Botanical species · safety record

Stryphnodendron adstringens

The EFSA Compendium of Botanicals holds 6 constituent measurements, 2 adverse-effect records and 1 genotoxicity assay for Stryphnodendron adstringens. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Stryphnodendron adstringens (Mart.) Coville

6Constituent measurements

3Safety records

7Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Proanthocyanidins (condensed tannins)	Bark	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Tannins	Bark	Solvent extraction	19 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Tannins	Bark	Solvent extraction	≤ 30.8 Percent	Colorimetry, Spectroscopy (Spectrometry) and Photometry	Resolve DOI
Tannins	Bark	Solvent extraction	≥ 10.4 Percent	Colorimetry, Spectroscopy (Spectrometry) and Photometry	Resolve DOI
Proanthocyanidins (condensed tannins)	Bark	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Tannins	Bark	—	—	—	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Digestive	Digestive: pancreas	Bark	Solvent extraction	—	In vitro	Resolve DOI
Digestive	Digestive: pancreas	Bark	Solvent extraction	—	In vitro	Resolve DOI

Genotoxicity testing

Outcomes of genotoxicity assays as recorded in the source. A negative assay is a result under those test conditions, not a clearance.

Outcome	Endpoint	Test	Tested organism	Metabolic activation	Source
Positive	DNA damage and/or repair	SOS/umu test	Escherichia coli (as organism)	With and without	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Lopes, G.C., Sanches, A.C.C., De Toledo, C.E.M., Isler, A.C., De Mello, J.C.P. Quantitative determination of tannins in three species of Stryphnodendron by high-performance liquid chromatography Determina��o quantitativa de taninos em tr�s esp�cies de Stryphnodendron por cromatografia l�quida de alta efici�ncia . Brazilian journal of pharmaceutical sciences, 2009, vol. 45, no. 1, p. 135-143. DOI
Ardisson, L., Godoy, J. S., Ferreira, L. A. M., Stehmann, J. R., Brand�o, M. G. L. Prepara��o e caracteriza��o de extratos glic�licos enriquecidos em taninos a partir das cascas de Stryphnodendron adstringens (Mart.) Coville (Barbatim�o) . Revista brasileira de farmacognosia, 2002, vol. 12, no. 1, p. 27-34. DOI
Porto, Jorge Marcelo Padovani., Paiva, Renato., Campos, Nadia Alves., dos Reis, Michele Valquiria., de Souza, Ana Cristina., Santos, Paulo Augusto Almeida., Braga, Francyane Tavares. Cryopreservation of seeds of barbatimao with different water contents. Australian Journal of Basic and Applied Sciences, 2014, p. 250-256.
deMello, JP., Petereit, F., Nahrstedt, A. Prorobinetinidins from Stryphnodendron adstringens. PHYTOCHEMISTRY, 1996, vol. 42, no. 3, p. 857-862.
Lopes, Gisely Cristiny., Vieira Machado, Fatima Aparecida., Mendes de Toledo, Cleyton Eduardo., Sakuragui, Cassia Monica., Palazzo de Mello, Joao Carlos. Chemotaxonomic significance of 5-deoxyproanthocyanidins in Stryphnodendron species. BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2008, vol. 36, no. 12, p. 925-931. DOI
Vilar, Juliana Brandstetter., Prudente D'Oliveira, Maria Inez., Santos, Suzana da Costa., Chen, Lee Chen. Cytotoxic and genotixic investigation on barbatimao [Stryphnodendron adstringens (Mart.) Coville, 1910] extract. Brazilian Journal of Pharmaceutical Sciences, 2010, p. 687-694.
Souza, Paula Monteiro de., Sales, Paloma Michelle de., Simeoni, Luiz Alberto., Silva, Elton Clementino., Silveira, Damaris., Magalhaes, Perola de Oliveira. Inhibitory activity of alpha-amylase and alpha-glucosidase by plant extracts from the Brazilian cerrado. . Planta medica, 2012, vol. 78, no. 4, p. 393-9. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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