Botanical species · safety record

Spigelia anthelmia

The EFSA Compendium of Botanicals holds 7 constituent measurements and 1 adverse-effect record for Spigelia anthelmia. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Spigelia anthelmia L.

7Constituent measurements
1Safety records
3Cited sources
79Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 79 licensed products naming Spigelia anthelmia as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Source material stated

  • Aerial parts of the plant
  • Dried aerial part(s)
  • Dried aerial parts
  • Plante entière
  • Root
  • Spigelia anthelmia L., dried aerial parts
  • Tincture of the whole plant
  • Whole plant

What the records describe

Constituents measured

  • Alkaloids1
  • Cardiac glycosides1
  • Phlobotannins1
  • Ryanodine1
  • Saponins1
  • Spiganthine1
  • Tannins1

Plant parts

  • Aerial part of plants8

Preparations

  • Solvent extraction8

Effect types

  • Pulmonary and cardiac1

Target tissues

  • Respiratory1

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
RyanodineAerial part of plantsSolvent extractionNuclear Magnetic Resonance (NMR) and Electron Spin Resonance (ESR) spectroscopyResolve DOI
SpiganthineAerial part of plantsSolvent extractionNuclear Magnetic Resonance (NMR) and Electron Spin Resonance (ESR) spectroscopyResolve DOI
AlkaloidsAerial part of plantsSolvent extraction0.84 PercentPhytochemical screeningNo resolvable identifier
Cardiac glycosidesAerial part of plantsSolvent extractionPhytochemical screeningNo resolvable identifier
PhlobotanninsAerial part of plantsSolvent extractionPhytochemical screeningNo resolvable identifier
SaponinsAerial part of plantsSolvent extraction2.26 PercentPhytochemical screeningNo resolvable identifier
TanninsAerial part of plantsSolvent extraction15.05 PercentPhytochemical screeningNo resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

EffectTarget tissuePlant partPreparationTest organismTest typeSource
Pulmonary and cardiacRespiratoryAerial part of plantsSolvent extractionHouse mouse (as animal)Acute toxicityNo resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Edeoga, HO., Okwu, DE., Mbaebie, BO. Phytochemical constituents of some Nigerian medicinal plants. AFRICAN JOURNAL OF BIOTECHNOLOGY, 2005, vol. 4, no. 7, p. 685-688.
  2. Camurca-Vasconcelos, ALF., Nascimento, NRF., Sousa, CM., Melo, LM., Morais, SM., Bevilaqua, CML., Rocha, MFG. Neuromuscular effects and acute toxicity of an ethyl acetate extract of Spigelia anthelmia Linn. . Journal of ethnopharmacology, 2004, vol. 92, no. 2-3, p. 257-261.
  3. ACHENBACH, H., HUBNER, H., VIERLING, W., BRANDT, W., REITER, M. CONSTITUENTS OF TROPICAL MEDICINAL-PLANTS .68. SPIGANTHINE, THE CARDIOACTIVE PRINCIPLE OF SPIGELIA-ANTHELMIA . Journal of natural products-lloydia, 1995, vol. 58, no. 7, p. 1092-1096. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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