Botanical species · safety record

Schisandra chinensis

The EFSA Compendium of Botanicals holds 4 constituent measurements and 1 genotoxicity assay for Schisandra chinensis. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Schisandra chinensis (Turcz.) Baill.

4Constituent measurements

1Safety records

4Cited sources

1,593Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 1,593 licensed products naming Schisandra chinensis as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Dry
Extract Type TBA
Fresh
decoction
fluid

Source material stated

Bark and buds
Berries
Berry
Berry (standardized extract)
Berry extract
Berry/Berries
Dried fruit
Dried ripe fruit

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Lignans, total	Live plants	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Lignans	Fruit unspecified	Solvent extraction	—	HPLC-UV	No resolvable identifier
Lignans, total	Aerial part of plants	Solvent extraction	≥ 11.7 Percent	Unspecified	No resolvable identifier
Lignans, total	Aerial part of plants	Solvent extraction	≤ 17.7 Percent	Unspecified	No resolvable identifier

Genotoxicity testing

Outcomes of genotoxicity assays as recorded in the source. A negative assay is a result under those test conditions, not a clearance.

Outcome	Endpoint	Test	Tested organism	Metabolic activation	Source
Positive	gene mutation	mammalian cell gene mutation assay	House mouse (as animal)	With and without	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Tang, Shu-Hong., He, Rong-Rong., Huang, Ting., Wang, Cong-Zhi., Cao, Yun-Feng., Zhang, Yang., Kurihara, Hiroshi. The protective effect of schisandra lignans on stress-evoked hepatic metastases of P815 tumor cells in restraint mice . Journal of ethnopharmacology, 2011, vol. 134, no. 1, p. 141-146. DOI
Hu, Yan-ping., Wang, Xin., Song, Jie., Zhang, Min., Wang, Xiu-wen., Li, Bo. Genotoxicity of Fructus Schisandrae Chinensis concoction. Aibian, jibian, tubian, 2009, p. 309-312.
Wang Bao-lian., Hu Jin-ping., Sheng Li., Chen Hui., Li Yan. Chemical-pharmacokinetic-pharmacodynamic fingerprints of Schisandra chinensis alcoholic extract . Yaoxue xuebao, 2013, vol. 48, no. 5, p. 734-740.
Yu, Jie., Liu, Peixun., Long, Wei., Zhao, Feng. Experimental study on isolation and purification of total lignans from Schisandra chinensis and the anti-tumor activity in vitro. Zhongguo yaoshi (wuhan, china), 2009, p. 1718-1720.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature