Botanical species · safety record

Quassia amara

The EFSA Compendium of Botanicals holds 2 constituent measurements and 4 adverse-effect records for Quassia amara. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Quassia amara L.

2Constituent measurements
4Safety records
4Cited sources
32Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 32 licensed products naming Quassia amara as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

  • Dry
  • Fresh

Source material stated

  • Aged bark
  • Bark
  • Inner bark of roots
  • Stem bark
  • Wood
  • Wood of branches
  • Wood of stems

What the records describe

Constituents measured

  • Alkaloids1
  • Carboline alkaloids1

Plant parts

  • Wood4
  • Bark2

Preparations

  • Solvent extraction6

Effect types

  • Reproductive4

Target tissues

  • Testes2
  • Urogenital: ovaries2

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
AlkaloidsWoodSolvent extractionNuclear Magnetic Resonance (NMR)Resolve DOI
Carboline alkaloidsWoodSolvent extractionChromatography hyphenated to element spectrometryResolve DOI

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

EffectTarget tissuePlant partPreparationTest organismTest typeSource
ReproductiveTestesWoodSolvent extractionRat (as animal)Reproduction toxicityResolve DOI
ReproductiveTestesWoodSolvent extractionRat (as animal)Reproduction toxicityResolve DOI
ReproductiveUrogenital: ovariesBarkSolvent extractionRat (as animal)Reproduction toxicityNo resolvable identifier
ReproductiveUrogenital: ovariesBarkSolvent extractionRat (as animal)Reproduction toxicityNo resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Barbetti, P., Grandolini, G., Fardella, G., Chiappini, I. Indole Alkaloids from Quassia amara.. Planta medica, 1987, vol. 53, no. 3, p. 289-90. DOI
  2. Raji, Yinusa., Akinola, Adeniran., Oyeyipo, Ibukun P., Femi-Akinlosotu, Omowunmi. Reproductive activities of female albino rats treated with quassin, a bioactive triterpenoid from stem bark extract of Quassia amara.. Physiological Society of Nigeria, 2010, vol. 25, no. 2, p. 95-102.
  3. Raji, Y., Bolarinwa, AF. Antifertility activity of Quassia amara in male rats - In vivo study. LIFE SCIENCES, 1997, vol. 61, no. 11, p. 1067-1074. DOI
  4. NJAR, VCO., ALAO, TO., OKOGUN, JI., HOLLAND, HL. 2-METHOXYCANTHIN-6-ONE - A NEW ALKALOID FROM THE STEM WOOD OF QUASSIA-AMARA. PLANTA MEDICA, 1993, vol. 59, no. 3, p. 259-261. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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