Botanical species · safety record

Smallanthus sonchifolius

The EFSA Compendium of Botanicals holds 9 constituent measurements and 2 adverse-effect records for Smallanthus sonchifolius. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Smallanthus sonchifolius (Poepp.) H.Rob.

9Constituent measurements

2Safety records

5Cited sources

99Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 99 licensed products naming Smallanthus sonchifolius as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Dry
Fresh

Source material stated

Leaf
New material
Root
Root (powder)
Tuber

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Oxalic acid	Roots and other underground parts	Solvent extraction	≤ 914 Milligram/kilogram	Traditional analytical techniques (wet chemical tests)	Resolve DOI
Oxalic acid	Roots and other underground parts	Solvent extraction	≥ 416 Milligram/kilogram	Traditional analytical techniques (wet chemical tests)	Resolve DOI
Sesquiterpene lactones	Leaves	Solvent extraction	—	GC-MS	Resolve DOI
Sesquiterpene lactones	Leaves	Solvent extraction	—	Unspecified	Resolve DOI
Sesquiterpene lactones	Leaves	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Alkaloids	Roots and other underground parts	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Alkaloids	Leaves	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Sesquiterpene lactones	Leaves	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Sesquiterpene lactones	Roots and other underground parts	Solvent extraction	—	Phytochemical screening	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Nephrotoxicity	Urogenital: kidneys	Leaves	Solvent extraction	Rat (as animal)	Subchronic	Resolve DOI
Nephrotoxicity	Urogenital: kidneys	Leaves	Solvent extraction	Rat (as animal)	Subchronic	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

de Oliveira, Rejane Barbosa., Chagas de Paula, Daniela Aparecida., Rocha, Bruno Alves., Franco, Joao Jose., Gobbo-Neto, Leonardo., Uyemura, Sergio Akira., dos Santos, Wagner Ferreira., Da Costa, Fernando Batista. Renal toxicity caused by oral use of medicinal plants: The yacon example. JOURNAL OF ETHNOPHARMACOLOGY, 2011, vol. 133, no. 2, p. 434-441. DOI
Ribeiro Pereira, Juciane de Abreu., Piccolo Barcelos, Maria de Fatima., De Angelis Pereira, Michel Cardoso., Ferreira, Eric Batista. Studies of chemical and enzymatic characteristics of Yacon (Smallanthus sonchifolius) and its flours. FOOD SCIENCE AND TECHNOLOGY, 2013, vol. 33, no. 1, p. 75-83. DOI
Reyes, Charisse T., Villiagen, Robbie-Charles P., Rodriguez, Evelyn B. Phytochemical Screening and Assessment of Health-Related Bioactivities of Phenolic Compounds from Yacon Smallanthus sonchifolius (Poepp. and Endl.) H. Robinson Leaves and Tubers . Philippine journal of crop science, 2014, vol. 39, no. 2, p. 1-11.
Serra Barcellona, Carolina., Marcelino Cabrera, Wilfredo., Maris Honore, Stella., Ines Mercado, Maria., Serafina Sanchez, Sara., Beatriz Genta, Susana. Safety assessment of aqueous extract from leaf Smallanthus sonchifolius and its main active lactone, enhydrin . Journal of ethnopharmacology, 2012, vol. 144, no. 2, p. 362-370. DOI
Siriwan, D., Miyawaki, C., Miyamoto, T., Naruse, T., Okazaki, K., Tamura, H. Chemopreventive activity of Sesquiterpene Lactones (SLs) from yacon against TPA-induced Raji cells deformation. Pakistan Journal of Biological Sciences, 2011, vol. 14, no. 10, p. 605-609. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature