Botanical species · safety record
Rollinia mucosa
The EFSA Compendium of Botanicals holds 29 constituent measurements for Rollinia mucosa. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Rollinia mucosa (Jacq.) Baill.
Also recorded as
Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.
Regulatory presence
No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.
What the records describe
Constituents measured
- Acetogenins9
- Aporphine alkaloids4
- Lignans3
- (+)-epieudesmine2
- Alkaloids2
- Epi-magnolin a2
- Yangambin2
- Annonacin1
- Anonaine1
- Asiminacin1
Plant parts
- Leaves12
- Bark5
- Fruit unspecified5
- Seed3
- Fruit peel1
- Live plants1
- Stem1
- Unspecified1
- stalk1
Preparations
- Solvent extraction29
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Acetogenins | Leaves | Solvent extraction | — | Unspecified | Resolve DOI |
| Acetogenins | Bark | Solvent extraction | — | LC-MS | Resolve DOI |
| Acetogenins | Seed | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Acetogenins | Leaves | Solvent extraction | — | Colorimetry, Spectroscopy (Spectrometry) and Photometry | Resolve DOI |
| Acetogenins | Fruit unspecified | Solvent extraction | — | Colorimetry, Spectroscopy (Spectrometry) and Photometry | Resolve DOI |
| Acetogenins | Seed | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Acetogenins | Leaves | Solvent extraction | — | LC-MS | Resolve DOI |
| Acetogenins | Leaves | Solvent extraction | — | LC-MS | Resolve DOI |
| Aporphine alkaloids | Fruit unspecified | Solvent extraction | — | Colorimetry, Spectroscopy (Spectrometry) and Photometry | Resolve DOI |
| Aporphine alkaloids | Stem / stalk | Solvent extraction | — | Colorimetry, Spectroscopy (Spectrometry) and Photometry | Resolve DOI |
| Isoquinoline alkaloids | Fruit unspecified | Solvent extraction | — | Colorimetry, Spectroscopy (Spectrometry) and Photometry | Resolve DOI |
| Lignans | Seed | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Lignans | Fruit unspecified | Solvent extraction | — | Colorimetry, Spectroscopy (Spectrometry) and Photometry | Resolve DOI |
| (+)-epieudesmine | Leaves | Solvent extraction | ≥ 0.05 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | No resolvable identifier |
| (+)-epieudesmine | Leaves | Solvent extraction | ≤ 0.63 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | No resolvable identifier |
| Acetogenins | Leaves | Solvent extraction | — | Unspecified | No resolvable identifier |
| Alkaloids | Live plants | Solvent extraction | — | — | No resolvable identifier |
| Alkaloids | Bark | Solvent extraction | — | Colorimetry, Spectroscopy (Spectrometry) and Photometry | No resolvable identifier |
| Annonacin | Fruit unspecified | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | No resolvable identifier |
| Anonaine | Bark | Solvent extraction | — | Colorimetry, Spectroscopy (Spectrometry) and Photometry | No resolvable identifier |
| Aporphine alkaloids | Bark | Solvent extraction | — | Colorimetry, Spectroscopy (Spectrometry) and Photometry | No resolvable identifier |
| Aporphine alkaloids | Unspecified | Solvent extraction | — | Unspecified | No resolvable identifier |
| Asiminacin | Fruit peel | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | No resolvable identifier |
| Epi-magnolin a | Leaves | Solvent extraction | ≥ 0.84 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | No resolvable identifier |
| Epi-magnolin a | Leaves | Solvent extraction | ≤ 2.07 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | No resolvable identifier |
| Lignans | Leaves | Solvent extraction | — | Unspecified | No resolvable identifier |
| Liriodenine | Bark | Solvent extraction | — | Colorimetry, Spectroscopy (Spectrometry) and Photometry | No resolvable identifier |
| Yangambin | Leaves | Solvent extraction | ≥ 0.58 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | No resolvable identifier |
| Yangambin | Leaves | Solvent extraction | ≤ 1.38 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- SHI, GE., ZENG, L., GU, ZM., MACDOUGAL, JM., MCLAUGHLIN, JL. ABSOLUTE STEREOCHEMISTRIES OF SYLVATICIN AND 12,15-CIS-SYLVATICIN, BIOACTIVE C-20,23-CIS NON-ADJACENT BISTETRAHYDROFURAN ANNONACEOUS ACETOGENINS, FROM ROLLINIA-MUCOSA . Heterocycles, 1995, vol. 41, no. 8, p. 1785-1796.
- Figueiredo, SFL., Viana, VRC., Simoes, C., Albarello, N., Trugo, LC., Kaplan, MAC., Krul, WR. Lignans from leaves, seedlings and micropropagated plants of Rollinia mucosa (Jacq.) Baill. - Annonaceae. PLANT CELL TISSUE AND ORGAN CULTURE, 1999, vol. 56, no. 2, p. 121-124.
- Yoshimitsu, T., Makino, T., Nagaoka, H. Total synthesis of (+)-muconin. Journal of organic chemistry, 2004, vol. 69, no. 6, p. 1993-1998. DOI
- Gu, ZM., Zhou, DW., Wu, J., Shi, G., Zeng, L., McLaughlin, JL. Screening for Annonaceous acetogenins in bioactive plant extracts by liquid chromatography mass spectrometry . Journal of natural products, 1997, vol. 60, no. 3, p. 242-248. DOI
- Chavez, D., Acevedo, LA., Mata, R. Tryptamine derived amides and acetogenins from the seeds of Rollinia mucosa. JOURNAL OF NATURAL PRODUCTS, 1999, vol. 62, no. 8, p. 1119-1122. DOI
- Shi, G., Ye, Q., He, K., McLaughlin, JL., MacDougal, JM. Rollinecins A and B: Two new bioactive annonaceous acetogenins from Rollinia mucosa. JOURNAL OF NATURAL PRODUCTS, 1996, vol. 59, no. 5, p. 548-551. DOI
- Wishart, DS., Jewison, T., Guo, AC., Wilson, M., Knox, C., Liu, Y., Djoumbou, Y., Mandal, R., Aziat, F., Dong, E., Bouatra, S., Sinelnikov, I., Arndt, D., Xia, J., Liu, P., Yallou, F., Bjorndahl, T., Perez-Pineiro, R., Eisner, R., Allen, F., Neveu, V., Greiner, R., Scalbert, A. N-Methoxycarbonylanonaine (HMDB41538).. Human metabolome database, 2012, vol. 3.0.
- Chen, YY., Chang, FR., Yen, HF., Wu, YC. Epomusenins A and B, two acetogenins from fruits of Rollinia mucosa. PHYTOCHEMISTRY, 1996, vol. 42, no. 4, p. 1081-1083. DOI
- Chavez, D., Acevedo, LA., Mata, R. Jimenezin, a novel annonaceous acetogenin from the seeds of Rollinia mucosa containing adjacent tetrahydrofuran-tetrahydropyran ring systems . Journal of natural products, 1998, vol. 61, no. 4, p. 419-421. DOI
- Gu, ZM., Zhou, DW., Lewis, NJ., Wu, J., Shi, GE., McLaughlin, JL. Isolation of new bioactive annonaceous acetogenins from Rollinia mucosa guided by liquid chromatography mass spectrometry. BIOORGANIC & MEDICINAL CHEMISTRY, 1997, vol. 5, no. 10, p. 1911-1916. DOI
- Caetano, Luis Carlos., Dadoun, Henri. Alkaloids of the Annonaceae. Part 73. Pallidine and aporphinoid alkaloids from Rollinia mucosa. Journal of Natural Products, 1987.
- Tibirica, E. Cardiovascular properties of yangambin, a lignan isolated from Brazilian plants. CARDIOVASCULAR DRUG REVIEWS, 2001, vol. 19, no. 4, p. 313-328.
- Luo, Rensheng., Maia, Jose Guilherme S., Rosa de Moraes, Maria., Godoy, Helena T., Sabaa-Srur, Armando A. U., Tran, Kevin., Richards, Kristy M., Monroe, Douglas M., Vocque, Ralph H., Smith, Robert E. NMR analysis of potentially neurotoxic annonaceous fruits. Natural products journal, 2013, p. 230-241.
- Wishart, DS., Jewison, T., Guo, AC., Wilson, M., Knox, C., Liu, Y., Djoumbou, Y., Mandal, R., Aziat, F., Dong, E., Bouatra, S., Sinelnikov, I., Arndt, D., Xia, J., Liu, P., Yallou, F., Bjorndahl, T., Perez-Pineiro, R., Eisner, R., Allen, F., Neveu, V., Greiner, R., Scalbert, A. N-Methoxycarbonyl-N-nornuciferine (HMDB36988).. Human metabolome database, 2012, vol. 3.0.
- Chen, YY., Chang, FR., Wu, YC. Isoquinoline alkaloids and lignans from Rollinia mucosa. JOURNAL OF NATURAL PRODUCTS, 1996, vol. 59, no. 9, p. 904-906. DOI
- Kuo, RY., Chang, FR., Chen, CY., Teng, CM., Yen, HF., Wu, YC. Antiplatelet activity of N-methoxycarbonyl aporphines from Rollinia mucosa. PHYTOCHEMISTRY, 2001, vol. 57, no. 3, p. 421-425. DOI
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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