Botanical species · safety record

Rosa rugosa

The EFSA Compendium of Botanicals holds 12 constituent measurements and 4 adverse-effect records for Rosa rugosa. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Rosa rugosa Thunb.

12Constituent measurements
4Safety records
11Cited sources
20Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 20 licensed products naming Rosa rugosa as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

  • Dry

Source material stated

  • Flower
  • Flower buds

What the records describe

Constituents measured

  • Benzene-1,2-diol1
  • Digalloylglucose1
  • Ellagitannins (hydrolysable tannins)1
  • Gallic acid1
  • Gallotannins1
  • Hydroxymethylfurfural1
  • Isoflavones1
  • Methyleugenol1
  • Pratensein1
  • Proanthocyanidins (condensed tannins)1

Plant parts

  • Flower9
  • Bud3
  • Fruit unspecified3
  • Roots and other underground parts1

Preparations

  • Solvent extraction10
  • Essential oil1

Effect types

  • Digestive4

Target tissues

  • Digestive2
  • Digestive: pancreas2

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
DigalloylglucoseFlowerSolvent extractionUV/VIS spectroscopy (photometry)Resolve DOI
Gallic acidFruit unspecifiedSolvent extraction92.4 Milligram/100 gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
GallotanninsFlowerSolvent extractionHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
IsoflavonesBudHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
PratenseinBudHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
PrunetinBudHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
Triterpene saponinsRoots and other underground partsLC-MSResolve DOI
Benzene-1,2-diolFruit unspecifiedSolvent extractionStandard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier
Ellagitannins (hydrolysable tannins)FlowerUnspecifiedNo resolvable identifier
HydroxymethylfurfuralFlowerSolvent extraction3.6 Milligram/100 gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)No resolvable identifier
MethyleugenolFlowerEssential oil6.88 PercentUnspecifiedNo resolvable identifier
Proanthocyanidins (condensed tannins)Fruit unspecifiedSolvent extraction25620.26 Microgram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

EffectTarget tissuePlant partPreparationTest organismTest typeSource
DigestiveDigestive: pancreasFlowerSolvent extractionIn vitroResolve DOI
DigestiveDigestive: pancreasFlowerSolvent extractionIn vitroResolve DOI
DigestiveDigestiveFlowerSolvent extractionIn vitroResolve DOI
DigestiveDigestiveFlowerSolvent extractionIn vitroResolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Li, L.-M., Lou, J., Liu, G.-Y., Wang, H., Yang, J.-X., Wang, Y.-D., Dong, W., Zhou, K., Hu, Q.-F. Isoflavones from flower buds of Rosa rugosa and their cytotoxicity. Chinese traditional and herbal drugs, 2015, vol. 46, no. 10, p. 1420-1422. DOI
  2. Teleszko, Miroslawa., Wojdylo, Aneta., Oszmianski, Jan. CONTENT OF ELLAGIC ACID AND POLYMERIZED PROANTHOCYANIDINS IN PSEUDO FRUITS OF SELECTED ROSE SPECIES . Zywnosc-nauka technologia jakosc, 2012, vol. 19, no. 5, p. 37-46.
  3. Wu, Chengshun., Wang, Yi., Zhao, Dexiu., Sun, Shouwei., Ma, Yaping., Chen, Jian. The main chemical components of the essential oil from Rosa rugosa Thunb. Zhiwu xuebao, 1985, vol. 27, no. 5, p. 510-15.
  4. Cendrowski, Andrzej., Scibisz, Iwona., Mitek, Marta. THE CONTENT OF HYDROXYMETHYLFURFURAL IN CONFITURES FROM PETALS OF ROSA RUGOSA . Bromatologia i chemia toksykologiczna, 2016, vol. 49, no. 3, p. 238-242.
  5. Gu, Dongyu., Yang, Yi., Bakri, Mahinur., Chen, Qibin., Xin, Xuelei., Aisa, Haji Akber. A LC/QTOF-MS/MS Application to Investigate Chemical Compositions in a Fraction with Protein Tyrosine Phosphatase 1B Inhibitory Activity from Rosa Rugosa Flowers . Phytochemical analysis, 2013, vol. 24, no. 6, p. 661-670. DOI
  6. Hallmann, E., Orpel, E., Rembialkowska, E. The content of biologically active compounds in some fruits from natural state Zawartosc zwiazk�w biologicznie czynnych w r�znych owocach ze stanu naturalnego . Vegetable crops research bulletin, 2011, vol. 75, no. 1, p. 81-90. DOI
  7. Li, D. Q., Zhao, J., Xie, J., Li, S. P. A novel sample preparation and on-line HPLC-DAD-MS/MS-BCD analysis for rapid screening and characterization of specific enzyme inhibitors in herbal extracts: Case study of alpha-glucosidase . Journal of pharmaceutical and biomedical analysis, 2014, vol. 88, p. 130-135. DOI
  8. An, Hyo-Jin., Kim, In-Tae., Park, Hee-Juhn., Kim, Hyung-Min., Choi, Jung-Hye., Lee, Kyung-Tae. Tormentic acid, a triterpenoid saponin, isolated from Rosa rugosa, inhibited LPS-induced iNOS, COX-2, and TNF-alpha expression through inactivation of the nuclear factor-kappa b pathway in RAW 264.7 macrophages . International immunopharmacology, 2011, vol. 11, no. 4, p. 504-510. DOI
  9. Shnaidman, L. O., Kushchinskaya, I. N. Identification of the flavone and catechol compounds in the fruits of Rosa cinnamomea and Rosa rugosa. Meditsinskaya promyshlennost sssr, 1965, vol. 19, no. 2, p. 14-17.
  10. Feng, Shengbao., Song, Lixia., Liu, Yuancai., Lai, Fuli., Zuo, Gang., He, Guangyuan., Chen, Mingjie., Huang, Dejian. Hypoglycemic Activities of Commonly-Used Traditional Chinese Herbs. American journal of chinese medicine, 2013, vol. 41, no. 4, p. 849-864. DOI
  11. Borkowski, B., Milkowska, K. Tannins, tannoids and related compounds. III. Ellagitannin. Herba polonica, 1996, vol. 42, no. 2, p. 118-126.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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