Botanical species · safety record

Senecio ovatus

The EFSA Compendium of Botanicals holds 1 constituent measurement, 1 adverse-effect record and 1 genotoxicity assay for Senecio ovatus. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Senecio ovatus Willd.

1Constituent measurements

2Safety records

3Cited sources

0Licensed products (Canada)

Also recorded as

Senecio nemorensis subsp. fuchsii (C.C.Gmel.) Ces.

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Pyrrolizidine alkaloids	Pollen-related	Solvent extraction	80 Microgram/gram	HPLC with standard detection methods	Resolve DOI

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Hepatotoxicity	Liver	—	Solvent extraction	Rat (as animal)	Chronic/long term toxicity	No resolvable identifier

Genotoxicity testing

Outcomes of genotoxicity assays as recorded in the source. A negative assay is a result under those test conditions, not a clearance.

Outcome	Endpoint	Test	Tested organism	Metabolic activation	Source
Positive	gene mutation	bacterial reverse mutation assay	Salmonella typhimurium (as organism)	With	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Boppre, Michael., Colegate, Steven M., Edgar, John A., Fischer, Ottmar W. Hepatotoxic pyrrolizidine alkaloids in pollen and drying-related implications for commercial processing of bee pollen. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2008, vol. 56, no. 14, p. 5662-5672. DOI
HABS, H., HABS, M., MARQUARDT, H., RODER, E., SCHMAHL, D., WIEDENFELD, H. CARCINOGENIC AND MUTAGENIC ACTIVITY OF AN ALKALOIDAL EXTRACT OF SENECIO-NEMORENSIS SSP FUCHSII . Arzneimittel-forschung/drug research, 1982, vol. 32-1, no. 2, p. 144-148.
POOL, BL. GENOTOXIC ACTIVITY OF AN ALKALOIDAL EXTRACT OF SENECIO-NEMORENSIS, SSP FUCHSII IN SALMONELLA-TYPHIMURIUM AND ESCHERICHIA-COLI-SYSTEMS . Toxicology, 1982, vol. 24, no. 3-4, p. 351-355. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature