Botanical species · safety record

Salvia divinorum

The EFSA Compendium of Botanicals holds 4 constituent measurements and 1 adverse-effect record for Salvia divinorum. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Salvia divinorum Epling & Játiva

4Constituent measurements

1Safety records

3Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Salvinorin a	Leaves	Solvent extraction	≤ 0.3 Percent	HPLC with standard detection methods	Resolve DOI
Salvinorin a	Leaves	Solvent extraction	≥ 81.04 Microgram/100 millilitre	HPLC-UV	Resolve DOI
Salvinorin a	Leaves	Solvent extraction	≤ 87.16 Microgram/100 millilitre	HPLC-UV	Resolve DOI
Salvinorin a	Leaves	Solvent extraction	≥ 0.25 Percent	HPLC with standard detection methods	Resolve DOI

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Neurotoxicity	Neurologic	—	—	Human (as organism)	Case report	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Shirota, Osamu., Nagamatsu, Kumi., Sekita, Setsuko. Simple preparative isolation of salvinorin a from the hallucinogenic sage, Salvia divinorum, by centrifugal partition chromatography . Journal of liquid chromatography & related technologies, 2007, vol. 30, no. 5-8, p. 1105-1114. DOI
Vohra, Rais., Seefeld, Andrew., Cantrell, F. Lee., Clark, Richard F. SALVIA DIVINORUM: EXPOSURES REPORTED TO A STATEWIDE POISON CONTROL SYSTEM OVER 10 YEARS . Journal of emergency medicine, 2011, vol. 40, no. 6, p. 643-650. DOI
Lin, Po-Xiang., Li, Jih-Heng., Chen, Su-Hwei., Chang, Hsien-Chang., McKetin, Rebecca. Quantitative determination of salvinorin A, a natural hallucinogen with abuse liability, in Internet-available Salvia divinorum and endemic species of Salvia in Taiwan . Journal of food and drug analysis, 2014, vol. 22, no. 3, p. 370-378. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature