Botanical species · safety record

Tanacetum vulgare

The EFSA Compendium of Botanicals holds 46 constituent measurements and 1 adverse-effect record for Tanacetum vulgare. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Tanacetum vulgare L.

46Constituent measurements
1Safety records
7Cited sources
37Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 37 licensed products naming Tanacetum vulgare as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Source material stated

  • Aerial parts
  • Fresh aerial parts collected at flowering time minus stems
  • Herb top
  • Leaf

What the records describe

Constituents measured

  • Alpha-thujone8
  • 1,8-cineole6
  • Artemisia ketone6
  • Beta-thujone5
  • (-)-camphor4
  • Camphor3
  • Iso-pinocamphone3
  • Myrcene2
  • Pinocarvone2
  • Umbellulone2

Plant parts

  • Aerial part of plants21
  • Flower18
  • Live plants6
  • Leaves1
  • Roots and other underground parts1

Preparations

  • Essential oil26
  • Solvent extraction21

Effect types

  • Neurotoxicity1

Target tissues

  • Neurologic1

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
(-)-camphorAerial part of plantsEssential oil≤ 39.2 PercentGC-MSResolve DOI
(-)-camphorAerial part of plantsEssential oil≥ 0.5 PercentGC-MSResolve DOI
1,8-cineoleFlowerSolvent extraction≤ 47.12 PercentGC-MSResolve DOI
1,8-cineoleAerial part of plantsEssential oil≥ 0.5 PercentGC-MSResolve DOI
1,8-cineoleFlowerSolvent extraction≥ 0.15 PercentGC-MSResolve DOI
1,8-cineoleAerial part of plantsEssential oil≤ 51.4 PercentGC-MSResolve DOI
Alpha-terthienylAerial part of plantsSolvent extraction136 Microgram/gramGelpermeation, High Performance Thin Layer Chromatography (HPTLC)Resolve DOI
Alpha-thujoneFlowerSolvent extraction≤ 81.87 PercentGC-MSResolve DOI
Alpha-thujoneFlowerSolvent extraction≥ 0.04 PercentGC-MSResolve DOI
Alpha-thujoneAerial part of plantsEssential oil≤ 73.5 PercentGC-MSResolve DOI
Alpha-thujoneAerial part of plantsEssential oil≥ 0.1 PercentGC-MSResolve DOI
Artemisia ketoneFlowerSolvent extraction≤ 81.36 PercentGC-MSResolve DOI
Artemisia ketoneFlowerSolvent extraction≥ 0.54 PercentGC-MSResolve DOI
Artemisia ketoneAerial part of plantsEssential oil≤ 71.5 PercentGC-MSResolve DOI
Artemisia ketoneAerial part of plantsEssential oil≥ 19.8 PercentGC-MSResolve DOI
Beta-thujoneAerial part of plantsEssential oil≤ 95.7 PercentGC-MSResolve DOI
Beta-thujoneAerial part of plantsEssential oil≥ 5 PercentGC-MSResolve DOI
CamphorFlowerSolvent extraction≤ 73.02 PercentGC-MSResolve DOI
CamphorFlowerSolvent extraction≥ 0.06 PercentGC-MSResolve DOI
Iso-pinocamphoneFlowerSolvent extraction≥ 0.03 PercentGC-MSResolve DOI
Iso-pinocamphoneFlowerSolvent extraction≤ 19.1 PercentGC-MSResolve DOI
MyrceneFlowerSolvent extraction≤ 39.39 PercentGC-MSResolve DOI
MyrceneFlowerSolvent extraction≥ 1.13 PercentGC-MSResolve DOI
PinocarvoneFlowerSolvent extraction≤ 4.38 PercentGC-MSResolve DOI
PinocarvoneFlowerSolvent extraction≥ 1.06 PercentGC-MSResolve DOI
UmbelluloneFlowerSolvent extraction≤ 12.18 PercentGC-MSResolve DOI
UmbelluloneFlowerSolvent extraction≥ 0.03 PercentGC-MSResolve DOI
VerbenoneFlowerSolvent extraction≥ 0.21 PercentGC-MSResolve DOI
VerbenoneFlowerSolvent extraction≤ 3.49 PercentGC-MSResolve DOI
(-)-camphorLive plantsEssential oil≤ 1.1 PercentGC-FIDNo resolvable identifier
(-)-camphorLive plantsEssential oil≥ 1 PercentGC-FIDNo resolvable identifier
1,8-cineoleAerial part of plantsEssential oil≤ 32.7 PercentGC-MSNo resolvable identifier
1,8-cineoleAerial part of plantsEssential oil≥ 7 PercentGC-MSNo resolvable identifier
Alpha-thujoneLive plantsEssential oil≤ 1.6 PercentGC-FIDNo resolvable identifier
Alpha-thujoneLive plantsEssential oil≥ 0.4 PercentGC-FIDNo resolvable identifier
Alpha-thujoneAerial part of plantsEssential oil≤ 71.5 PercentGC-MSNo resolvable identifier
Alpha-thujoneAerial part of plantsEssential oil≥ 0.8 PercentGC-MSNo resolvable identifier
Artemisia ketoneAerial part of plantsEssential oil≤ 30.5 PercentGC-MSNo resolvable identifier
Artemisia ketoneAerial part of plantsEssential oil≥ 13.1 PercentGC-MSNo resolvable identifier
Beta-thujoneLive plantsEssential oil≤ 92.2 PercentGC-FIDNo resolvable identifier

40 of 46 records are shown, ordered so that records carrying a resolvable reference come first.

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

EffectTarget tissuePlant partPreparationTest organismTest typeSource
NeurotoxicityNeurologicLeavesSolvent extractionHouse mouse (as animal)Acute toxicityResolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Keskitalo, M., Pehu, E., Simon, JE. Variation in volatile compounds from tansy (Tanacetum vulgare L.) related to genetic and morphological differences of genotypes . Biochemical systematics and ecology, 2001, vol. 29, no. 3, p. 267-285. DOI
  2. Rohloff, J., Mordal, R., Dragland, S. Chemotypical variation of tansy (Tanacetum vulgare L.) from 40 different locations in Norway . Journal of agricultural and food chemistry, 2004, vol. 52, no. 6, p. 1742-1748. DOI
  3. Mockute, D., Judzentiene, A. Composition of the essential oils of Tanacetum vulgare L. growing wild in Vilnius district (Lithuania) . Journal of essential oil research, 2004, vol. 16, no. 6, p. 550-553.
  4. Chiasson, H., Belanger, A., Bostanian, N., Vincent, C., Poliquin, A. Acaricidal properties of Artemisia absinthium and Tanacetum vulgare (Asteraceae) essential oils obtained by three methods of extraction . Journal of economic entomology, 2001, vol. 94, no. 1, p. 167-171.
  5. Wishart, DS., Jewison, T., Guo, AC., Wilson, M., Knox, C., Liu, Y., Djoumbou, Y., Mandal, R., Aziat, F., Dong, E., Bouatra, S., Sinelnikov, I., Arndt, D., Xia, J., Liu, P., Yallou, F., Bjorndahl, T., Perez-Pineiro, R., Eisner, R., Allen, F., Neveu, V., Greiner, R., Scalbert, A. 1-Acetoxy-4,6-tetradecadiene-8,10,12-triyne (HMDB30881). Human metabolome database, 2012.
  6. TOSI, B., BONORA, A., DALLOLIO, G., BRUNI, A. SCREENING FOR TOXIC THIOPHENE COMPOUNDS FROM CRUDE DRUGS OF THE FAMILY COMPOSITAE USED IN NORTHERN ITALY . Phytotherapy research, 1991, vol. 5, no. 2, p. 59-62. DOI
  7. Lahlou, Sanaa., Israili, Zafar H., Lyoussi, Badiaa. Acute and chronic toxicity of a lyophilised aqueous extract of Tanacetum vulgare leaves in rodents . Journal of ethnopharmacology, 2008, vol. 117, no. 2, p. 221-227. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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