Botanical species · safety record

Salvadora persica

The EFSA Compendium of Botanicals holds 13 constituent measurements and 2 adverse-effect records for Salvadora persica. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Salvadora persica L.

13Constituent measurements

2Safety records

9Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Eleutheroside b	Stem / stalk	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Eugenol	Leaves	Essential oil	10.49 Percent	GC-MS	Resolve DOI
Liriodendrin	Stem / stalk	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Tannins	Fruit unspecified	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
(-)-globulol	Leaves	Solvent extraction	—	GC-MS	No resolvable identifier
Alkaloids	Leaves	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Alkaloids	Live plants	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Cardiac glycosides	Live plants	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Coumarins	Leaves	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Glucotropaeolin	Roots and other underground parts	—	—	Unspecified	No resolvable identifier
Malvalic acid	Seed	—	7.8 Percent	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Quinones	Leaves	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Sterculic acid	Seed	—	3.5 Percent	Nuclear Magnetic Resonance (NMR)	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Reproductive	Urogenital: ovaries	Wood	Solvent extraction	House mouse (as animal)	Reproduction toxicity	No resolvable identifier
Reproductive	Testes	Wood	Solvent extraction	House mouse (as animal)	Reproduction toxicity	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Bansode, T.S., Salalkar, B.K. Phytochemical analysis of some selected Indian medicinal plants. International journal of pharma and bio sciences, 2015, vol. 6, no. 1, p. P550-P556.
Darmani H., Al-Hiyasat A S., Elbetieha A M., Alkofahi A. The effect of an extract of Salvadora persica (Meswak, chewing stick) on fertility of male and female mice. Phytomedicine : international journal of phytotherapy and phytopharmacology, 2003, vol. 10, no. 1, p. 63-5.
Reema, B., Detroja, D., Pandya, R.V., Tank, J.G. Salvadora persica: A potential source for treatment of hypercholesterolemia. Plant archives, 2017, vol. 17, no. 2, p. 955-960.
Mariita, R.M., Ogol, C.K.P.O., Oguge, N.O., Okemo, P.O. Antitubercular and phytochemical investigation of methanol extracts of medicinal plants used by the samburu community in Kenya. Tropical journal of pharmaceutical research, 2010, vol. 9, no. 4, p. 379-385.
KAMEL, MS., OHTANI, K., ASSAF, MH., KASAI, R., ELSHANAWANI, MA., YAMASAKI, K., ALI, AA., TANAKA, O. LIGNAN GLYCOSIDES FROM STEMS OF SALVADORA-PERSICA. Phytochemistry, 1992, vol. 31, no. 7, p. 2469-2471. DOI
Ezmirly, Saleh T., Seif El-Nasr, Medhat M. Isolation of glucotropaeolin from Salvadora persica L. Journal of the chemical society of pakistan, 1981, vol. 3, no. 1, p. 9-12.
Hosamani, K. M., Pattanashettar, R. S. Salvadora persica seed oil: A rich source of oil and minor source of cyclopropenoid fatty acids. . Journal of medicinal and aromatic plant sciences, 2002, vol. 24, no. 3, p. 713-715.
Gupta, Mradu., Shaw, B P., Mukherjee, A. A new glycosidic flavonoid from Jwarhar mahakashay (antipyretic) Ayurvedic preparation. . International journal of ayurveda research, 2010, vol. 1, no. 2, p. 106-11. DOI
Alali, F., Al-Lafi, T. GC-MS analysis and bioactivity testing of the volatile oil from the leaves of the toothbrush tree Salvadora persica L. . Natural product research, 2003, vol. 17, no. 3, p. 189-194. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature