Botanical species · safety record

Solanum lycopersicum

The EFSA Compendium of Botanicals holds 20 constituent measurements, 1 adverse-effect record and 2 genotoxicity assays for Solanum lycopersicum. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Solanum lycopersicum L.

20Constituent measurements
3Safety records
4Cited sources
600Licensed products (Canada)

Also recorded as

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 600 licensed products naming Solanum lycopersicum as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

  • Dry
  • Fresh

Source material stated

  • Edible fruit part
  • Fresh fruit
  • Fruit
  • Fruit Powder
  • Fruit flesh
  • Fruit flesh extract - standardized
  • Fruit(s)
  • Fruits

What the records describe

Constituents measured

  • Steroidal alkaloids20

Plant parts

  • Fruit unspecified5
  • Leaves5
  • Stem5
  • stalk5
  • Flower2
  • Flowering top2
  • Roots and other underground parts2

Preparations

  • Solvent extraction1

Effect types

  • Systemic1

Target tissues

  • Digestive1

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
Steroidal alkaloidsFruit unspecified≥ 144 Milligram/kilogramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
Steroidal alkaloidsFruit unspecified≤ 465 Milligram/kilogramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
Steroidal alkaloidsLeaves≥ 975 Milligram/kilogramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
Steroidal alkaloidsLeaves≤ 4900 Milligram/kilogramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
Steroidal alkaloidsRoots and other underground parts118 Milligram/kilogramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
Steroidal alkaloidsStem / stalk≥ 465 Milligram/kilogramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
Steroidal alkaloidsStem / stalk≤ 896 Milligram/kilogramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
Steroidal alkaloidsFlower≥ 7.3 PercentHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
Steroidal alkaloidsFlower≤ 15 PercentHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
Steroidal alkaloidsFruit unspecified≥ 8.8 PercentHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
Steroidal alkaloidsFruit unspecified≤ 10 PercentHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
Steroidal alkaloidsLeavesResolve DOI
Steroidal alkaloidsFruit unspecified< 500 Milligram/kilogramResolve DOI
Steroidal alkaloidsRoots and other underground parts23 PercentHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
Steroidal alkaloidsStem / stalk≤ 25 PercentHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
Steroidal alkaloidsStem / stalk≥ 13 PercentHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
Steroidal alkaloidsLeaves≤ 6.9 PercentHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
Steroidal alkaloidsLeaves≥ 6.1 PercentHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
Steroidal alkaloidsFlowering top≥ 795 Milligram/kilogramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
Steroidal alkaloidsFlowering top≤ 1100 Milligram/kilogramHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

EffectTarget tissuePlant partPreparationTest organismTest typeSource
SystemicDigestiveStem / stalkSolvent extractionGuinea pig (as animal)Acute toxicityNo resolvable identifier

Genotoxicity testing

Outcomes of genotoxicity assays as recorded in the source. A negative assay is a result under those test conditions, not a clearance.

OutcomeEndpointTestTested organismMetabolic activationSource
PositiveDNA damage and/or repairMammalian erythrocyte micronucleus testHouse mouse (as animal)No dataNo resolvable identifier
Positivechromosome aberrationchromosome aberration assayHouse mouse (as animal)No dataNo resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Silva, RMG., Figueiredo, CCM., Gomes, AD., de Mello Peixoto, ECT., Ferreira, PC., Silva, LP. MUTAGENICITY, ANTIOXIDANT ACTIVITY AND NUTRITIONAL CONTENT OF LONG-LIFE TOMATO. Bioscience journal, 2016, vol. 32, no. 4, p. 999-1007.
  2. Vianney, Ntabaza Ndage., Salvius, Bakari Amuri., Faustin, Mwamba Maseho., Joel, Kabadi Kasongo., Tresor, Sumbu Nzuki., Jean-Marie, Ompey Vianney., Jean-Baptiste, Lumbu Simbi., Byanga, Kahumba. Acute oral toxicity profile of the aqueous extract of six plants used in congolese traditional medicine. International journal of pharmacy and pharmaceutical research, 2019, vol. 15, no. 2, p. 168-181.
  3. Friedman, M. Analysis of biologically active compounds in potatoes (Solanum tuberosum), tomatoes (Lycopersicon esculentum), and jimson weed (Datura stramonium) seeds. Journal of chromatography a, 2004, vol. 1054, no. 1-2, p. 143-155. DOI
  4. Friedman M. Chemistry and anticarcinogenic mechanisms of glycoalkaloids produced by eggplants, potatoes, and tomatoes.. Journal of agricultural and food chemistry, 2015, vol. 63, no. 13, p. 3323-37. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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