Botanical species · safety record
Teucrium polium
The EFSA Compendium of Botanicals holds 10 constituent measurements and 6 adverse-effect records for Teucrium polium. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Teucrium polium L.
Regulatory presence
No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.
What the records describe
Constituents measured
- Carvone2
- Menthone2
- Myrcene2
- Clerodane-type diterpenes1
- Podophyllotoxin1
- Saponins1
- Verbenone1
Plant parts
- Aerial part of plants16
Preparations
- Solvent extraction13
- Drying (dehydration)2
- Essential oil1
Effect types
- Hepatotoxicity3
- Systemic2
- Digestive1
Target tissues
- Liver5
- Lung1
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Myrcene | Aerial part of plants | Solvent extraction | ≥ 5 Percent | GC-MS | Resolve DOI |
| Myrcene | Aerial part of plants | Solvent extraction | ≤ 11.5 Percent | GC-MS | Resolve DOI |
| Saponins | Aerial part of plants | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Carvone | Aerial part of plants | Solvent extraction | ≤ 1.35 Percent | GC-MS | No resolvable identifier |
| Carvone | Aerial part of plants | Solvent extraction | ≥ 0.88 Percent | GC-MS | No resolvable identifier |
| Clerodane-type diterpenes | Aerial part of plants | Solvent extraction | — | Unspecified | No resolvable identifier |
| Menthone | Aerial part of plants | Solvent extraction | ≤ 2.65 Percent | GC-MS | No resolvable identifier |
| Menthone | Aerial part of plants | Solvent extraction | ≥ 0.56 Percent | GC-MS | No resolvable identifier |
| Podophyllotoxin | Aerial part of plants | Solvent extraction | 0.09 Percent | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | No resolvable identifier |
| Verbenone | Aerial part of plants | Essential oil | 4 Percent | GC-MS | No resolvable identifier |
Recorded adverse effects
Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.
| Effect | Target tissue | Plant part | Preparation | Test organism | Test type | Source |
|---|---|---|---|---|---|---|
| Hepatotoxicity | Liver | Aerial part of plants | Solvent extraction | Human (as organism) | Case report | Resolve DOI |
| Digestive | Liver | Aerial part of plants | Solvent extraction | Human (as organism) | Case report | No resolvable identifier |
| Hepatotoxicity | Liver | Aerial part of plants | Solvent extraction | House mouse (as animal) | Short-term toxicity | No resolvable identifier |
| Hepatotoxicity | Liver | Aerial part of plants | Solvent extraction | House mouse (as animal) | Acute toxicity | No resolvable identifier |
| Systemic | Liver | Aerial part of plants | Drying (dehydration) | Rat (as animal) | Subchronic | No resolvable identifier |
| Systemic | Lung | Aerial part of plants | Drying (dehydration) | Rat (as animal) | Subchronic | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Abu Sitta, K.H., Shomah, M.S., Salhab, A.S. Hepatotoxicity of teucrium polium L tea: Supporting evidence in mice models. Australian journal of medical herbalism, 2009, vol. 21, no. 4, p. 106-109.
- Starakis, Ioannis., Siagris, Dimitrios., Leonidou, Lydia., Mazokopakis, Elias., Tsamandas, Athanasios., Karatza, Chrysoula. Hepatitis caused by the herbal remedy Teucrium polium L.. European journal of gastroenterology & hepatology, 2006, vol. 18, no. 6, p. 681-683. DOI
- Soylu, A.R., Sivri, B., Bayraktar, Y. Hepatoxicity of Teucrium polium. Turkish journal of gastroenterology, 1998, vol. 9, no. 2, p. 196-197.
- Bachtarzi, K., Hilmi, S., Laouar, H., Belkheiri, A., Pacha, Y.H. The chronic toxic effect of Teucrium polium aqueous extract on some blood parameters in rat. Der pharma chemica, 2016, vol. 8, no. 19, p. 384-387.
- Chizzola, R. Volatile compounds from some wild growing aromatic herbs of the Lamiaceae from southern France. PLANT BIOSYSTEMS, 2006, vol. 140, no. 2, p. 206-210. DOI
- Scognamiglio, Monica., D'Abrosca, Brigida., Pacifico, Severina., Isidori, Marina., Esposito, Assunta., Fiorentino, Antonio., Patil, BS., Jayaprakasha, GK., Murthy, KNC., Seeram, NP. Mediterranean Wild Plants As Useful Sources of Potential Natural Food Additives . Emerging trends in dietary components for preventing and combating disease, 2012, vol. 1093, p. 209-235.
- Afifi, F.U., Abu-Irmaileh, B.E., Al-Noubani, R.A. Comparative analysis of the essential oils of Teucrium polium L. grown in different arid & semi arid habitats in Jordan. Jordan journal of pharmaceutical sciences, 2009, vol. 2, no. 1, p. 42-52.
- Elmasri, Wael A., Hegazy, Mohamed-Elamir F., Mechref, Yehia., Pare, Paul W. Cytotoxic saponin poliusaposide from Teucrium polium. Rsc advances, 2015, vol. 5, no. 34, p. 27126-27133. DOI
- Konuklugil, Belma. Investigation of podophyllotoxin in some plants in Lamiaceae using HPLC. Ankara universitesi eczacilik fakultesi dergisi, 1996, vol. 25, no. 1, p. 23-27.
- De Martino, Laura., Formisano, Carmen., Mancini, Emilia., De Feo, Vincenzo., Piozzi, Franco., Rigano, Daniela., Senatore, Felice. Chemical Composition and Phytotoxic Effects of Essential Oils from Four Teucrium Species . Natural product communications, 2010, vol. 5, no. 12, p. 1969-1976.
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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