Botanical species · safety record

Toddalia asiatica

The EFSA Compendium of Botanicals holds 29 constituent measurements and 1 adverse-effect record for Toddalia asiatica. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Toddalia asiatica (L.) Lam.

29Constituent measurements

1Safety records

12Cited sources

0Licensed products (Canada)

Also recorded as

Paullinia asiatica L.

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Alkaloids	Wood	Solvent extraction	—	—	Resolve DOI
Alkaloids	Roots and other underground parts	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	Resolve DOI
Coumarins	Wood	Solvent extraction	—	—	Resolve DOI
Coumarins	Roots and other underground parts	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	Resolve DOI
Coumarins	Aerial part of plants	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	Resolve DOI
Isopimpinellin	Roots and other underground parts	Solvent extraction	3.9 Milligram/millilitre	LC-MS	Resolve DOI
Isopimpinellin	Roots and other underground parts	Solvent extraction	0.85 Milligram/gram	UHPLC-MS-MS	Resolve DOI
Phellopterin	Roots and other underground parts	Solvent extraction	5 Milligram/millilitre	LC-MS	Resolve DOI
Phellopterin	Roots and other underground parts	Solvent extraction	0.95 Milligram/gram	UHPLC-MS-MS	Resolve DOI
Pimpinellin	Roots and other underground parts	Solvent extraction	2.55 Milligram/gram	UHPLC-MS-MS	Resolve DOI
Pimpinellin	Roots and other underground parts	Solvent extraction	10.1 Milligram/millilitre	LC-MS	Resolve DOI
Alkaloids	Live plants	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Alkaloids	Roots and other underground parts	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	No resolvable identifier
Alkaloids	Roots and other underground parts	—	—	Traditional analytical techniques (wet chemical tests)	No resolvable identifier
Alkaloids	Leaves	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Chelerythrine	Bark	—	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Chelerythrine	Stem / stalk	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	No resolvable identifier
Coumarins	Leaves	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Coumarins	Roots and other underground parts	—	—	Traditional analytical techniques (wet chemical tests)	No resolvable identifier
Coumarins	Stem / stalk	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	No resolvable identifier
Coumarins	Roots and other underground parts	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	No resolvable identifier
Oxalates	Fruit unspecified	Solvent extraction	≥ 0.5 Milligram/gram	Traditional analytical techniques (wet chemical tests)	No resolvable identifier
Oxalates	Fruit unspecified	Solvent extraction	≤ 4.7 Milligram/gram	Traditional analytical techniques (wet chemical tests)	No resolvable identifier
Phytic acid	Fruit unspecified	Solvent extraction	≤ 9.8 Milligram/gram	Traditional analytical techniques (wet chemical tests)	No resolvable identifier
Phytic acid	Fruit unspecified	Solvent extraction	≥ 9.2 Milligram/gram	Traditional analytical techniques (wet chemical tests)	No resolvable identifier
Saponins	Fruit unspecified	Solvent extraction	140 Milligram/gram	Traditional analytical techniques (wet chemical tests)	No resolvable identifier
Tannins	Live plants	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Tannins	Leaves	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Tannins	Fruit unspecified	Solvent extraction	64 Milligram/gram	Traditional analytical techniques (wet chemical tests)	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Other toxicities	—	Live plants	Solvent extraction	Rat (as animal)	Acute toxicity	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Tsai, IL., Wun, MF., Teng, CM., Ishikawa, T., Chen, IS. Anti-platelet aggregation constituents from formosan Toddalia asiatica. Phytochemistry, 1998, vol. 48, no. 8, p. 1377-1382. DOI
Suresh B., Dhanasekaran S., Elango K., Sethuraman M., Rajan S. Anti-pyretic activity of some plants in female albino rats: a preliminary report. Ancient science of life, 1995, p. 253-257.
Tsai, IL., Fang, SC., Ishikawa, T., Chang, CT., Chen, IS. N-cyclohexyl amides and a dimeric coumarin from formosan Toddalia asiatica. PHYTOCHEMISTRY, 1997, vol. 44, no. 7, p. 1383-1386.
CHEN, IS., TSAI, IL., WU, SJ., SHEEN, WS., ISHIKAWA, T., ISHII, H. TODDAQUINOLINE FROM FORMOSAN TODDALIA-ASIATICA. PHYTOCHEMISTRY, 1993, vol. 34, no. 5, p. 1449-1451. DOI
Tsai, I.-L., Chang, R.-G., Fang, S.-C., Ishikawa, T., Chen, I.-S. Chemical constituents from the root bark of Formosan Toddalia asiatica. Chinese pharmaceutical journal, 1996, vol. 48, no. 1, p. 63-75.
Yang, Liang., Guo, Jing., Fan, Baocheng. Fingerprint chromatography of cortex toddalia by HPLC. Zhongguo yaoye, 2011, p. 21-22.
Chen, Xiaoxue., Reheman, Simayi., Long, Shengjing. Studies on chemical constituents of Toddalia asiatica stems. Xibei yaoxue zazhi, 2013, p. 337-339.
Patil, Arun V., Jadhav, Varsha D., Patil, Poonam C. Ethnomedicinal and pharmacognostical studies on leaves of Toddalia asiatica L. Pharmacia Sinica, 2013, p. 76-80.
Wang, F., Xu, Y., Liu, JK. New geranyloxycoumarins from Toddalia asiatica. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2009, vol. 11, no. 8, p. 752-756. DOI
Liu, Zhigang., Jiang, Minyan., Lu, Xiumei., Qin, Feng., Song, Yang., Wen, Jing., Li, Famei. Simultaneous determination of pimpinellin, isopimpinellin and phellopterin in rat plasma by a validated UPLC-MS/MS and its application to a pharmacokinetic study after administration of Toddalia asiatica extract . Journal of chromatography b-analytical technologies in the biomedical and life sciences, 2012, vol. 891, p. 102-108. DOI
Qiu, HY., Xiao, XH., Li, GK. Separation and purification of furanocoumarins from Toddalia asiatica (L.) Lam. using microwave-assisted extraction coupled with high-speed counter-current chromatography. JOURNAL OF SEPARATION SCIENCE, 2012, vol. 35, no. 7, p. 901-906. DOI
Rout, Pramodini., Basak, Uday Chand. Evaluation of antinutritional factors in sixteen wild edible fruits of Odisha, India. International Journal of Current Science, 2014, p. 34-42.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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