Botanical species · safety record
Tanacetum vulgare
The EFSA Compendium of Botanicals holds 46 constituent measurements and 1 adverse-effect record for Tanacetum vulgare. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Tanacetum vulgare L.
Regulatory presence
Health Canada's Licensed Natural Health Products Database holds 37 licensed products naming Tanacetum vulgare as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.
Source material stated
What the records describe
Constituents measured
- Alpha-thujone8
- 1,8-cineole6
- Artemisia ketone6
- Beta-thujone5
- (-)-camphor4
- Camphor3
- Iso-pinocamphone3
- Myrcene2
- Pinocarvone2
- Umbellulone2
Plant parts
- Aerial part of plants21
- Flower18
- Live plants6
- Leaves1
- Roots and other underground parts1
Preparations
- Essential oil26
- Solvent extraction21
Effect types
- Neurotoxicity1
Target tissues
- Neurologic1
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| (-)-camphor | Aerial part of plants | Essential oil | ≤ 39.2 Percent | GC-MS | Resolve DOI |
| (-)-camphor | Aerial part of plants | Essential oil | ≥ 0.5 Percent | GC-MS | Resolve DOI |
| 1,8-cineole | Flower | Solvent extraction | ≤ 47.12 Percent | GC-MS | Resolve DOI |
| 1,8-cineole | Aerial part of plants | Essential oil | ≥ 0.5 Percent | GC-MS | Resolve DOI |
| 1,8-cineole | Flower | Solvent extraction | ≥ 0.15 Percent | GC-MS | Resolve DOI |
| 1,8-cineole | Aerial part of plants | Essential oil | ≤ 51.4 Percent | GC-MS | Resolve DOI |
| Alpha-terthienyl | Aerial part of plants | Solvent extraction | 136 Microgram/gram | Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) | Resolve DOI |
| Alpha-thujone | Flower | Solvent extraction | ≤ 81.87 Percent | GC-MS | Resolve DOI |
| Alpha-thujone | Flower | Solvent extraction | ≥ 0.04 Percent | GC-MS | Resolve DOI |
| Alpha-thujone | Aerial part of plants | Essential oil | ≤ 73.5 Percent | GC-MS | Resolve DOI |
| Alpha-thujone | Aerial part of plants | Essential oil | ≥ 0.1 Percent | GC-MS | Resolve DOI |
| Artemisia ketone | Flower | Solvent extraction | ≤ 81.36 Percent | GC-MS | Resolve DOI |
| Artemisia ketone | Flower | Solvent extraction | ≥ 0.54 Percent | GC-MS | Resolve DOI |
| Artemisia ketone | Aerial part of plants | Essential oil | ≤ 71.5 Percent | GC-MS | Resolve DOI |
| Artemisia ketone | Aerial part of plants | Essential oil | ≥ 19.8 Percent | GC-MS | Resolve DOI |
| Beta-thujone | Aerial part of plants | Essential oil | ≤ 95.7 Percent | GC-MS | Resolve DOI |
| Beta-thujone | Aerial part of plants | Essential oil | ≥ 5 Percent | GC-MS | Resolve DOI |
| Camphor | Flower | Solvent extraction | ≤ 73.02 Percent | GC-MS | Resolve DOI |
| Camphor | Flower | Solvent extraction | ≥ 0.06 Percent | GC-MS | Resolve DOI |
| Iso-pinocamphone | Flower | Solvent extraction | ≥ 0.03 Percent | GC-MS | Resolve DOI |
| Iso-pinocamphone | Flower | Solvent extraction | ≤ 19.1 Percent | GC-MS | Resolve DOI |
| Myrcene | Flower | Solvent extraction | ≤ 39.39 Percent | GC-MS | Resolve DOI |
| Myrcene | Flower | Solvent extraction | ≥ 1.13 Percent | GC-MS | Resolve DOI |
| Pinocarvone | Flower | Solvent extraction | ≤ 4.38 Percent | GC-MS | Resolve DOI |
| Pinocarvone | Flower | Solvent extraction | ≥ 1.06 Percent | GC-MS | Resolve DOI |
| Umbellulone | Flower | Solvent extraction | ≤ 12.18 Percent | GC-MS | Resolve DOI |
| Umbellulone | Flower | Solvent extraction | ≥ 0.03 Percent | GC-MS | Resolve DOI |
| Verbenone | Flower | Solvent extraction | ≥ 0.21 Percent | GC-MS | Resolve DOI |
| Verbenone | Flower | Solvent extraction | ≤ 3.49 Percent | GC-MS | Resolve DOI |
| (-)-camphor | Live plants | Essential oil | ≤ 1.1 Percent | GC-FID | No resolvable identifier |
| (-)-camphor | Live plants | Essential oil | ≥ 1 Percent | GC-FID | No resolvable identifier |
| 1,8-cineole | Aerial part of plants | Essential oil | ≤ 32.7 Percent | GC-MS | No resolvable identifier |
| 1,8-cineole | Aerial part of plants | Essential oil | ≥ 7 Percent | GC-MS | No resolvable identifier |
| Alpha-thujone | Live plants | Essential oil | ≤ 1.6 Percent | GC-FID | No resolvable identifier |
| Alpha-thujone | Live plants | Essential oil | ≥ 0.4 Percent | GC-FID | No resolvable identifier |
| Alpha-thujone | Aerial part of plants | Essential oil | ≤ 71.5 Percent | GC-MS | No resolvable identifier |
| Alpha-thujone | Aerial part of plants | Essential oil | ≥ 0.8 Percent | GC-MS | No resolvable identifier |
| Artemisia ketone | Aerial part of plants | Essential oil | ≤ 30.5 Percent | GC-MS | No resolvable identifier |
| Artemisia ketone | Aerial part of plants | Essential oil | ≥ 13.1 Percent | GC-MS | No resolvable identifier |
| Beta-thujone | Live plants | Essential oil | ≤ 92.2 Percent | GC-FID | No resolvable identifier |
40 of 46 records are shown, ordered so that records carrying a resolvable reference come first.
Recorded adverse effects
Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.
| Effect | Target tissue | Plant part | Preparation | Test organism | Test type | Source |
|---|---|---|---|---|---|---|
| Neurotoxicity | Neurologic | Leaves | Solvent extraction | House mouse (as animal) | Acute toxicity | Resolve DOI |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Keskitalo, M., Pehu, E., Simon, JE. Variation in volatile compounds from tansy (Tanacetum vulgare L.) related to genetic and morphological differences of genotypes . Biochemical systematics and ecology, 2001, vol. 29, no. 3, p. 267-285. DOI
- Rohloff, J., Mordal, R., Dragland, S. Chemotypical variation of tansy (Tanacetum vulgare L.) from 40 different locations in Norway . Journal of agricultural and food chemistry, 2004, vol. 52, no. 6, p. 1742-1748. DOI
- Mockute, D., Judzentiene, A. Composition of the essential oils of Tanacetum vulgare L. growing wild in Vilnius district (Lithuania) . Journal of essential oil research, 2004, vol. 16, no. 6, p. 550-553.
- Chiasson, H., Belanger, A., Bostanian, N., Vincent, C., Poliquin, A. Acaricidal properties of Artemisia absinthium and Tanacetum vulgare (Asteraceae) essential oils obtained by three methods of extraction . Journal of economic entomology, 2001, vol. 94, no. 1, p. 167-171.
- Wishart, DS., Jewison, T., Guo, AC., Wilson, M., Knox, C., Liu, Y., Djoumbou, Y., Mandal, R., Aziat, F., Dong, E., Bouatra, S., Sinelnikov, I., Arndt, D., Xia, J., Liu, P., Yallou, F., Bjorndahl, T., Perez-Pineiro, R., Eisner, R., Allen, F., Neveu, V., Greiner, R., Scalbert, A. 1-Acetoxy-4,6-tetradecadiene-8,10,12-triyne (HMDB30881). Human metabolome database, 2012.
- TOSI, B., BONORA, A., DALLOLIO, G., BRUNI, A. SCREENING FOR TOXIC THIOPHENE COMPOUNDS FROM CRUDE DRUGS OF THE FAMILY COMPOSITAE USED IN NORTHERN ITALY . Phytotherapy research, 1991, vol. 5, no. 2, p. 59-62. DOI
- Lahlou, Sanaa., Israili, Zafar H., Lyoussi, Badiaa. Acute and chronic toxicity of a lyophilised aqueous extract of Tanacetum vulgare leaves in rodents . Journal of ethnopharmacology, 2008, vol. 117, no. 2, p. 221-227. DOI
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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