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Botanical species · safety record

Simarouba amara

The EFSA Compendium of Botanicals holds 13 constituent measurements for Simarouba amara. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Simarouba amara Aubl.

13Constituent measurements
0Safety records
7Cited sources
0Licensed products (Canada)

Also recorded as

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

  • Alkaloids3
  • Coumarins2
  • Quassinoids2
  • Saponins2
  • Calcium oxalate1
  • Canthin-6-one1
  • Cardiac glycosides1
  • Phytic acid1

Plant parts

  • Leaves5
  • Seed4
  • Roots and other underground parts2
  • Wood2

Preparations

  • Solvent extraction12
  • Fresh1

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
AlkaloidsRoots and other underground partsSolvent extraction—Traditional analytical techniques (wet chemical tests)Resolve DOI
AlkaloidsSeedSolvent extraction1.01 Gram/100 gramColorimetry, Spectroscopy (Spectrometry) and PhotometryResolve DOI
Canthin-6-oneWoodSolvent extraction—Nuclear Magnetic Resonance (NMR)Resolve DOI
CoumarinsWoodSolvent extraction—Nuclear Magnetic Resonance (NMR)Resolve DOI
Phytic acidSeedSolvent extraction0.73 Gram/100 gramPhytochemical screeningResolve DOI
QuassinoidsRoots and other underground partsSolvent extraction—High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
QuassinoidsSeedSolvent extraction—Nuclear Magnetic Resonance (NMR)Resolve DOI
SaponinsSeedSolvent extraction3.7 Gram/100 gramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
AlkaloidsLeavesSolvent extraction—Phytochemical screeningNo resolvable identifier
Calcium oxalateLeavesFresh—Microscopic detectionNo resolvable identifier
Cardiac glycosidesLeavesSolvent extraction—Phytochemical screeningNo resolvable identifier
CoumarinsLeavesSolvent extraction—Phytochemical screeningNo resolvable identifier
SaponinsLeavesSolvent extraction—Phytochemical screeningNo resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Awate, P.D., Gaikwad, D.K. Influence of Growth Regulators on Secondary Metabolites of Medicinally Important Oil Yielding Plant <i>Simarouba glauca</i> DC. under Water Stress Conditions . Journal of stress physiology & biochemistry, 2014, vol. 10, no. 1, p. 222-229.
  2. LASSAK, EV., POLONSKY, J., JACQUEMIN, H. 5-HYDROXYCANTHIN-6-ONE FROM SIMAROUBA-AMARA. Phytochemistry, 1977, vol. 16, no. 7, p. 1126-1127. DOI
  3. Govindaraju, K., Darukeshwara, J., Srivastava, Alok K. Studies on protein characteristics and toxic constituents of Simarouba glauca oilseed meal . Food and chemical toxicology, 2009, vol. 47, no. 6, p. 1327-1332. DOI
  4. Shantha, T. R., Prathapa, Reddy M., Rama, Rao V., Kishore, Kumar R., Bhat, Sulochana. Pharmacognostical studies on the leaves of Lakshmitaru (Simarouba glauca DC.), a well known anti-cancerous plant. World journal of pharmacy and pharmaceutical sciences, 2016, vol. 5, no. 9, p. 1717-1727.
  5. Rivero-Cruz, JF., Lezutekong, R., Lobo-Echeverri, T., Ito, A., Mi, QW., Chai, HB., Soejarto, DD., Cordell, GA., Pezzuto, JM., Swanson, SM., More, I., Kinghorn, AD. Cytotoxic constituents of the twigs of Simaroubla glauca collected from a plot in southern Florida . Phytotherapy research, 2005, vol. 19, no. 2, p. 136-140. DOI
  6. Dou, JH., Khan, IA., McChesney, JD., Burandt, CL. Qualitative and quantitative high performance liquid chromatographic analysis of quassinoids in Simaroubaceae plants . Phytochemical analysis, 1996, vol. 7, no. 4, p. 192-200. DOI
  7. BHATNAGAR, S., POLONSKY, J., PRANGE, T., PASCARD, C. NEW TOXIC QUASSINOID GLUCOSIDES FROM SIMAROUBA-GLAUCA - X-RAY-ANALYSIS. Tetrahedron letters, 1984, vol. 25, no. 3, p. 299-302. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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