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Botanical species · safety record

Solanum dulcamara

The EFSA Compendium of Botanicals holds 11 constituent measurements and 3 adverse-effect records for Solanum dulcamara. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Solanum dulcamara L.

11Constituent measurements
3Safety records
6Cited sources
22Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 22 licensed products naming Solanum dulcamara as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Source material stated

  • Flower
  • Fresh shoot(s)
  • Fresh shoots collected prior to flowering
  • Green stems and leaves just before flowering
  • Jeune brindille fleurissante
  • Leaf/Leaves
  • Leaves before flowering
  • Parties aériennes fraîches récoltées au moment de la floraison

What the records describe

Constituents measured

  • Alpha-solamarine2
  • Solamargine2
  • Solasodine2
  • Solasonine2
  • Alpha-solanine1
  • Soladulcidine1
  • Steroidal alkaloids1

Plant parts

  • Fruit unspecified6
  • Leaves3
  • Stem2
  • stalk2
  • Aerial part of plants1
  • Unspecified1

Preparations

  • Solvent extraction11

Effect types

  • Irritation1
  • Neurotoxicity1
  • Systemic1

Target tissues

  • Heart1
  • Neurologic: central nervous system1
  • Skin1
  • subcutis1

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
Alpha-solanineUnspecified———Resolve DOI
Alpha-solamarineLeavesSolvent extraction——No resolvable identifier
Alpha-solamarineFruit unspecifiedSolvent extraction—Standard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier
SoladulcidineStem / stalkSolvent extraction——No resolvable identifier
SolamargineFruit unspecifiedSolvent extraction—Standard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier
SolamargineLeavesSolvent extraction——No resolvable identifier
SolasodineStem / stalkSolvent extraction——No resolvable identifier
SolasodineFruit unspecifiedSolvent extraction—Standard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier
SolasonineFruit unspecifiedSolvent extraction—Standard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier
SolasonineLeavesSolvent extraction——No resolvable identifier
Steroidal alkaloidsFruit unspecifiedSolvent extraction—Standard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

EffectTarget tissuePlant partPreparationTest organismTest typeSource
IrritationSkin/subcutis—Solvent extractionHuman (as organism)Case reportResolve DOI
SystemicHeartFruit unspecified—Human (as organism)Case reportResolve DOI
NeurotoxicityNeurologic: central nervous systemAerial part of plants—Dog (as animal)Case reportNo resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Calapai, Gioacchino., Minciullo, Paola L., Miroddi, Marco., Chinou, Ioanna., Gangemi, Sebastiano., Schmidt, Richard J. Contact dermatitis as an adverse reaction to some topically used European herbal medicinal products - Part 3: Mentha x piperita - Solanum dulcamara . Contact dermatitis, 2016, vol. 74, no. 3, p. 131-144. DOI
  2. Kees, Megan., Beckel, Nicole., Sharp, Claire. Successful treatment of Solanum dulcamara intoxication in a Labrador retriever puppy . Canadian veterinary journal-revue veterinaire canadienne, 2015, vol. 56, no. 12, p. 1283-1286.
  3. Ceha, L. J., Presperin, C., Young, E., Allswede, M., Erickson, T. Anticholinergic toxicity from nightshade berry poisoning responsive to physostigmine. Journal of Emergency Medicine, 1997, vol. 15, no. 1, p. 65-69. DOI
  4. Valovics, N. A., Bartok, Mrs. Antal. Determination of solasodine, soladulcidine, and tomatidenol in Solanum dulcamara. Herba hungarica, 1969, vol. 8, no. 3, p. 107-11.
  5. Boll, Per M., Andersen, Birte. Alkaloidal glycosides from Solanum dulcamara. III. Differentiation of geographical strains by means of thin-layer chromatography. Planta medica, 1962, vol. 10, p. 421-32.
  6. Bradberry, S., Vale, A. Plants. Medicine (united kingdom), 2016, vol. 44, no. 2, p. 113-115. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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