Botanical species · safety record
Sedum aizoon
The EFSA Compendium of Botanicals holds 14 constituent measurements and 1 adverse-effect record for Sedum aizoon. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Sedum aizoon L.
Regulatory presence
No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.
What the records describe
Constituents measured
- Alkaloids2
- Coumarins2
- Tannins2
- 3,4-dihydroxybenzoic acid1
- 4-hydroxybenzoic acid1
- Gallic acid1
- Hydroquinone1
- Isoflavones1
- Naphthalene derivatives1
- Piperidine alkaloids1
Plant parts
- Aerial part of plants7
- Roots and other underground parts4
- Live plants2
- Unspecified2
Preparations
- Solvent extraction12
Effect types
- Hepatotoxicity1
Target tissues
- Liver1
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| 3,4-dihydroxybenzoic acid | Aerial part of plants | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| 4-hydroxybenzoic acid | Aerial part of plants | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Gallic acid | Aerial part of plants | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Isoflavones | Live plants | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Alkaloids | Aerial part of plants | Solvent extraction | 0.35 Percent | Phytochemical screening | No resolvable identifier |
| Alkaloids | Roots and other underground parts | Solvent extraction | 0.2 Percent | Phytochemical screening | No resolvable identifier |
| Coumarins | Roots and other underground parts | Solvent extraction | 0.3 Percent | Phytochemical screening | No resolvable identifier |
| Coumarins | Aerial part of plants | Solvent extraction | 1.2 Percent | Phytochemical screening | No resolvable identifier |
| Hydroquinone | Live plants | Solvent extraction | — | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
| Naphthalene derivatives | Unspecified | Solvent extraction | — | Unspecified | No resolvable identifier |
| Piperidine alkaloids | Aerial part of plants | — | — | Chromatographic tests | No resolvable identifier |
| Pyrrolizidine alkaloids | Roots and other underground parts | — | — | GC-MS | No resolvable identifier |
| Tannins | Aerial part of plants | Solvent extraction | 11.5 Percent | Phytochemical screening | No resolvable identifier |
| Tannins | Roots and other underground parts | Solvent extraction | 22.8 Percent | Phytochemical screening | No resolvable identifier |
Recorded adverse effects
Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.
| Effect | Target tissue | Plant part | Preparation | Test organism | Test type | Source |
|---|---|---|---|---|---|---|
| Hepatotoxicity | Liver | Unspecified | — | Human (as organism) | Case report | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Lin, Zhucan., Fang, Yingjuan., Huang, Anyu., Chen, Liyun., Guo, Suhua., Chen, Jianwei. Chemical constituents from Sedum aizoon and their hemostatic activity. Pharmaceutical biology, 2014, vol. 52, no. 11, p. 1429-1434. DOI
- Korul'kin, D. Yu. Chemical composition of certain Sedum species of Kazakhstan. Chemistry of Natural Compounds (Translation of Khimiya Prirodnykh Soedinenii), 2001, p. 219-223.
- Gao, Xinsheng., Xiao, Shaoshu., He, Jiangfu. Analysis of alkaloids in Sedum aizoon and establishment of hepatic veno-occlusive model in mice. Zhongguo zhongxiyi jiehe xiaohua zazhi, 2006, p. 311-313.
- Krasnov, E. A., Petrova, L. V., Bekker, E. F. Alkaloids of Sedum species. Khimiya prirodnykh soedinenii, 1977.
- Lin, Zhu-can., Huang, Hua-hua., Chen, Da-wei., Chen, Jian-wei., Guo, Su-hua. Study on chemical constituents of active parts of calming the heart and tranquilizing the mind from Sedum aizoon L.. Zhonghua zhongyiyao zazhi, 2011, p. 3000-3002.
- Li, Wei Lin., Luo, Qiu Yan., Wu, Li Qiang. Two new prenylated isoflavones from Sedum aizoon L.. Fitoterapia, 2011, vol. 82, no. 3, p. 405-407. DOI
- Wu, Guo-Lin., Yu, Guo-You., Chen, Jiu. Clinical analysis of hepatic veno-occlusive disease induced by Sedum aizoon . . Zhongguo zhong yao za zhi = zhongguo zhongyao zazhi = china journal of chinese materia medica, 2008, vol. 33, no. 20, p. 2402-4.
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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