Senna alata

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 3 licensed products naming Senna alata as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

What the records describe

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Genotoxicity testing

Outcomes of genotoxicity assays as recorded in the source. A negative assay is a result under those test conditions, not a clearance.

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

1. Veerachari, U., Bopaiah, A.K. Phytochemical investigation of the ethanol, methanol and ethyl acetate leaf extracts of six cassia species. International Journal of Pharma and Bio Sciences, 2012, vol. 3, no. 2, p. P260-P270.
2. Ogunkunle, A. T. J., Ladejobi, Tonia A. Ethnobotanical and phytochemical studies on some species of Senna in Nigeria. AFRICAN JOURNAL OF BIOTECHNOLOGY, 2006, vol. 5, no. 21, p. 2020-2023.
3. Abii, T. A., Onuha, E. N. A preliminary investigation into the phytochemicals, vitamins and mineral constituents of the leaf of two tradomedicinal plants - urena lobata and cassia alata used in Nigeria. IOSR Journal of Applied Chemistry, 2014, p. 1-4.
4. MT, Y., AO, A., AT, O., MA, A., OB, O., GA, J., AWO, O., AJ, A. Abortifacient Potential of Aqueous Extract of Senna alata Leaves in Rats. Journal of Reproduction and Contraception, 2010, vol. 21, no. 3, p. 163-177. DOI
5. Rahman, M. S., Hasan, A. J. M. Moynul., Ali, M. Y., Ali, M. U. An isoflavone from the leaves of Cassia alata. Bangladesh journal of scientific and industrial research, 2005, p. 287-290.
6. Fernand, Vivian E., Dinh, David T., Washington, Samuel J., Fakayode, Sayo O., Losso, Jack N., van Ravenswaay, Rick O., Warner, Isiah M. Determination of pharmacologically active compounds in root extracts of Cassia alata L. by use of high performance liquid chromatography. Talanta, 2008, p. 896-902.
7. Yakubu, Musa Toyin., Musa, Isah Fakai. Liver and kidney functional indices of pregnant rats following the administration of the crude alkaloids from Senna alata (Linn. Roxb) leaves. Iranian Journal of Toxicology, 2012, p. 615-625.
8. Hong, Chang-Eui., Lyu, Su-Yun. Genotoxicity detection of five medicinal plants in Nigeria. JOURNAL OF TOXICOLOGICAL SCIENCES, 2011, vol. 36, no. 1, p. 87-93. DOI
9. Ogunwande, I.A., Flamini, G., Cioni, P.L., Omikorede, O., Azeez, R.A., Ayodele, A.A., Kamil, Y.O. Aromatic plants growing in Nigeria: Essential oil constituents of Cassia alata (Linn.) Roxb. and Helianthus annuus L. Records of natural products, 2010, vol. 4, no. 4, p. 211-217.
10. Morinaga, Osamu., Uto, Takuhiro., Sakamoto, Seiichi., Putalun, Waraporn., Lhieochaiphant, Sorasak., Tanaka, Hiroyuki., Shoyama, Yukihiro. Development of eastern blotting technique for sennoside A and sennoside B using anti-sennoside A and anti-sennoside B monoclonal antibodies. Phytochemical Analysis, 2009, p. 154-158.
11. Morinaga, Osamu., Uto, Takuhiro., Sakamoto, Seiichi., Tanaka, Hiroyuki., Shoyama, Yukihiro. Enzyme-linked immunosorbent assay for total sennosides using anti-sennoside A and anti-sennoside B monoclonal antibodies. Fitoterapia, 2009, p. 28-31.

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