Botanical species · safety record

Scoparia dulcis

The EFSA Compendium of Botanicals holds 8 constituent measurements and 4 adverse-effect records for Scoparia dulcis. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Scoparia dulcis L.

8Constituent measurements

4Safety records

4Cited sources

1Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 1 licensed products naming Scoparia dulcis as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Source material stated

Herb

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Labdane diterpenes	Aerial part of plants	—	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Labdane diterpenes	Aerial part of plants	—	—	Phytochemical screening	Resolve DOI
Alkaloids	Leaves	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Alkaloids	Aerial part of plants	Solvent extraction	≥ 0.48 Percent	Phytochemical screening	No resolvable identifier
Alkaloids	Aerial part of plants	Solvent extraction	≤ 1.14 Percent	Phytochemical screening	No resolvable identifier
Cardiac glycosides	Aerial part of plants	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Saponin glycosides	Leaves	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Tannins	Leaves	Solvent extraction	—	Phytochemical screening	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Hepatotoxicity	Liver	Leaves	Solvent extraction	House mouse (as animal)	Short-term toxicity	No resolvable identifier
Hepatotoxicity	Liver	Leaves	Solvent extraction	House mouse (as animal)	Short-term toxicity	No resolvable identifier
Pulmonary and cardiac	Heart	Leaves	Solvent extraction	House mouse (as animal)	Short-term toxicity	No resolvable identifier
Pulmonary and cardiac	Heart	Leaves	Solvent extraction	House mouse (as animal)	Short-term toxicity	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Abere Tavs A., Okoye Chiagozie J., Jesuorobo Rose I., Egharevba Clement O., Aimator Pauline O., Agoreyo Freddy O., Eze Gerald I. Antisickling and toxicological evaluation of the leaves of Scoparia dulcis Linn (Scrophulariaceae). BMC complementary and alternative medicine, 2015.
Edeoga, H. O., Okwu, D. E., Mbaebie, B. O. Phytochemical constituents of some Nigerian medicinal plants. African journal of biotechnology - online, 2005, p. 685-688.
Ahsan, M., Islam, SN., Gray, AI., Stimson, WH. Cytotoxic diterpenes from Scoparia dulcis. Journal of natural products, 2003, vol. 66, no. 7, p. 958-961. DOI
Fuentes, Rolly G., Toume, Kazufumi., Arai, Midori A., Sadhu, Samir K., Ahmed, Firoj., Ishibashi, Masami. Scopadulciol, Isolated from Scoparia dulcis, Induces beta-Catenin Degradation and Overcomes Tumor Necrosis Factor-Related Apoptosis Ligand Resistance in AGS Human Gastric Adenocarcinoma Cells. JOURNAL OF NATURAL PRODUCTS, 2015, vol. 78, no. 4, p. 864-872. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature