Botanical species · safety record

Rubus idaeus

The EFSA Compendium of Botanicals holds 25 constituent measurements for Rubus idaeus. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Rubus idaeus L.

25Constituent measurements
0Safety records
7Cited sources
588Licensed products (Canada)

Also recorded as

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 588 licensed products naming Rubus idaeus as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

  • Dry
  • Extract Type TBA
  • Fresh

Source material stated

  • Berries
  • Berry (standardized extract)
  • Berry/Berries
  • Dried leaf
  • Edible fruit part
  • Fruit
  • Fruit concentrate
  • Fruit extract

What the records describe

Constituents measured

  • Ellagitannins (hydrolysable tannins)3
  • Alkaloids2
  • Lignans2
  • Oxalic acid2
  • Proanthocyanidins (condensed tannins)2
  • 3,4-dihydroxybenzoic acid1
  • Epigallocatechin1
  • Epigallocatechin gallate1
  • Gallic acid1
  • Gallocatechin1

Plant parts

  • Fruit unspecified12
  • Unspecified7
  • Leaves6

Preparations

  • Solvent extraction22

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
3,4-dihydroxybenzoic acidLeavesSolvent extraction—UHPLC-MS-MSResolve DOI
Ellagitannins (hydrolysable tannins)Fruit unspecifiedSolvent extraction260 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
Ellagitannins (hydrolysable tannins)Fruit unspecifiedSolvent extraction≥ 53.5 PercentHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
Ellagitannins (hydrolysable tannins)Fruit unspecifiedSolvent extraction≤ 75.9 PercentHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
EpigallocatechinLeavesSolvent extraction—UHPLC-MS-MSResolve DOI
Epigallocatechin gallateLeavesSolvent extraction—UHPLC-MS-MSResolve DOI
Gallic acidLeavesSolvent extraction—UHPLC-MS-MSResolve DOI
GallocatechinLeavesSolvent extraction—UHPLC-MS-MSResolve DOI
P-coumaric acidLeavesSolvent extraction—UHPLC-MS-MSResolve DOI
Proanthocyanidins (condensed tannins)Fruit unspecifiedSolvent extraction—High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
Proanthocyanidins (condensed tannins)Fruit unspecifiedSolvent extraction16.9 PercentHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
AlkaloidsUnspecifiedSolvent extraction—Mass Spectroscopy and hyphenated methods without chromatographyNo resolvable identifier
AlkaloidsUnspecifiedSolvent extraction—Mass Spectroscopy and hyphenated methods without chromatographyNo resolvable identifier
GenisteinFruit unspecifiedSolvent extraction—GC-MSNo resolvable identifier
Indole alkaloidsUnspecifiedSolvent extraction—Mass Spectroscopy and hyphenated methods without chromatographyNo resolvable identifier
Isoquinoline alkaloidsUnspecifiedSolvent extraction—Mass Spectroscopy and hyphenated methods without chromatographyNo resolvable identifier
LariciresinolFruit unspecified—13 Microgram/100 gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)No resolvable identifier
LignansFruit unspecifiedSolvent extraction1390 Microgram/kilogramGC-MSNo resolvable identifier
LignansFruit unspecified—11 Microgram/100 gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)No resolvable identifier
Oxalic acidFruit unspecifiedSolvent extraction≥ 5.25 Milligram/gram—No resolvable identifier
Oxalic acidFruit unspecifiedSolvent extraction≤ 9.54 Milligram/gram—No resolvable identifier
PinoresinolFruit unspecified—142 Microgram/100 gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)No resolvable identifier
Quinoline alkaloidsUnspecifiedSolvent extraction—Mass Spectroscopy and hyphenated methods without chromatographyNo resolvable identifier
Quinolizidine alkaloidsUnspecifiedSolvent extraction—Mass Spectroscopy and hyphenated methods without chromatographyNo resolvable identifier
Tropane alkaloidsUnspecifiedSolvent extraction—Mass Spectroscopy and hyphenated methods without chromatographyNo resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Sembratowicz, Iwona., Ognik, Katarzyna., Rusinek, Elzbieta., Truchlinski, Jerzy. Contents of tannins and oxalic acid in the selected forest fruits depending on the harvest site . . Roczniki panstwowego zakladu higieny, 2008, vol. 59, no. 1, p. 41-6.
  2. Mazur, W. M., Uehara, M., Wahala, K., Adlercreutz, H. Phyto-oestrogen content of berries, and plasma concentrations and urinary excretion of enterolactone after a single strawberry-meal in human subjects. British journal of nutrition, 2000, vol. 83, no. 4, p. 381-387.
  3. Kreander, Kari., Galkin, Anna., Vuorela, Satu., Tammela, Paivi., Laitinen, Leena., Heinonen, Marina., Vuorela, Pia. In-vitro mutagenic potential and effect on permeability of co-administered drugs across Caco-2 cell monolayers of Rubus idaeus and its fortified fractions . Journal of pharmacy and pharmacology, 2006, vol. 58, no. 11, p. 1545-1552. DOI
  4. Nurmi, Tarja., Mursu, Jaakko., Penalvo, Jose L., Poulsen, Henrik E., Voutilainen, Sari. Dietary intake and urinary excretion of lignans in Finnish men. British journal of nutrition, 2010, vol. 103, no. 5, p. 677-685.
  5. Sojka, Michal., Macierzynski, Jakub., Zaweracz, Wojciech., Buczek, Maria. Transfer and Mass Balance of Ellagitannins, Anthocyanins, Flavan-3-ols, and Flavonols during the Processing of Red Raspberries (Rubus idaeus L.) to Juice . Journal of agricultural and food chemistry, 2016, vol. 64, no. 27, p. 5549-5563. DOI
  6. Nardin, Tiziana., Piasentier, Edi., Barnaba, Chiara., Larcher, Roberto. Alkaloid profiling of herbal drugs using high resolution mass spectrometry. Drug testing and analysis, 2017, p. Ahead of Print.
  7. Pavlovic, Aleksandra V., Papetti, Adele., Dabic Zagorac, Dragana., Gasic, Uros M., Misic, Danijela M., Tesic, Zivoslav Lj., Natic, Maja M. Phenolics composition of leaf extracts of raspberry and blackberry cultivars grown in Serbia . Industrial crops and products, 2016, vol. 87, p. 304-314. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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