Botanical species · safety record

Sarcocephalus latifolius

The EFSA Compendium of Botanicals holds 11 constituent measurements and 2 adverse-effect records for Sarcocephalus latifolius. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Sarcocephalus latifolius (Sm.) E.A.Bruce

11Constituent measurements

2Safety records

6Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Alkaloids	Fruit unspecified	Solvent extraction	—	Phytochemical screening	Resolve DOI
Anthraquinones	Fruit unspecified	Solvent extraction	—	Phytochemical screening	Resolve DOI
Cardiac glycosides	Fruit unspecified	Solvent extraction	—	Phytochemical screening	Resolve DOI
Indole alkaloids	Roots and other underground parts	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Indole alkaloids	Roots and other underground parts	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Saponins	Fruit unspecified	Solvent extraction	—	Phytochemical screening	Resolve DOI
Tannins	Fruit unspecified	Solvent extraction	—	Phytochemical screening	Resolve DOI
Cardiac glycosides	Roots and other underground parts	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Indole alkaloids	Bark	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Saponins	Roots and other underground parts	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Tannins	Roots and other underground parts	Solvent extraction	—	Phytochemical screening	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Hepatotoxicity	Liver	Leaves	Solvent extraction	Rat (as animal)	Short-term toxicity	No resolvable identifier
Nephrotoxicity	Urogenital: kidneys	Leaves	Solvent extraction	Rat (as animal)	Short-term toxicity	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Arome, D., Enegide, C., Ameh, S.F., Agbafor, A., Mbonne, E.R., Monica, I. Absence of anxiolytic activity of Sarcocephalus latifolius fruit extract. Journal of Pharmaceutical Negative Results, 2014, vol. 5, no. 1, p. 4-7. DOI
Yesufu, H.B., Bassi, P.U., Khan, I.Z., Abdulrahaman, F.I., Mohammed, G.T. Phytochemical screening and hepatoprotective properties of the aqueous root bark extract of Sarcocephalus latifolius (Smith) Bruce (African peach). Archives of clinical microbiology, 2010, vol. 1, no. 2 . DOI: 10:3823/207.
Candeias, M. F., Abreu, P., Pereira, A., Cruz-Morais, J. Effects of strictosamide on mouse brain and kidney Na+,K+-ATPase and Mg2+-ATPase activities. JOURNAL OF ETHNOPHARMACOLOGY, 2009, vol. 121, no. 1, p. 117-122. DOI
Abreu, P., Pereira, A. A new indole alkaloid from Sarcocephalus latifolius. HETEROCYCLES, 1998, vol. 48, no. 5, p. 885-891.
Abreu, P., Pereira, A. New indole alkaloids from Sarcocephalus latifolius. Natural product letters, 2001, vol. 15, no. 1, p. 43-48. DOI
Magili, S. T., Maina, H. M., Barminas, J. T., Toma, I. Toxicity study of aqueous leaf extracts of Sarcocephalus latifolius (Rubiaceae) in rats. Merit Research Journal of Environmental Science and Toxicology, 2014, p. 120-128.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature