Botanical species · safety record

Sambucus ebulus

The EFSA Compendium of Botanicals holds 20 constituent measurements and 1 adverse-effect record for Sambucus ebulus. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Sambucus ebulus L.

20Constituent measurements

1Safety records

8Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Alpha-thujone	Leaves	Essential oil	1.19 Percent	GC-MS	Resolve DOI
Estragole	Leaves	Essential oil	1.39 Percent	GC-MS	Resolve DOI
Eugenol	Leaves	Essential oil	2.05 Percent	GC-MS	Resolve DOI
L-piperitone	Leaves	Essential oil	1.24 Percent	GC-MS	Resolve DOI
Lectins	Aerial part of plants	Solvent extraction	—	MALDI-TOFMS	Resolve DOI
Lectins	Leaves	Solvent extraction	—	Gel electrophoresis	Resolve DOI
Lectins	Aerial part of plants	Solvent extraction	—	MALDI-TOFMS	Resolve DOI
Verbenone	Leaves	Essential oil	1.19 Percent	GC-MS	Resolve DOI
Benzoic acid	Roots and other underground parts	Solvent extraction	—	GC-MS	No resolvable identifier
Eugenol	Fruit unspecified	Essential oil	26.8 Percent	Gaschromatography (GC)	No resolvable identifier
Furfural	Leaves	Solvent extraction	—	GC-MS	No resolvable identifier
Furfural	Roots and other underground parts	Solvent extraction	—	GC-MS	No resolvable identifier
Hydroquinone	Roots and other underground parts	Solvent extraction	—	GC-MS	No resolvable identifier
Hydroquinone	Leaves	Solvent extraction	—	GC-MS	No resolvable identifier
Lectins	Roots and other underground parts	—	—	—	No resolvable identifier
Lectins	Roots and other underground parts	—	—	—	No resolvable identifier
Lectins	Fruit unspecified	—	—	Unspecified	No resolvable identifier
Lectins	Leaves	—	—	Unspecified	No resolvable identifier
Methyl salicylate	Fruit unspecified	Essential oil	≤ 10 Percent	Gaschromatography (GC)	No resolvable identifier
Methyl salicylate	Fruit unspecified	Essential oil	≥ 1 Percent	Gaschromatography (GC)	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Digestive	Stomach	—	—	House mouse (as animal)	Acute toxicity	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Girbes, T., Ferreras, JM., Arias, FJ., Munoz, R., Iglesias, R., Jimenez, P., Rojo, MA., Arias, Y., Perez, Y., Benitez, J., Sanchez, D., Gayoso, MJ. Non-toxic type 2 ribosome-inactivating proteins (RIPs) from Sambucus: Occurrence, cellular and molecular activities and potential uses . Cellular and molecular biology, 2003, vol. 49, no. 4, p. 537-545.
Citores, L., DeBenito, FM., Iglesias, R., Ferreras, JM., Argueso, P., Jimenez, P., Testera, A., Camafeita, E., Mendez, E., Girbes, T. Characterization of a new non-toxic two-chain ribosome-inactivating protein and a structurally-related lectin from rhizomes of dwarf elder (Sambucus ebulus L) . Cellular and molecular biology, 1997, vol. 43, no. 4, p. 485-499.
Jimenez, Pilar., Tejero, Jesus., Cabrero, Patricia., Cordoba-Diaz, Damian., Girbes, Tomas. Differential sensitivity of D-galactose-binding lectins from fruits of dwarf elder (Sambucus ebulus L.) to a simulated gastric fluid . Food chemistry, 2013, vol. 136, no. 2, p. 794-802. DOI
PRIBELA, A., DURCANSKA, J., PIRY, J., KAROVICOVA, J. VOLATILE SUBSTANCES OF DWARS ELDER (SAMBUCUS-EBULUS L) FRUITS. Biologia, 1992, vol. 47, no. 3, p. 225-230.
Feizbakhsh, Alireza., Pazoki, Haniyeh., Mohammadrezaei, Vahid., Ebrahimzadeh, Mohammad Ali. Effect of Phytohormones on the Composition of Sambucus ebulus Leaf Essential Oil . Tropical journal of pharmaceutical research, 2014, vol. 13, no. 4, p. 581-586. DOI
DEBENITO, FM., CITORES, L., IGLESIAS, R., FERRERAS, JM., SORIANO, F., ARIAS, J., MENDEZ, E., GIRBES, T. EBULITINS - A NEW FAMILY OF TYPE-1 RIBOSOME-INACTIVATING PROTEINS (RIBOSOMAL-RNA N-GLYCOSIDASES) FROM LEAVES OF SAMBUCUS-EBULUS L THAT COEXIST WITH THE TYPE-2 RIBOSOME-INACTIVATING PROTEIN EBULIN-1 . Febs letters, 1995, vol. 360, no. 3, p. 299-302. DOI
Popescu, Raul., Chirigiu, Liviu., Bubulica, Maria-Viorica., Averis, Larisa-Marina Elisabeth. Qualitative Screening, of Secondary Metabolites from Sambucus Ebulus Roots by Multiple Analytical Techniques . Revista de chimie, 2014, vol. 65, no. 2, p. 148-151.
Chirigiu, L., Chirigiu, R. G., Tircomnicu, V., Bubulica, M. V. GC-MS ANALYSIS OF CHEMICAL COMPOSITION OF Sambucus ebulus LEAVES. Chemistry of natural compounds, 2011, vol. 47, no. 1, p. 126-127.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

Continue

Independent literature