Botanical species · safety record

Tanacetum parthenium

The EFSA Compendium of Botanicals holds 14 constituent measurements and 1 adverse-effect record for Tanacetum parthenium. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Tanacetum parthenium (L.) Sch.Bip.

14Constituent measurements

1Safety records

5Cited sources

223Licensed products (Canada)

Also recorded as

Chrysanthemum parthenium (L.) Bernh.

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 223 licensed products naming Tanacetum parthenium as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Dry
Extract Type TBA
Fresh

Source material stated

Aerial parts
Dried aerial part(s)
Dried aerial parts
Dried leaf
Feverfew leaf
Flower
Flowering aerial part(s)
Fresh or dried leaves

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Alkaloids	Aerial part of plants	Solvent extraction	—	Phytochemical screening	Resolve DOI
Camphor	Leaves	Essential oil	≤ 324.8 Milligram/gram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Camphor	Leaves	Essential oil	≥ 247.6 Milligram/gram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Camphor	Flower	Essential oil	≤ 187.6 Milligram/gram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Camphor	Flower	Essential oil	≥ 148.4 Milligram/gram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Camphor	Aerial part of plants	Essential oil	≤ 47.5 Percent	GC-MS	Resolve DOI
Camphor	Aerial part of plants	Essential oil	≥ 28 Percent	GC-MS	Resolve DOI
Costunolide	Leaves	Solvent extraction	—	LC-MS	Resolve DOI
Costunolide	Flower	Solvent extraction	—	LC-MS	Resolve DOI
Parthenolide	Leaves	Solvent extraction	—	LC-MS	Resolve DOI
Parthenolide	Flower	Solvent extraction	—	LC-MS	Resolve DOI
Saponins	Aerial part of plants	Solvent extraction	—	Phytochemical screening	Resolve DOI
Tannins	Aerial part of plants	Solvent extraction	—	Phytochemical screening	Resolve DOI
Parthenolide	Unspecified	Solvent extraction	—	Chromatographic tests	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Hepatotoxicity	Liver	Aerial part of plants	Solvent extraction	Rat (as animal)	Short-term toxicity	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Majdi, Mohammad., Charnikhova, Tatsiana., Bouwmeester, Harro. Genetical, developmental and spatial factors influencing parthenolide and its precursor costunolide in feverfew (Tanacetum parthenium L. Schulz Bip.) . Industrial crops and products, 2013, vol. 47, p. 270-276. DOI
Enciso-Roca, E., Aguilar-Felices, E.J., Tinco-Jayo, J.A., Arroyo-Acevedo, J.L., Herrera-Calderon, O., Aguilar-Carranza, C., Justil-Guerrero, H. Effects of acute and sub-acute oral toxicity studies of ethanol extract of Tanacetum parthenium (L) Sch. Bip. Aerial parts in mice and rats. Annual research and review in biology, 2017, vol. 19, no. 2. DOI
Salama, R., Sattayasai, J., Gande, A K., Sattayasai, N., Davis, M., Lattmann, E. Identification and evaluation of agents isolated from traditionally used herbs against Ophiophagus hannah venom. . Drug discoveries & therapeutics, 2012, vol. 6, no. 1, p. 18-23.
Vegh, Krisztina., Riethmuller, Eszter., Toth, Anita., Alberti, Agnes., Beni, Szabolcs., Balla, Jozsef., Kery, Agnes. Convergence chromatographic determination of camphor in the essential oil of Tanacetum parthenium L. . Biomedical chromatography, 2016, vol. 30, no. 12, p. 2031-2037. DOI
Hendriks, H., Bos, R., Woerdenbag, H. J. The essential oil of Tanacetum parthenium (L.) Schultz-Bip. Flavour and fragrance journal, 1996, vol. 11, no. 6, p. 367-371. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature