Botanical species · safety record

Thapsia garganica

The EFSA Compendium of Botanicals holds 11 constituent measurements for Thapsia garganica. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Thapsia garganica L.

11Constituent measurements

0Safety records

6Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Guaianolides	Fruit unspecified	Solvent extraction	—	HPLC-UV	Resolve DOI
Myrcene	Roots and other underground parts	Essential oil	2.88 Percent	GC-MS	Resolve DOI
Phenylpropanoids	Fruit unspecified	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Thapsigargin	Roots and other underground parts	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Thapsigargin	Fruit unspecified	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Thapsigargin	Unspecified	Solvent extraction	—	Unspecified	Resolve DOI
Benzyl salicylate	Bark	Essential oil	5.18 Percent	GC-MS	No resolvable identifier
Beta-thujone	Bark	Essential oil	14.86 Percent	GC-MS	No resolvable identifier
Elemicin	Bark	Essential oil	13.06 Percent	GC-MS	No resolvable identifier
Myrcene	Bark	Essential oil	1.45 Percent	GC-MS	No resolvable identifier
Myristicin	Bark	Essential oil	15.07 Percent	GC-MS	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Ollivier, Anthony., Grougnet, Raphael., Cachet, Xavier., Meriane, Djamila., Ardisson, Janick., Boutefnouchet, Sabrina., Deguin, Brigitte. Large scale purification of the SERCA inhibitor Thapsigargin from Thapsia garganica L. roots using centrifugal partition chromatography . Journal of chromatography b-analytical technologies in the biomedical and life sciences, 2013, vol. 926, p. 16-20. DOI
JAGER, AK., GUDIKSEN, L., ADSERSEN, A., SMITT, UW. HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY OF THAPSIGARGINS. Journal of chromatography, 1993, vol. 634, no. 1, p. 135-137. DOI
Hachem, Kadda., Mebarki, Moubarek., Hartani, Abdelkrim., Benabdesslem, Yasmina., Kaid-Harche, Meriem. Essential Oil Composition of the Root Bark of Thapsia garganica (L.) Growing in Northwestern Algeria . Journal of essential oil bearing plants, 2017, vol. 20, no. 3, p. 860-863.
Drew, Damian Paul., Rasmussen, Soren K., Avato, Pinarosa., Simonsen, Henrik Toft. A Comparison of Headspace Solid-phase Microextraction and Classic Hydrodistillation for the Identification of Volatile Constituents from Thapsia spp. Provides Insights into Guaianolide Biosynthesis in Apiaceae . Phytochemical analysis, 2012, vol. 23, no. 1, p. 44-51. DOI
Liu, Huizhen., Jensen, Kent Gunnertoft., Tran, Linh My., Chen, Ming., Zhai, Lin., Olsen, Carl Erik., Sohoel, Helmer., Denmeade, Samuel R., Isaacs, John T., Christensen, S. Brogger. Cytotoxic phenylpropanoids and an additional thapsigargin analogue isolated from Thapsia garganica . Phytochemistry, 2006, vol. 67, no. 24, p. 2651-2658. DOI
Nhu Thi Quynh Doan., Paulsen, Eleonora Sandholdt., Sehgal, Pankaj., Moller, Jesper Vuust., Nissen, Poul., Denmeade, Samuel R., Isaacs, John T., Dionne, Craig A., Christensen, Soren Brogger. Targeting thapsigargin towards tumors. Steroids, 2015, vol. 97, p. 2-7. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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