Botanical species · safety record
Styphnolobium japonicum
The EFSA Compendium of Botanicals holds 20 constituent measurements and 1 genotoxicity assay for Styphnolobium japonicum. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Styphnolobium japonicum (L.) Schott
Also recorded as
Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.
Regulatory presence
Health Canada's Licensed Natural Health Products Database holds 109 licensed products naming Styphnolobium japonicum as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.
Extract types on licence
Source material stated
What the records describe
Constituents measured
- Genistein4
- Isoflavones3
- Daidzein2
- Formononetin2
- Genistin2
- Sophoricoside2
- Biochanin-a1
- Coumestrol1
- Lignans1
- Matairesinol1
Plant parts
- Unspecified7
- Fruit peel5
- Fruit unspecified4
- Seed4
Preparations
- Solvent extraction20
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Genistein | Fruit unspecified | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Genistein | Seed | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Genistin | Fruit unspecified | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Genistin | Seed | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Isoflavones | Fruit unspecified | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Isoflavones | Seed | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Sophoricoside | Fruit unspecified | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Sophoricoside | Seed | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Biochanin-a | Unspecified | Solvent extraction | 830 Microgram/100 gram | GC-MS | No resolvable identifier |
| Coumestrol | Unspecified | Solvent extraction | 9.9 Microgram/100 gram | GC-MS | No resolvable identifier |
| Daidzein | Unspecified | Solvent extraction | 319 Microgram/100 gram | GC-MS | No resolvable identifier |
| Daidzein | Fruit peel | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | No resolvable identifier |
| Formononetin | Unspecified | Solvent extraction | 322 Microgram/100 gram | GC-MS | No resolvable identifier |
| Formononetin | Fruit peel | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | No resolvable identifier |
| Genistein | Unspecified | Solvent extraction | 265 Microgram/100 gram | GC-MS | No resolvable identifier |
| Genistein | Fruit peel | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | No resolvable identifier |
| Isoflavones | Fruit peel | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | No resolvable identifier |
| Lignans | Unspecified | Solvent extraction | 1590 Microgram/100 gram | GC-MS | No resolvable identifier |
| Matairesinol | Unspecified | Solvent extraction | 3.8 Microgram/100 gram | GC-MS | No resolvable identifier |
| Prunetin | Fruit peel | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | No resolvable identifier |
Genotoxicity testing
Outcomes of genotoxicity assays as recorded in the source. A negative assay is a result under those test conditions, not a clearance.
| Outcome | Endpoint | Test | Tested organism | Metabolic activation | Source |
|---|---|---|---|---|---|
| Positive | gene mutation | bacterial forward mutation assay | Salmonella typhimurium (as organism) | With and without | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- YIN, XJ., LIU, DX., WANG, HC., ZHOU, Y. A STUDY ON THE MUTAGENICITY OF 102 RAW PHARMACEUTICALS USED IN CHINESE TRADITIONAL MEDICINE. MUTATION RESEARCH, 1991, vol. 260, no. 1, p. 73-82.
- Mazur, Witold M., Duke, James A., Wahala, Kristiina., Rasku, Sirpa., Adlercreutz, Herman. Isoflavonoids and lignans in legumes: nutritional and health aspects in humans. Journal of nutritional biochemistry, 1998, vol. 9, no. 4, p. 193-200.
- Tang, Yuping., Lou, Fengchang., Wang, Jinghua. Isoflavonoids from the peel of Sophora japonica. Zhongcaoyao, 2002, vol. 33, no. 1, p. 20-21.
- Min, B., Oh, SR., Lee, HK., Takatsu, K., Chang, IM., Min, KR., Kim, Y. Sophoricoside analogs as the IL-5 inhibitors from Sophora japonica. Planta medica, 1999, vol. 65, no. 5, p. 408-412. DOI
- Abdallah, Hossam M., Al-Abd, Ahmed M., Asaad, Gihan F., Abdel-Naim, Ashraf B., El-halawany, Ali M. Isolation of antiosteoporotic compounds from seeds of Sophora japonica.. Plos one, 2014, vol. 9, no. 6, p. e98559. DOI
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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