Botanical species · safety record

Ruscus aculeatus

The EFSA Compendium of Botanicals holds 8 constituent measurements for Ruscus aculeatus. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Ruscus aculeatus L.

8Constituent measurements

0Safety records

5Cited sources

73Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 73 licensed products naming Ruscus aculeatus as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Dry
Extract Type TBA
Fresh

Source material stated

Carefully dried or fresh underground parts
Fresh underground part(s)
Fresh underground parts
Rhiencephalon
Rhizome
Rhizome and root(s)
Root
Root and rhizome

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Coumarins	Roots and other underground parts	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Ruscogenin	Roots and other underground parts	Solvent extraction	0.9 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Ruscogenin	Aerial part of plants	Solvent extraction	0.7 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Saponins	Roots and other underground parts	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Saponins	Roots and other underground parts	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Steroidal saponins	Roots and other underground parts	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Neoruscogenin	Live plants	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	No resolvable identifier
Ruscogenin	Live plants	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Guevenc, A., Satir, E., Coskun, M. Determination of ruscogenin in Turkish Ruscus l. species by UPLC. Chromatographia, 2007, vol. 66, p. S141-S145. DOI
Robert, Jean., Vaupre, Roger., Poiget, Gilbert. The constitution of neoruscogenin. Compt. rend., 1960, vol. 250, p. 3187-9.
Barbic, M., Willer, E. A., Rothenhoefer, M., Heilmann, J., Fuerst, R., Juergenliemk, G. Spirostanol saponins and esculin from Rusci rhizoma reduce the thrombin-induced hyperpermeability of endothelial cells . Phytochemistry, 2013, vol. 90, p. 106-113. DOI
Burn, D., Ellis, B., Petrow, V. Structure of ruscogenin. Journal of the chemical society, 1958, p. 795-9.
Walthelm, U., Dittrich, K., Gelbrich, G., Schopke, T. Effects of saponins on the water solubility of different model compounds. Planta medica, 2001, vol. 67, no. 1, p. 49-54. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature