Botanical species · safety record

Sassafras albidum

The EFSA Compendium of Botanicals holds 20 constituent measurements for Sassafras albidum. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Sassafras albidum (Nutt.) Nees

20Constituent measurements

0Safety records

5Cited sources

0Licensed products (Canada)

Also recorded as

Sassafras officinale Nees & C. H. Eberm.

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
1,8-cineole	Roots and other underground parts	Essential oil	≤ 2.38 Percent	GC-MS	Resolve DOI
1,8-cineole	Roots and other underground parts	Essential oil	≥ 1.14 Percent	GC-MS	Resolve DOI
Bisbenzylisoquinoline alkaloids	Roots and other underground parts	Solvent extraction	—	GC-MS	Resolve DOI
Boldine	Roots and other underground parts	Solvent extraction	—	GC-MS	Resolve DOI
Camphor	Roots and other underground parts	Essential oil	≤ 18.4 Percent	GC-MS	Resolve DOI
Camphor	Roots and other underground parts	Solvent extraction	3.25 Percent	GC-MS	Resolve DOI
Camphor	Roots and other underground parts	Essential oil	≥ 1.18 Percent	GC-MS	Resolve DOI
Carvone	Roots and other underground parts	Essential oil	2.42 Percent	GC-MS	Resolve DOI
Isoboldine	Roots and other underground parts	Solvent extraction	—	GC-MS	Resolve DOI
Methyleugenol	Roots and other underground parts	Solvent extraction	1.1 Percent	GC-MS	Resolve DOI
Reticuline	Roots and other underground parts	Solvent extraction	—	GC-MS	Resolve DOI
Safrole	Roots and other underground parts	Essential oil	≥ 10.17 Percent	GC-MS	Resolve DOI
Safrole	Roots and other underground parts	Essential oil	≤ 88.8 Percent	GC-MS	Resolve DOI
Safrole	Roots and other underground parts	Solvent extraction	84.96 Percent	GC-MS	Resolve DOI
(-)-camphor	Bark	Essential oil	≤ 5 Percent	GC-MS	No resolvable identifier
(-)-camphor	Bark	Essential oil	≥ 2 Percent	GC-MS	No resolvable identifier
1,8-cineole	Bark	Essential oil	≤ 10 Percent	GC-MS	No resolvable identifier
1,8-cineole	Bark	Essential oil	≥ 7 Percent	GC-MS	No resolvable identifier
Safrole	Roots and other underground parts	Solvent extraction	≤ 16 Milligram/gram	HPLC-DAD	No resolvable identifier
Safrole	Roots and other underground parts	Solvent extraction	≥ 0.13 Milligram/gram	HPLC-DAD	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Kamdem, DP., Gage, DA. Chemical composition of essential oil from the root bark of Sassafras albidum . Planta medica, 1995, vol. 61, no. 6, p. 574-575. DOI
Carlson, M., Thompson, RD. Liquid chromatographic determination of safrole in sassafras-derived herbal products . Journal of aoac international, 1997, vol. 80, no. 5, p. 1023-1028.
CHOWDHURY, BK., SETHI, ML., LLOYD, HA., KAPADIA, GJ. POTENTIAL CARCINOGENS .6. APORPHINE AND TETRAHYDROBENZYLISOQUINOLINE ALKALOIDS IN SASSAFRAS-ALBIDUM . Phytochemistry, 1976, vol. 15, no. 11, p. 1803-1804. DOI
Zwaving, J.H., Bos, R. Composition of the Essential Oil from the Root of Sassafras albidum (Nutt.) Nees. Journal of essential oil research, 1996, vol. 8, no. 2, p. 193-195. DOI
Kennedy, J. Erin., Dave, Purva C., Harbin, Lindsay N., Setzer, William N. Allelopathic potential of Sassafras albidum and Pinus taeda essential oils . Allelopathy journal, 2011, vol. 27, no. 1, p. 111-122.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature