Botanical species · safety record

Sedum acre

The EFSA Compendium of Botanicals holds 21 constituent measurements and 1 adverse-effect record for Sedum acre. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Sedum acre L.

21Constituent measurements
1Safety records
7Cited sources
16Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 16 licensed products naming Sedum acre as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Source material stated

  • Fresh aerial part collected at flowering time
  • Plante entière
  • Whole plant
  • Whole plant(s)

What the records describe

Constituents measured

  • Piperidine alkaloids12
  • 3,4-dihydroxybenzoic acid1
  • 4-hydroxybenzoic acid1
  • Alkaloids1
  • Coumarins1
  • Nicotine1
  • P-coumaric acid1
  • Pelletierine1
  • Pseudopelletierine1
  • Salicylic acid1

Plant parts

  • Aerial part of plants11
  • Unspecified6
  • Live plants5

Preparations

  • Solvent extraction21

Effect types

  • Systemic1

Target tissues

  • Neurologic1

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
AlkaloidsLive plantsSolvent extractionNuclear Magnetic Resonance (NMR)Resolve DOI
PelletierineAerial part of plantsSolvent extraction≤ 3 PercentGC-MSResolve DOI
Piperidine alkaloidsAerial part of plantsSolvent extraction≥ 23 PercentGC-MSResolve DOI
Piperidine alkaloidsAerial part of plantsSolvent extraction≤ 62 PercentGC-MSResolve DOI
Piperidine alkaloidsAerial part of plantsSolvent extraction≤ 66 PercentGC-MSResolve DOI
Piperidine alkaloidsAerial part of plantsSolvent extraction≥ 21 PercentGC-MSResolve DOI
Piperidine alkaloidsUnspecifiedSolvent extractionGC-MSResolve DOI
Piperidine alkaloidsAerial part of plantsSolvent extraction≤ 19 PercentGC-MSResolve DOI
Piperidine alkaloidsLive plantsSolvent extractionStandard Chromatographic tests (paper- thin layer- and column chromatography)Resolve DOI
Piperidine alkaloidsAerial part of plantsSolvent extraction≥ 1 PercentGC-MSResolve DOI
Piperidine alkaloidsAerial part of plantsSolvent extraction≤ 3 PercentGC-MSResolve DOI
Piperidine alkaloidsAerial part of plantsSolvent extraction≥ 9 PercentGC-MSResolve DOI
Piperidine alkaloidsAerial part of plantsSolvent extraction≤ 20 PercentGC-MSResolve DOI
PseudopelletierineAerial part of plantsSolvent extraction0.01 PercentGC-MSResolve DOI
3,4-dihydroxybenzoic acidUnspecifiedSolvent extractionChromatographic testsNo resolvable identifier
4-hydroxybenzoic acidUnspecifiedSolvent extractionChromatographic testsNo resolvable identifier
CoumarinsUnspecifiedSolvent extractionChromatographic testsNo resolvable identifier
NicotineLive plantsSolvent extractionTraditional analytical techniques (wet chemical tests)No resolvable identifier
P-coumaric acidUnspecifiedSolvent extractionChromatographic testsNo resolvable identifier
Piperidine alkaloidsLive plantsSolvent extractionTraditional analytical techniques (wet chemical tests)No resolvable identifier
Salicylic acidUnspecifiedSolvent extractionChromatographic testsNo resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

EffectTarget tissuePlant partPreparationTest organismTest typeSource
SystemicNeurologicLive plantsNot reportedResolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. STEVENS, JF., THART, H., HENDRIKS, H., MALINGRE, TM. ALKALOIDS OF THE SEDUM ACRE-GROUP (CRASSULACEAE). Plant systematics and evolution, 1993, vol. 185, no. 3-4, p. 207-217. DOI
  2. Marion, Leo. The alkaloids of Sedum acre L. Canadian journal of research, section b: chemical sciences, 1945, vol. 23B, p. 165-6.
  3. Wolbis, Maria. Polyphenolic compounds in certain species of Sedum. I. Coumarins and phenolic acids in Sedum acre, Sedum album, and Sedum maximum. Acta poloniae pharmaceutica, 1987, vol. 44, no. 6, p. 563-6.
  4. MAKSIMOVIC, M., SOBER, M., NIKOLIN, B. GAS-CHROMATOGRAPHY MASS-SPECTROMETRY IN THE ELUCIDATION OF THE STRUCTURE OF PIPERIDINE ALKALOIDS . Rapid communications in mass spectrometry, 1990, vol. 4, no. 12, p. 503-504. DOI
  5. COLAU, B., HOOTELE, C. SEDUM ALKALOIDS .5. SEDACRINE, THE MAJOR ALKALOID OF SEDUM-ACRE, AND RELATED BASES . Canadian journal of chemistry-revue canadienne de chimie, 1983, vol. 61, no. 3, p. 470-472. DOI
  6. IBEBEKEBOMANGWA, W., HOOTELE, C. SEDUM ALKALOIDS .10. STRUCTURE AND SYNTHESIS OF NEW 3-HYDROXPIPERIDINE AND 5-HYDROXYPIPERIDINE ALKALOIDS . Tetrahedron, 1987, vol. 43, no. 5, p. 935-945. DOI
  7. Al-Qura'n, S. Ethnobotanical survey of folk toxic plants in southern part of Jordan. Toxicon, 2005, vol. 46, no. 2, p. 119-129. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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