Botanical species · safety record

Salvia officinalis

The EFSA Compendium of Botanicals holds 42 constituent measurements for Salvia officinalis. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Salvia officinalis L.

42Constituent measurements

0Safety records

9Cited sources

445Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 445 licensed products naming Salvia officinalis as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Dry
Fresh

Source material stated

Aerial parts
Allium sativum - Bulb
Dried leaf
Flowering tops
Fresh leaves
Fresh leaves and flowering tops
Herb
Herb top

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
1,8-cineole	Leaves	Essential oil	≤ 45.3 Percent	GC-FID	Resolve DOI
1,8-cineole	Leaves	Essential oil	≥ 2.7 Percent	GC-FID	Resolve DOI
1,8-cineole	Aerial part of plants	Solvent extraction	14.43 Percent	GC-FID-MS	Resolve DOI
1,8-cineole	Unspecified	Essential oil	47 Percent	Unspecified	Resolve DOI
1,8-cineole	Aerial part of plants	Essential oil	≤ 62.7 Percent	GC-MS	Resolve DOI
1,8-cineole	Unspecified	Essential oil	3.5 Percent	Unspecified	Resolve DOI
1,8-cineole	Aerial part of plants	Essential oil	25.5 Percent	GC-MS	Resolve DOI
1,8-cineole	Aerial part of plants	Essential oil	≥ 17.9 Percent	GC-MS	Resolve DOI
1,8-cineole	Aerial part of plants	Essential oil	≥ 5.7 Percent	GC-MS	Resolve DOI
1,8-cineole	Aerial part of plants	Essential oil	≤ 54.7 Percent	GC-MS	Resolve DOI
Alpha-thujone	Aerial part of plants	Solvent extraction	37.52 Percent	GC-FID-MS	Resolve DOI
Alpha-thujone	Leaves	Essential oil	≥ 3 Percent	GC-FID	Resolve DOI
Alpha-thujone	Leaves	Essential oil	≤ 26.6 Percent	GC-FID	Resolve DOI
Alpha-thujone	Unspecified	Essential oil	36 Percent	Unspecified	Resolve DOI
Beta-thujone	Leaves	Essential oil	1.13 Percent	GC-MS	Resolve DOI
Beta-thujone	Aerial part of plants	Solvent extraction	4.67 Percent	GC-FID-MS	Resolve DOI
Beta-thujone	Leaves	Essential oil	≥ 1.5 Percent	GC-FID	Resolve DOI
Beta-thujone	Leaves	Essential oil	≤ 12.9 Percent	GC-FID	Resolve DOI
Beta-thujone	Unspecified	Essential oil	9.7 Percent	Unspecified	Resolve DOI
Camphor	Leaves	Essential oil	≤ 29.8 Percent	GC-FID	Resolve DOI
Camphor	Aerial part of plants	Solvent extraction	13.77 Percent	GC-FID-MS	Resolve DOI
Camphor	Leaves	Essential oil	≥ 11.3 Percent	GC-FID	Resolve DOI
Camphor	Unspecified	Essential oil	9.6 Percent	Unspecified	Resolve DOI
Camphor	Aerial part of plants	Essential oil	≤ 28.7 Percent	GC-MS	Resolve DOI
Camphor	Unspecified	Essential oil	12.6 Percent	Unspecified	Resolve DOI
Camphor	Aerial part of plants	Essential oil	≥ 0.6 Percent	GC-MS	Resolve DOI
Camphor	Aerial part of plants	Essential oil	39 Percent	GC-MS	Resolve DOI
Camphor	Aerial part of plants	Essential oil	≥ 1.5 Percent	GC-MS	Resolve DOI
Camphor	Aerial part of plants	Essential oil	≤ 20.4 Percent	GC-MS	Resolve DOI
Myrcene	Leaves	Essential oil	≤ 4.2 Percent	GC-FID	Resolve DOI
Myrcene	Leaves	Essential oil	≥ 0.1 Percent	GC-FID	Resolve DOI
Myrcene	Leaves	Essential oil	3.01 Percent	GC-MS	Resolve DOI
Myrcene	Unspecified	Essential oil	5.8 Percent	Unspecified	Resolve DOI
1,8-cineole	Leaves	Essential oil	22.83 Percent	GC-MS	No resolvable identifier
1,8-cineole	Flowering top	Essential oil	8.13 Percent	GC-MS	No resolvable identifier
Alpha-thujone	Leaves	Essential oil	4.29 Percent	GC-MS	No resolvable identifier
Alpha-thujone	Flowering top	Essential oil	18.95 Percent	GC-MS	No resolvable identifier
Beta-thujone	Leaves	Essential oil	25.05 Percent	GC-MS	No resolvable identifier
Beta-thujone	Flowering top	Essential oil	19.96 Percent	GC-MS	No resolvable identifier
Camphor	Leaves	Essential oil	18.38 Percent	GC-MS	No resolvable identifier

40 of 42 records are shown, ordered so that records carrying a resolvable reference come first.

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Diab, Kawthar Ae., Fahmy, Maha A., Hassan, Zeinab M., Hassan, Emad M., Salama, Adel B., Omara, Enayat A. Genotoxicity of carbon tetrachloride and the protective role of essential oil of Salvia officinalis L. in mice using chromosomal aberration, micronuclei formation, and comet assay. . Environmental science and pollution research international, 2017. DOI
Demirel, N., Sener, O., Arslan, M., Uremis, I., Uluc, F. T., Cabuk, F. Toxicological Responses of Confused Flour Beetle, Tribolium confusum du Val (Coleoptera: Tenebrinoidea) to Various Plant Essential Oils . Asian journal of chemistry, 2009, vol. 21, no. 8, p. 6403-6410.
Raal, Ain., Orav, Anne., Arak, Elmar. Composition of the essential oil of Salvia officinalis L. from various European countries . Natural product research, 2007, vol. 21, no. 5, p. 406-411. DOI
Vukovic-Gacic, B., Nikcevic, S., Beric-Bjedov, T., Knezevic-Vukcevic, J., Simic, D. Antimutagenic effect of essential oil of sage (Salvia officinalis L.) and its monoterpenes against UV-induced mutations in Escherichia coli and Saccharomyces cerevisiae . Food and chemical toxicology, 2006, vol. 44, no. 10, p. 1730-1738. DOI
Mathe, Imre., Mathe, Akos., Hohmann, Judit., Janicsak, Gabor. Volatile and some non-volatile chemical constituents of Mediterranean Salvia species beyond their native area . Israel journal of plant sciences, 2010, vol. 58, no. 3-4, p. 273-277. DOI
Usano-Alemany, Jaime., Pala-Paul, Jesus., Herraiz-Penalver, David. Comprehensive Phenological Description of Essential-Oil Chemotypes of Salvia lavandulifolia VAHL Grown under the Same Environmental Conditions . Chemistry & biodiversity, 2014, vol. 11, no. 12, p. 1963-1977. DOI
Mossi, A. J., Cansian, R. L., Paroul, N., Toniazzo, G., Oliveira, J., V., Pierozan, M. K., Pauletti, G., Rota, L., Santos, A. C. A., Serafini, L. A. Morphological characterisation and agronomical parameters of different species of Salvia sp (Lamiaceae) . Brazilian journal of biology, 2011, vol. 71, no. 1, p. 121-129.
Foray, L., Bertrand, C., Pinguet, F., Soulier, M., Astre, C., Marion, C., P�lissier, Y., Bessi�re, J.M. In vitro cytotoxic activity of three essential oils from salvia species. Journal of essential oil research, 1999, vol. 11, no. 4, p. 522-526. DOI
Usano-Alemany, Jaime., Pala-Paul, Jesus., Herraiz-Penalver, David. Essential oil yields and qualities of different clonal lines of Salvia lavandulifolia monitored in Spain over four years of cultivation . Industrial crops and products, 2016, vol. 80, p. 251-261. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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