Botanical species · safety record

Terminalia chebula

The EFSA Compendium of Botanicals holds 4 constituent measurements and 2 adverse-effect records for Terminalia chebula. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Terminalia chebula Retz.

4Constituent measurements
2Safety records
4Cited sources
364Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 364 licensed products naming Terminalia chebula as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

  • Dry
  • Fresh
  • fluid

Source material stated

  • Dried fruit
  • Dried ripe fruit
  • Dried young fruit
  • Fruit
  • Fruit extract
  • Fruit flesh
  • Fruit mesocarp
  • Fruit peel

What the records describe

Constituents measured

  • Tannins2
  • Alkaloids1
  • Gallic acid1

Plant parts

  • Fruit unspecified3
  • Leaves3

Preparations

  • Solvent extraction6

Effect types

  • Digestive2

Target tissues

  • Digestive: pancreas2

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
Gallic acidFruit unspecifiedSolvent extractionHPLC with standard detection methodsResolve DOI
TanninsFruit unspecifiedSolvent extractionStandard Chromatographic tests (paper- thin layer- and column chromatography)Resolve DOI
AlkaloidsLeavesSolvent extractionPhytochemical screeningNo resolvable identifier
TanninsLeavesSolvent extractionPhytochemical screeningNo resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

EffectTarget tissuePlant partPreparationTest organismTest typeSource
DigestiveDigestive: pancreasFruit unspecifiedSolvent extractionIn vitroResolve DOI
DigestiveDigestive: pancreasLeavesSolvent extractionIn vitroNo resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Anam, K., Widharna, R. M., Kusrini, D. alpha-Glucosidase Inhibitor Activity of Terminalia Species. International journal of pharmacology, 2009, vol. 5, no. 4, p. 277-280.
  2. Gao, Hong., Huang, Yi-Na., Xu, Pei-Yu., Kawabata, Jun. Inhibitory effect on alpha-glucosidase by the fruits of Terminalia chebula Retz. . Food chemistry, 2007, vol. 105, no. 2, p. 628-634. DOI
  3. Kaur, S., Grover, IS., Singh, M., Kaur, S. Antimutagenicity of hydrolyzable tannins from Terminalia chebula in Salmonella typhimurium . Mutation research-genetic toxicology and environmental mutagenesis, 1998, vol. 419, no. 1-3, p. 169-179. DOI
  4. LEE, SH., RYU, SY., CHOI, SU., LEE, CO., NO, ZS., KIM, SK., AHN, JW. HYDROLYZABLE TANNINS AND RELATED COMPOUND HAVING CYTOTOXIC ACTIVITY FROM THE FRUITS OF TERMINALIA-CHEBULA . Archives of pharmacal research, 1995, vol. 18, no. 2, p. 118-120. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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