Botanical species · safety record
Sedum acre
The EFSA Compendium of Botanicals holds 21 constituent measurements and 1 adverse-effect record for Sedum acre. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Sedum acre L.
Regulatory presence
Health Canada's Licensed Natural Health Products Database holds 16 licensed products naming Sedum acre as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.
Source material stated
What the records describe
Constituents measured
- Piperidine alkaloids12
- 3,4-dihydroxybenzoic acid1
- 4-hydroxybenzoic acid1
- Alkaloids1
- Coumarins1
- Nicotine1
- P-coumaric acid1
- Pelletierine1
- Pseudopelletierine1
- Salicylic acid1
Plant parts
- Aerial part of plants11
- Unspecified6
- Live plants5
Preparations
- Solvent extraction21
Effect types
- Systemic1
Target tissues
- Neurologic1
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Alkaloids | Live plants | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Pelletierine | Aerial part of plants | Solvent extraction | ≤ 3 Percent | GC-MS | Resolve DOI |
| Piperidine alkaloids | Aerial part of plants | Solvent extraction | ≥ 23 Percent | GC-MS | Resolve DOI |
| Piperidine alkaloids | Aerial part of plants | Solvent extraction | ≤ 62 Percent | GC-MS | Resolve DOI |
| Piperidine alkaloids | Aerial part of plants | Solvent extraction | ≤ 66 Percent | GC-MS | Resolve DOI |
| Piperidine alkaloids | Aerial part of plants | Solvent extraction | ≥ 21 Percent | GC-MS | Resolve DOI |
| Piperidine alkaloids | Unspecified | Solvent extraction | — | GC-MS | Resolve DOI |
| Piperidine alkaloids | Aerial part of plants | Solvent extraction | ≤ 19 Percent | GC-MS | Resolve DOI |
| Piperidine alkaloids | Live plants | Solvent extraction | — | Standard Chromatographic tests (paper- thin layer- and column chromatography) | Resolve DOI |
| Piperidine alkaloids | Aerial part of plants | Solvent extraction | ≥ 1 Percent | GC-MS | Resolve DOI |
| Piperidine alkaloids | Aerial part of plants | Solvent extraction | ≤ 3 Percent | GC-MS | Resolve DOI |
| Piperidine alkaloids | Aerial part of plants | Solvent extraction | ≥ 9 Percent | GC-MS | Resolve DOI |
| Piperidine alkaloids | Aerial part of plants | Solvent extraction | ≤ 20 Percent | GC-MS | Resolve DOI |
| Pseudopelletierine | Aerial part of plants | Solvent extraction | 0.01 Percent | GC-MS | Resolve DOI |
| 3,4-dihydroxybenzoic acid | Unspecified | Solvent extraction | — | Chromatographic tests | No resolvable identifier |
| 4-hydroxybenzoic acid | Unspecified | Solvent extraction | — | Chromatographic tests | No resolvable identifier |
| Coumarins | Unspecified | Solvent extraction | — | Chromatographic tests | No resolvable identifier |
| Nicotine | Live plants | Solvent extraction | — | Traditional analytical techniques (wet chemical tests) | No resolvable identifier |
| P-coumaric acid | Unspecified | Solvent extraction | — | Chromatographic tests | No resolvable identifier |
| Piperidine alkaloids | Live plants | Solvent extraction | — | Traditional analytical techniques (wet chemical tests) | No resolvable identifier |
| Salicylic acid | Unspecified | Solvent extraction | — | Chromatographic tests | No resolvable identifier |
Recorded adverse effects
Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.
| Effect | Target tissue | Plant part | Preparation | Test organism | Test type | Source |
|---|---|---|---|---|---|---|
| Systemic | Neurologic | Live plants | — | — | Not reported | Resolve DOI |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- STEVENS, JF., THART, H., HENDRIKS, H., MALINGRE, TM. ALKALOIDS OF THE SEDUM ACRE-GROUP (CRASSULACEAE). Plant systematics and evolution, 1993, vol. 185, no. 3-4, p. 207-217. DOI
- Marion, Leo. The alkaloids of Sedum acre L. Canadian journal of research, section b: chemical sciences, 1945, vol. 23B, p. 165-6.
- Wolbis, Maria. Polyphenolic compounds in certain species of Sedum. I. Coumarins and phenolic acids in Sedum acre, Sedum album, and Sedum maximum. Acta poloniae pharmaceutica, 1987, vol. 44, no. 6, p. 563-6.
- MAKSIMOVIC, M., SOBER, M., NIKOLIN, B. GAS-CHROMATOGRAPHY MASS-SPECTROMETRY IN THE ELUCIDATION OF THE STRUCTURE OF PIPERIDINE ALKALOIDS . Rapid communications in mass spectrometry, 1990, vol. 4, no. 12, p. 503-504. DOI
- COLAU, B., HOOTELE, C. SEDUM ALKALOIDS .5. SEDACRINE, THE MAJOR ALKALOID OF SEDUM-ACRE, AND RELATED BASES . Canadian journal of chemistry-revue canadienne de chimie, 1983, vol. 61, no. 3, p. 470-472. DOI
- IBEBEKEBOMANGWA, W., HOOTELE, C. SEDUM ALKALOIDS .10. STRUCTURE AND SYNTHESIS OF NEW 3-HYDROXPIPERIDINE AND 5-HYDROXYPIPERIDINE ALKALOIDS . Tetrahedron, 1987, vol. 43, no. 5, p. 935-945. DOI
- Al-Qura'n, S. Ethnobotanical survey of folk toxic plants in southern part of Jordan. Toxicon, 2005, vol. 46, no. 2, p. 119-129. DOI
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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