissue | Plant part | Preparation | Test organism | Test type | Source |
|---|---|---|---|---|---|---|
| Pulmonary and cardiac | Cardiovascular / haematological | Seed | — | Human (as organism) | Case report | Resolve DOI |
Genotoxicity testing
Outcomes of genotoxicity assays as recorded in the source. A negative assay is a result under those test conditions, not a clearance.
| Outcome | Endpoint | Test | Tested organism | Metabolic activation | Source |
|---|---|---|---|---|---|
| Positive | chromosome aberration | single cell gel/comet assay in mammalian cells for detection of DNA damage | Other | — | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Tanwar, Beenu., Modgil, Rajni., Goyal, Ankit. Antinutritional factors and hypocholesterolemic effect of wild apricot kernel (Prunus armeniaca L.) as affected by detoxification. Food & function, 2018, vol. 9, no. 4, p. 2121-2135. DOI
- Griesenbeck, John S., Steck, Michelle D., Huber, John C., Jr., Sharkey, Joseph R., Rene, Antonio A., Brender, Jean D. Development of estimates of dietary nitrates, nitrites, and nitrosamines for use with the short willet food frequency questionnaire. Nutrition journal, 2009, vol. 8, p. No pp. given.
- Milder, Ivon E. J., Arts, Ilja C. W., van de Putte, Betty., Venema, Dini P., Hollman, Peter C. H. Lignan contents of Dutch plant foods: A database including lariciresinol, pinoresinol, secoisolariciresinol and matairesinol. British journal of nutrition, 2005, vol. 93, no. 3, p. 393-402.
- Liggins, J., Bluck, L. J. C., Runswick, S., Atkinson, C., Coward, W. A., Bingham, S. A. Daidzein and genistein content of fruits and nuts. Journal of nutritional biochemistry, 2000, vol. 11, no. 6, p. 326-331.
- Karatepe, Rukiye., Akal, Zeynep Ulker., Alpsoy, Lokman. GENOTOXIC AND CYTOTOXIC EFFECTS OF PRUNUS ARMENIACA SEED EXTRACT IN VITRO. Fresenius environmental bulletin, 2015, vol. 24, no. 8, p. 2549-2555.
- Konstantatos, Alex., Shiv Kumar, Malini., Burrell, Aidan., Smith, Joel. An unusual presentation of chronic cyanide toxicity from self-prescribed apricot kernel extract.. Bmj case reports, 2017, vol. 2017. DOI
- Miao, Xingjun., Zhao, Zhong., Li, Hongjiao., Li, Ming., Zhu, Hailan. Acute toxicity of refined wild apricot oil in rats. Scienceasia, 2014, vol. 40, no. 5, p. 323-326. DOI
- Cho, Hye-Jeon., Do, Byung-Kyung., Shim, Soon-Mi., Kwon, Hoonjeong., Lee, Dong-Ha., Nah, Ahn-Hee., Choi, Youn-Ju., Lee, Sook-Yeon. Determination of cyanogenic compunds in edible plants by ion chromatography. Toxicological research (seoul, republic of korea), 2013, vol. 29, no. 2, p. 143-147.
- Uebelacker, Michael., Lachenmeier, Dirk W. Quantitative determination of acetaldehyde in foods using automated digestion with simulated gastric fluid followed by headspace gas chromatography. Journal of analytical methods in chemistry, 2011, vol. 907317, p. 13 pp.
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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