Botanical species · safety record

Sedum aizoon

The EFSA Compendium of Botanicals holds 14 constituent measurements and 1 adverse-effect record for Sedum aizoon. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Sedum aizoon L.

14Constituent measurements
1Safety records
7Cited sources
0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

  • Alkaloids2
  • Coumarins2
  • Tannins2
  • 3,4-dihydroxybenzoic acid1
  • 4-hydroxybenzoic acid1
  • Gallic acid1
  • Hydroquinone1
  • Isoflavones1
  • Naphthalene derivatives1
  • Piperidine alkaloids1

Plant parts

  • Aerial part of plants7
  • Roots and other underground parts4
  • Live plants2
  • Unspecified2

Preparations

  • Solvent extraction12

Effect types

  • Hepatotoxicity1

Target tissues

  • Liver1

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
3,4-dihydroxybenzoic acidAerial part of plantsSolvent extractionNuclear Magnetic Resonance (NMR)Resolve DOI
4-hydroxybenzoic acidAerial part of plantsSolvent extractionNuclear Magnetic Resonance (NMR)Resolve DOI
Gallic acidAerial part of plantsSolvent extractionNuclear Magnetic Resonance (NMR)Resolve DOI
IsoflavonesLive plantsSolvent extractionNuclear Magnetic Resonance (NMR)Resolve DOI
AlkaloidsAerial part of plantsSolvent extraction0.35 PercentPhytochemical screeningNo resolvable identifier
AlkaloidsRoots and other underground partsSolvent extraction0.2 PercentPhytochemical screeningNo resolvable identifier
CoumarinsRoots and other underground partsSolvent extraction0.3 PercentPhytochemical screeningNo resolvable identifier
CoumarinsAerial part of plantsSolvent extraction1.2 PercentPhytochemical screeningNo resolvable identifier
HydroquinoneLive plantsSolvent extractionStandard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier
Naphthalene derivativesUnspecifiedSolvent extractionUnspecifiedNo resolvable identifier
Piperidine alkaloidsAerial part of plantsChromatographic testsNo resolvable identifier
Pyrrolizidine alkaloidsRoots and other underground partsGC-MSNo resolvable identifier
TanninsAerial part of plantsSolvent extraction11.5 PercentPhytochemical screeningNo resolvable identifier
TanninsRoots and other underground partsSolvent extraction22.8 PercentPhytochemical screeningNo resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

EffectTarget tissuePlant partPreparationTest organismTest typeSource
HepatotoxicityLiverUnspecifiedHuman (as organism)Case reportNo resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Lin, Zhucan., Fang, Yingjuan., Huang, Anyu., Chen, Liyun., Guo, Suhua., Chen, Jianwei. Chemical constituents from Sedum aizoon and their hemostatic activity. Pharmaceutical biology, 2014, vol. 52, no. 11, p. 1429-1434. DOI
  2. Korul'kin, D. Yu. Chemical composition of certain Sedum species of Kazakhstan. Chemistry of Natural Compounds (Translation of Khimiya Prirodnykh Soedinenii), 2001, p. 219-223.
  3. Gao, Xinsheng., Xiao, Shaoshu., He, Jiangfu. Analysis of alkaloids in Sedum aizoon and establishment of hepatic veno-occlusive model in mice. Zhongguo zhongxiyi jiehe xiaohua zazhi, 2006, p. 311-313.
  4. Krasnov, E. A., Petrova, L. V., Bekker, E. F. Alkaloids of Sedum species. Khimiya prirodnykh soedinenii, 1977.
  5. Lin, Zhu-can., Huang, Hua-hua., Chen, Da-wei., Chen, Jian-wei., Guo, Su-hua. Study on chemical constituents of active parts of calming the heart and tranquilizing the mind from Sedum aizoon L.. Zhonghua zhongyiyao zazhi, 2011, p. 3000-3002.
  6. Li, Wei Lin., Luo, Qiu Yan., Wu, Li Qiang. Two new prenylated isoflavones from Sedum aizoon L.. Fitoterapia, 2011, vol. 82, no. 3, p. 405-407. DOI
  7. Wu, Guo-Lin., Yu, Guo-You., Chen, Jiu. Clinical analysis of hepatic veno-occlusive disease induced by Sedum aizoon . . Zhongguo zhong yao za zhi = zhongguo zhongyao zazhi = china journal of chinese materia medica, 2008, vol. 33, no. 20, p. 2402-4.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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