Botanical species · safety record

Schisandra sphenanthera

The EFSA Compendium of Botanicals holds 12 constituent measurements for Schisandra sphenanthera. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Schisandra sphenanthera Rehder & E.H.Wilson

12Constituent measurements
0Safety records
5Cited sources
26Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 26 licensed products naming Schisandra sphenanthera as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

  • Dry
  • decoction

Source material stated

  • Fruit
  • Fruit(s)
  • Ripe fruit(s)

What the records describe

Constituents measured

  • Schizantherin a4
  • Lignans3
  • Schizandrin a2
  • Schizandrin b2
  • Schisandrin1

Plant parts

  • Fruit unspecified8
  • Stem3
  • stalk3
  • Leaves1

Preparations

  • Solvent extraction9

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
LignansFruit unspecifiedSolvent extractionHPLC with standard detection methodsResolve DOI
Schizandrin aFruit unspecifiedSolvent extraction0.54 PercentLC-MSResolve DOI
Schizandrin bFruit unspecifiedSolvent extraction0.3 PercentLC-MSResolve DOI
Schizantherin aFruit unspecifiedSolvent extraction0.56 PercentLC-MSResolve DOI
Schizantherin aStem / stalkSolvent extraction≥ 0.04 PercentLC-MSResolve DOI
Schizantherin aLeavesSolvent extraction0.05 PercentLC-MSResolve DOI
Schizantherin aStem / stalkSolvent extraction≤ 0.05 PercentLC-MSResolve DOI
LignansFruit unspecifiedSolvent extractionNuclear Magnetic Resonance (NMR)No resolvable identifier
LignansStem / stalkSolvent extractionNuclear Magnetic Resonance (NMR)No resolvable identifier
SchisandrinFruit unspecified7.196 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)No resolvable identifier
Schizandrin aFruit unspecified59.065 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)No resolvable identifier
Schizandrin bFruit unspecified3.213 Milligram/gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Ren, Rong., Ci, Xin-Xin., Li, Hai-Zhou., Li, Hong-Mei., Luo, Guo-Jun., Li, Rong-Tao., Deng, Xu-Ming. New Dibenzocyclooctadiene Lignans from Schisandra sphenanthera and Their Pro-inflammatory Cytokine Inhibitory Activities. ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES, 2010, vol. 65, no. 2, p. 211-218.
  2. Gu, Wei., Wei, Nanyu., Wang, Zhezhi. LC analysis of lignans from Schisandra sphenanthera Rehd. et Wils.. CHROMATOGRAPHIA, 2008, vol. 67, no. 11-12, p. 979-983. DOI
  3. Liu, Haitao., Zhang, Jin., Li, Xingbo., Qi, Yaodong., Peng, Yong., Zhang, Bengang., Xiao, Peigen. Chemical analysis of twelve lignans in the fruit of Schisandra sphenanthera by HPLC-PAD-MS. PHYTOMEDICINE, 2012, vol. 19, no. 13, p. 1234-1241. DOI
  4. Liang, Cheng-Qin., Hu, Jing., Shi, Yi-Ming., Shang, Shan-Zhai., Du, Xue., Zhan, Rui., Xiong, Wen-Yong., Zhang, Hong-Bin., Xiao, Wei-Lie., Sun, Han-Dong. Schisphenlignans A-E: Five New Dibenzocyclooctadiene Lignans from Schisandra sphenanthera. CHEMICAL & PHARMACEUTICAL BULLETIN, 2013, vol. 61, no. 1, p. 96-100.
  5. Liu, Shao-jing., Li, Yan., Zhang, Ying., Wang, Xiao-ning., Yang, Li-bin. Quantitative analysis of three lignans in Schisandra sphenanthera Rehd. Et Wils and Schisandra chinensis Baill. by RP-HPLC. Yingyong huagong, 2014, p. 2107-2110.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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