Botanical species · safety record

Solidago canadensis

The EFSA Compendium of Botanicals holds 9 constituent measurements and 1 adverse-effect record for Solidago canadensis. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Solidago canadensis L.

9Constituent measurements
1Safety records
6Cited sources
17Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 17 licensed products naming Solidago canadensis as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

  • Dry
  • Fresh

Source material stated

  • Flowering herb
  • Flowering tops
  • Fresh flowering tops/aerial parts
  • Grass(es)
  • Herb top
  • Herb top flowering
  • New material
  • Solidago canadensis - Herb top flowering

What the records describe

Constituents measured

  • Clerodane-type diterpenes3
  • Labdane diterpenes2
  • Quinoline alkaloids2
  • Epoxides1
  • Polyacetylene derivatives1

Plant parts

  • Aerial part of plants4
  • Roots and other underground parts4
  • Leaves1
  • Unspecified1

Preparations

  • Solvent extraction9

Effect types

  • Systemic1

Target tissues

  • Stomach1

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
Clerodane-type diterpenesAerial part of plantsSolvent extractionNuclear Magnetic Resonance (NMR)Resolve DOI
Clerodane-type diterpenesAerial part of plantsSolvent extractionNuclear Magnetic Resonance (NMR)Resolve DOI
EpoxidesLeavesSolvent extraction1.1 PercentGC-MSResolve DOI
Labdane diterpenesRoots and other underground partsSolvent extractionNuclear Magnetic Resonance (NMR)Resolve DOI
Labdane diterpenesRoots and other underground partsSolvent extractionNuclear Magnetic Resonance (NMR)Resolve DOI
Clerodane-type diterpenesRoots and other underground partsSolvent extractionColorimetry, Spectroscopy (Spectrometry) and PhotometryNo resolvable identifier
Polyacetylene derivativesRoots and other underground partsSolvent extractionColorimetry, Spectroscopy (Spectrometry) and PhotometryNo resolvable identifier
Quinoline alkaloidsAerial part of plantsSolvent extractionNuclear Magnetic Resonance (NMR)No resolvable identifier
Quinoline alkaloidsAerial part of plantsSolvent extractionNuclear Magnetic Resonance (NMR)No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

EffectTarget tissuePlant partPreparationTest organismTest typeSource
SystemicStomachUnspecifiedHorse (as animal)Case reportNo resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Chizzola, R., Brandstaetter, M. Case report: possible causality between ingested Canadian golden rod and colic signs and successive mortality in horses . Wiener tierarztliche monatsschrift, 2006, vol. 93, no. 7-8, p. 166-169.
  2. Zeng, Zhi-Xin., Ma, Wen-Hui., Li, Yong-Le., Han, Ting., Zheng, Cheng-Jian., Qin, Lu-Ping. Two New Diterpenes from Solidago canadensis. HELVETICA CHIMICA ACTA, 2012, vol. 95, no. 7, p. 1121-1125. DOI
  3. LU, TS., MENELAOU, MA., VARGAS, D., FRONCZEK, FR., FISCHER, NH. POLYACETYLENES AND DITERPENES FROM SOLIDAGO-CANADENSIS. Phytochemistry, 1993, vol. 32, no. 6, p. 1483-1488.
  4. Li, Ying-Ke., Zhao, Qing-Jie., Hu, Jiang., Zou, Zui., He, Xing-Ying., Yuan, Hong-Bin., Shi, Xue-Yin. Two New Quinoline Alkaloid Mannopyranosides from Solidago canadensis. HELVETICA CHIMICA ACTA, 2009, vol. 92, no. 5, p. 928-931.
  5. Wangensteen, Helle., Phan, Thi T., Rise, Frode., Halvorsen, Trine G., Malterud, Karl E. New labdane diterpenes from Solidago canadensis. NATURAL PRODUCT RESEARCH, 2012, vol. 26, no. 14, p. 1348-1354. DOI
  6. Li, Deqiang., Pan, Shenghao., Zhu, Xiwu., Tan, Lin., Cao, Yuefen. Anticancer Activity and Chemical Composition of Leaf Essential Oil from Solidago canadensis L. in China. RENEWABLE AND SUSTAINABLE ENERGY, PTS 1-7, 2012, vol. 347-353, p. 1584-1589. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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