Botanical species · safety record

Teucrium polium

The EFSA Compendium of Botanicals holds 10 constituent measurements and 6 adverse-effect records for Teucrium polium. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Teucrium polium L.

10Constituent measurements
6Safety records
10Cited sources
0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

  • Carvone2
  • Menthone2
  • Myrcene2
  • Clerodane-type diterpenes1
  • Podophyllotoxin1
  • Saponins1
  • Verbenone1

Plant parts

  • Aerial part of plants16

Preparations

  • Solvent extraction13
  • Drying (dehydration)2
  • Essential oil1

Effect types

  • Hepatotoxicity3
  • Systemic2
  • Digestive1

Target tissues

  • Liver5
  • Lung1

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
MyrceneAerial part of plantsSolvent extraction≥ 5 PercentGC-MSResolve DOI
MyrceneAerial part of plantsSolvent extraction≤ 11.5 PercentGC-MSResolve DOI
SaponinsAerial part of plantsSolvent extractionNuclear Magnetic Resonance (NMR)Resolve DOI
CarvoneAerial part of plantsSolvent extraction≤ 1.35 PercentGC-MSNo resolvable identifier
CarvoneAerial part of plantsSolvent extraction≥ 0.88 PercentGC-MSNo resolvable identifier
Clerodane-type diterpenesAerial part of plantsSolvent extractionUnspecifiedNo resolvable identifier
MenthoneAerial part of plantsSolvent extraction≤ 2.65 PercentGC-MSNo resolvable identifier
MenthoneAerial part of plantsSolvent extraction≥ 0.56 PercentGC-MSNo resolvable identifier
PodophyllotoxinAerial part of plantsSolvent extraction0.09 PercentHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)No resolvable identifier
VerbenoneAerial part of plantsEssential oil4 PercentGC-MSNo resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

EffectTarget tissuePlant partPreparationTest organismTest typeSource
HepatotoxicityLiverAerial part of plantsSolvent extractionHuman (as organism)Case reportResolve DOI
DigestiveLiverAerial part of plantsSolvent extractionHuman (as organism)Case reportNo resolvable identifier
HepatotoxicityLiverAerial part of plantsSolvent extractionHouse mouse (as animal)Short-term toxicityNo resolvable identifier
HepatotoxicityLiverAerial part of plantsSolvent extractionHouse mouse (as animal)Acute toxicityNo resolvable identifier
SystemicLiverAerial part of plantsDrying (dehydration)Rat (as animal)SubchronicNo resolvable identifier
SystemicLungAerial part of plantsDrying (dehydration)Rat (as animal)SubchronicNo resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Abu Sitta, K.H., Shomah, M.S., Salhab, A.S. Hepatotoxicity of teucrium polium L tea: Supporting evidence in mice models. Australian journal of medical herbalism, 2009, vol. 21, no. 4, p. 106-109.
  2. Starakis, Ioannis., Siagris, Dimitrios., Leonidou, Lydia., Mazokopakis, Elias., Tsamandas, Athanasios., Karatza, Chrysoula. Hepatitis caused by the herbal remedy Teucrium polium L.. European journal of gastroenterology & hepatology, 2006, vol. 18, no. 6, p. 681-683. DOI
  3. Soylu, A.R., Sivri, B., Bayraktar, Y. Hepatoxicity of Teucrium polium. Turkish journal of gastroenterology, 1998, vol. 9, no. 2, p. 196-197.
  4. Bachtarzi, K., Hilmi, S., Laouar, H., Belkheiri, A., Pacha, Y.H. The chronic toxic effect of Teucrium polium aqueous extract on some blood parameters in rat. Der pharma chemica, 2016, vol. 8, no. 19, p. 384-387.
  5. Chizzola, R. Volatile compounds from some wild growing aromatic herbs of the Lamiaceae from southern France. PLANT BIOSYSTEMS, 2006, vol. 140, no. 2, p. 206-210. DOI
  6. Scognamiglio, Monica., D'Abrosca, Brigida., Pacifico, Severina., Isidori, Marina., Esposito, Assunta., Fiorentino, Antonio., Patil, BS., Jayaprakasha, GK., Murthy, KNC., Seeram, NP. Mediterranean Wild Plants As Useful Sources of Potential Natural Food Additives . Emerging trends in dietary components for preventing and combating disease, 2012, vol. 1093, p. 209-235.
  7. Afifi, F.U., Abu-Irmaileh, B.E., Al-Noubani, R.A. Comparative analysis of the essential oils of Teucrium polium L. grown in different arid & semi arid habitats in Jordan. Jordan journal of pharmaceutical sciences, 2009, vol. 2, no. 1, p. 42-52.
  8. Elmasri, Wael A., Hegazy, Mohamed-Elamir F., Mechref, Yehia., Pare, Paul W. Cytotoxic saponin poliusaposide from Teucrium polium. Rsc advances, 2015, vol. 5, no. 34, p. 27126-27133. DOI
  9. Konuklugil, Belma. Investigation of podophyllotoxin in some plants in Lamiaceae using HPLC. Ankara universitesi eczacilik fakultesi dergisi, 1996, vol. 25, no. 1, p. 23-27.
  10. De Martino, Laura., Formisano, Carmen., Mancini, Emilia., De Feo, Vincenzo., Piozzi, Franco., Rigano, Daniela., Senatore, Felice. Chemical Composition and Phytotoxic Effects of Essential Oils from Four Teucrium Species . Natural product communications, 2010, vol. 5, no. 12, p. 1969-1976.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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