Botanical species · safety record

Solanum glaucophyllum

The EFSA Compendium of Botanicals holds 3 constituent measurements and 21 adverse-effect records for Solanum glaucophyllum. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Solanum glaucophyllum Desf.

3Constituent measurements

21Safety records

10Cited sources

0Licensed products (Canada)

Also recorded as

Solanum malacoxylon Sendtn.

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Alpha-solanine	Unspecified	—	—	Unspecified	No resolvable identifier
Estrone	Unspecified	—	—	Unspecified	No resolvable identifier
Solamargine	Unspecified	—	—	Unspecified	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Digestive	Stomach	Leaves	Solvent extraction	Rabbit (as animal)	Short-term toxicity	Resolve DOI
Digestive	Digestive	Leaves	Powder	Rabbit (as animal)	Short-term toxicity	Resolve DOI
Musclo-skeletal	Bone (deprecated)	Leaves	Powder	Rabbit (as animal)	Short-term toxicity	Resolve DOI
Other toxicities	Skin/subcutis	Leaves	Powder	Cattle (as animal)	Short-term toxicity	Resolve DOI
Pulmonary and cardiac	Lung	Leaves	Solvent extraction	Rabbit (as animal)	Short-term toxicity	Resolve DOI
Reproductive	Uterus	Leaves	Powder	Rabbit (as animal)	Reproduction toxicity	Resolve DOI
Reproductive	Uterus	Leaves	Powder	Rabbit (as animal)	Reproduction toxicity	Resolve DOI
Reproductive	Lung	Leaves	Powder	Rat (as animal)	Reproduction toxicity	Resolve DOI
Reproductive	Uterus	Leaves	Powder	Rat (as animal)	Reproduction toxicity	Resolve DOI
Systemic	Heart	Leaves	Powder	Cattle (as animal)	Short-term toxicity	Resolve DOI
Systemic	Muscle, skeletal	Leaves	Solvent extraction	Rabbit (as animal)	Short-term toxicity	Resolve DOI
Systemic	Neurologic	Unspecified	—	Cattle (as animal)	Case report	Resolve DOI
Systemic	Digestive	Leaves	Powder	Cattle (as animal)	Short-term toxicity	Resolve DOI
Teratogenic	Bone (deprecated)	Leaves	Powder	Rat (as animal)	Reproduction toxicity	Resolve DOI
Teratogenic	Bone (deprecated)	Leaves	Powder	Rat (as animal)	Reproduction toxicity	Resolve DOI
Immunotoxicity	Neurologic	Leaves	Powder	Cattle (as animal)	Other	No resolvable identifier
Musclo-skeletal	Bone (deprecated)	Leaves	Powder	Pig (as animal)	Short-term toxicity	No resolvable identifier
Musclo-skeletal	Bone (deprecated)	Leaves	Powder	Pig (as animal)	Short-term toxicity	No resolvable identifier
Pulmonary and cardiac	Heart	Leaves	Powder	Pig (as animal)	Short-term toxicity	No resolvable identifier
Pulmonary and cardiac	Heart	Leaves	Powder	Pig (as animal)	Short-term toxicity	No resolvable identifier
Systemic	Cardiovascular / haematological	Leaves	Powder	Cattle (as animal)	Short-term toxicity	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Gorniak, SL., Maiorka, PC., Raspantini, PC., Hosomi, R., Moraes, AP., Dagli, MLZ. Assessment of the perinatal effects of maternal ingestion of Solanum malacoxylon in rats . Reproductive toxicology, 2003, vol. 17, no. 1, p. 67-72. DOI
Fontana, Paula A., Zanuzzi, Carolina N., Barbeito, Claudio G., Gimeno, Eduardo J., Portiansky, Enrique L. Thymic atrophy in cattle poisoned with Solanum glaucophyllum. Pesquisa veterinaria brasileira, 2009, vol. 29, no. 3, p. 266-274.
DONE, SH., TOKARNIA, CH., DAMMRICH, K., DOBEREINER, J. SOLANUM-MALACOXYLON POISONING IN PIGS. Research in veterinary science, 1976, vol. 20, no. 2, p. 217-219.
Gimeno, EJ., Costa, EF., Gomar, MS., Massone, AR., Portiansky, EL. Effects of plant-induced hypervitaminosis D on cutaneous structure, cell differentiation and cell proliferation in cattle . Journal of veterinary medicine series a-physiology pathology clinical medicine, 2000, vol. 47, no. 4, p. 201-211. DOI
Dallorso, ME., Gil, S., Pawlak, E., Lema, F., Marquez, A. 1,25(OH)(2) vitamin D concentration in the plasma of Solanum glaucophyllum intoxicated rabbits . Australian veterinary journal, 2001, vol. 79, no. 6, p. 419-423. DOI
Garcia, Juan A., Canton, German J., Garcia, Bernardo L., Micheloud, Juan F., Campero, Carlos M., Spath, Ernesto J. A., Odriozola, Ernesto R. Retrospective analysis of cattle poisoning in Argentina (2000-2013). Pesquisa veterinaria brasileira, 2017, vol. 37, no. 3, p. 210-214. DOI
Aguirre, JI., Gomar, MS., Igal, S., Quiroga, MA., Portiansky, EL., Gimeno, EJ. Bone changes caused by,experimental Solanum malacoxylon poisoning in rabbits . Pesquisa veterinaria brasileira, 2005, vol. 25, no. 1, p. 34-38. DOI
Pomilio, A.B., Falzoni, E.M., Vitale, A.A. Toxic chemical compounds of the Solanaceae. Natural product communications, 2008, vol. 3, no. 4, p. 593-628.
Gorniak, SL., Dagli, MLZ., Maiorka, PC., Raspantini, PC., Jerico, MM. Evaluation in rabbits of the fetal effects of maternal ingestion of Solanum malacoxylon . Veterinary research communications, 1999, vol. 23, no. 5, p. 307-316. DOI
Zanuzzi, C. N., Barbeito, C. G., Ortiz, M. L., Lozza, F. A., Fontana, P. A., Portiansky, E. L., Gimeno, E. J. Glycoconjugate histochemistry in the small and large intestine of normal and Solanum glaucophyllum-intoxicated rabbits . Research in veterinary science, 2010, vol. 89, no. 2, p. 214-222. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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