Botanical species · safety record

Saponaria officinalis

The EFSA Compendium of Botanicals holds 8 constituent measurements and 1 genotoxicity assay for Saponaria officinalis. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Saponaria officinalis L.

8Constituent measurements

1Safety records

5Cited sources

18Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 18 licensed products naming Saponaria officinalis as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Source material stated

Herb
Plante entière
Root

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Benzaldehyde	Flower	—	—	GC-MS	Resolve DOI
Nonanal	Flower	—	—	GC-MS	Resolve DOI
Octanal	Flower	—	—	GC-MS	Resolve DOI
Saponins	Roots and other underground parts	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Saponins	Roots and other underground parts	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Saponins	Roots and other underground parts	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Toluene	Flower	—	—	GC-MS	Resolve DOI
Calcium oxalate	Aerial part of plants	Fresh	—	Microscopic detection	No resolvable identifier

Genotoxicity testing

Outcomes of genotoxicity assays as recorded in the source. A negative assay is a result under those test conditions, not a clearance.

Outcome	Endpoint	Test	Tested organism	Metabolic activation	Source
Ambiguous	DNA damage and/or repair	in vitro mammalian cell micronucleus test	Human (as organism)	No data	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Jurgens, A., Witt, T., Gottsberger, G. Flower scent composition in Dianthus and Saponaria species (Caryophyllaceae) and its relevance for pollination biology and taxonomy . Biochemical systematics and ecology, 2003, vol. 31, no. 4, p. 345-357. DOI
Tutuncu Konyar, Sevil., Ozturk, Necla., Dane, Feruzan. Occurrence, types and distribution of calcium oxalate crystals in leaves and stems of some species of poisonous plants. Botanical studies, 2014, vol. 55, no. 1, p. 1-9.
Thakur, Mayank., Mergel, Katharina., Weng, Alexander., von Mallinckrodt, Benedicta., Gilabert-Oriol, Roger., Duerkop, Horst., Melzig, Matthias F., Fuchs, Hendrik. Targeted tumor therapy by epidermal growth factor appended toxin and purified saponin: An evaluation of toxicity and therapeutic potential in syngeneic tumor bearing mice . Molecular oncology, 2013, vol. 7, no. 3, p. 475-483. DOI
Lu, Yuping., Van, Dang., Deibert, Leah., Bishop, Greg., Balsevich, John. Antiproliferative quillaic acid and gypsogenin saponins from Saponaria officinalis L. roots . Phytochemistry, 2015, vol. 113, p. 108-120. DOI
Poma, A., Zarivi, O., Bianchini, S., Spano, L. The plant ribosome inactivating protein saporin induces micronucleus formation in peripheral human lymphocytes in vitro . Toxicology letters, 1999, vol. 105, no. 1, p. 67-73. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

Continue

Independent literature