Botanical species · safety record
Rosa rugosa
The EFSA Compendium of Botanicals holds 12 constituent measurements and 4 adverse-effect records for Rosa rugosa. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Rosa rugosa Thunb.
Regulatory presence
Health Canada's Licensed Natural Health Products Database holds 20 licensed products naming Rosa rugosa as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.
Extract types on licence
Source material stated
What the records describe
Constituents measured
- Benzene-1,2-diol1
- Digalloylglucose1
- Ellagitannins (hydrolysable tannins)1
- Gallic acid1
- Gallotannins1
- Hydroxymethylfurfural1
- Isoflavones1
- Methyleugenol1
- Pratensein1
- Proanthocyanidins (condensed tannins)1
Plant parts
- Flower9
- Bud3
- Fruit unspecified3
- Roots and other underground parts1
Preparations
- Solvent extraction10
- Essential oil1
Effect types
- Digestive4
Target tissues
- Digestive2
- Digestive: pancreas2
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Digalloylglucose | Flower | Solvent extraction | — | UV/VIS spectroscopy (photometry) | Resolve DOI |
| Gallic acid | Fruit unspecified | Solvent extraction | 92.4 Milligram/100 gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Gallotannins | Flower | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Isoflavones | Bud | — | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Pratensein | Bud | — | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Prunetin | Bud | — | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Triterpene saponins | Roots and other underground parts | — | — | LC-MS | Resolve DOI |
| Benzene-1,2-diol | Fruit unspecified | Solvent extraction | — | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
| Ellagitannins (hydrolysable tannins) | Flower | — | — | Unspecified | No resolvable identifier |
| Hydroxymethylfurfural | Flower | Solvent extraction | 3.6 Milligram/100 gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | No resolvable identifier |
| Methyleugenol | Flower | Essential oil | 6.88 Percent | Unspecified | No resolvable identifier |
| Proanthocyanidins (condensed tannins) | Fruit unspecified | Solvent extraction | 25620.26 Microgram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | No resolvable identifier |
Recorded adverse effects
Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.
| Effect | Target tissue | Plant part | Preparation | Test organism | Test type | Source |
|---|---|---|---|---|---|---|
| Digestive | Digestive: pancreas | Flower | Solvent extraction | — | In vitro | Resolve DOI |
| Digestive | Digestive: pancreas | Flower | Solvent extraction | — | In vitro | Resolve DOI |
| Digestive | Digestive | Flower | Solvent extraction | — | In vitro | Resolve DOI |
| Digestive | Digestive | Flower | Solvent extraction | — | In vitro | Resolve DOI |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Li, L.-M., Lou, J., Liu, G.-Y., Wang, H., Yang, J.-X., Wang, Y.-D., Dong, W., Zhou, K., Hu, Q.-F. Isoflavones from flower buds of Rosa rugosa and their cytotoxicity. Chinese traditional and herbal drugs, 2015, vol. 46, no. 10, p. 1420-1422. DOI
- Teleszko, Miroslawa., Wojdylo, Aneta., Oszmianski, Jan. CONTENT OF ELLAGIC ACID AND POLYMERIZED PROANTHOCYANIDINS IN PSEUDO FRUITS OF SELECTED ROSE SPECIES . Zywnosc-nauka technologia jakosc, 2012, vol. 19, no. 5, p. 37-46.
- Wu, Chengshun., Wang, Yi., Zhao, Dexiu., Sun, Shouwei., Ma, Yaping., Chen, Jian. The main chemical components of the essential oil from Rosa rugosa Thunb. Zhiwu xuebao, 1985, vol. 27, no. 5, p. 510-15.
- Cendrowski, Andrzej., Scibisz, Iwona., Mitek, Marta. THE CONTENT OF HYDROXYMETHYLFURFURAL IN CONFITURES FROM PETALS OF ROSA RUGOSA . Bromatologia i chemia toksykologiczna, 2016, vol. 49, no. 3, p. 238-242.
- Gu, Dongyu., Yang, Yi., Bakri, Mahinur., Chen, Qibin., Xin, Xuelei., Aisa, Haji Akber. A LC/QTOF-MS/MS Application to Investigate Chemical Compositions in a Fraction with Protein Tyrosine Phosphatase 1B Inhibitory Activity from Rosa Rugosa Flowers . Phytochemical analysis, 2013, vol. 24, no. 6, p. 661-670. DOI
- Hallmann, E., Orpel, E., Rembialkowska, E. The content of biologically active compounds in some fruits from natural state Zawartosc zwiazk�w biologicznie czynnych w r�znych owocach ze stanu naturalnego . Vegetable crops research bulletin, 2011, vol. 75, no. 1, p. 81-90. DOI
- Li, D. Q., Zhao, J., Xie, J., Li, S. P. A novel sample preparation and on-line HPLC-DAD-MS/MS-BCD analysis for rapid screening and characterization of specific enzyme inhibitors in herbal extracts: Case study of alpha-glucosidase . Journal of pharmaceutical and biomedical analysis, 2014, vol. 88, p. 130-135. DOI
- An, Hyo-Jin., Kim, In-Tae., Park, Hee-Juhn., Kim, Hyung-Min., Choi, Jung-Hye., Lee, Kyung-Tae. Tormentic acid, a triterpenoid saponin, isolated from Rosa rugosa, inhibited LPS-induced iNOS, COX-2, and TNF-alpha expression through inactivation of the nuclear factor-kappa b pathway in RAW 264.7 macrophages . International immunopharmacology, 2011, vol. 11, no. 4, p. 504-510. DOI
- Shnaidman, L. O., Kushchinskaya, I. N. Identification of the flavone and catechol compounds in the fruits of Rosa cinnamomea and Rosa rugosa. Meditsinskaya promyshlennost sssr, 1965, vol. 19, no. 2, p. 14-17.
- Feng, Shengbao., Song, Lixia., Liu, Yuancai., Lai, Fuli., Zuo, Gang., He, Guangyuan., Chen, Mingjie., Huang, Dejian. Hypoglycemic Activities of Commonly-Used Traditional Chinese Herbs. American journal of chinese medicine, 2013, vol. 41, no. 4, p. 849-864. DOI
- Borkowski, B., Milkowska, K. Tannins, tannoids and related compounds. III. Ellagitannin. Herba polonica, 1996, vol. 42, no. 2, p. 118-126.
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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