Botanical species · safety record
Trichilia catigua
The EFSA Compendium of Botanicals holds 3 constituent measurements and 3 adverse-effect records for Trichilia catigua. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Trichilia catigua A.Juss.
Regulatory presence
Health Canada's Licensed Natural Health Products Database holds 14 licensed products naming Trichilia catigua as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.
Extract types on licence
Source material stated
What the records describe
Constituents measured
- Alkaloids1
- Lignans1
- Tannins1
Plant parts
- Bark4
- Unspecified2
Preparations
- Solvent extraction4
Effect types
- Neurotoxicity2
- Reproductive1
Target tissues
- Brain2
- Uterus1
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Tannins | Bark | Solvent extraction | 31.43 Percent | HPLC-DAD | Resolve DOI |
| Alkaloids | Unspecified | — | — | Unspecified | No resolvable identifier |
| Lignans | Unspecified | — | — | Unspecified | No resolvable identifier |
Recorded adverse effects
Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.
| Effect | Target tissue | Plant part | Preparation | Test organism | Test type | Source |
|---|---|---|---|---|---|---|
| Neurotoxicity | Brain | Bark | Solvent extraction | House mouse (as animal) | Short-term toxicity | Resolve DOI |
| Neurotoxicity | Brain | Bark | Solvent extraction | House mouse (as animal) | Other | Resolve DOI |
| Reproductive | Uterus | Bark | Solvent extraction | Rat (as animal) | Reproduction toxicity | Resolve DOI |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- dos Santos, AH., Ramos, AC., Silveira, KM., Kiss, ACI., Longhini, R., Diniz, A., de Mello, JCP., Gerardin, DCC. The exposure to Trichilia catigua (catuaba) crude extract impairs fertility of adult female rats but does not cause reproductive damage to male offspring. JOURNAL OF ETHNOPHARMACOLOGY, 2015, vol. 166, p. 86-91. DOI
- Dutra, Rafael C., Campos, Maria M., Santos, Adair R. S., Calixto, Joao B. Medicinal plants in Brazil: Pharmacological studies, drug discovery, challenges and perspectives. Pharmacological Research, 2016.
- Bonassoli, Vivian Taciany., Chassot, Janaine Micheli., Longhini, Renata., Milani, Humberto., Mello, Joao Carlos P., Weffort de Oliveira, Rubia Maria. Subchronic administration of Trichilia catigua ethyl-acetate fraction promotes antidepressant-like effects and increases hippocampal cell proliferation in mice . Journal of ethnopharmacology, 2012, vol. 143, no. 1, p. 179-184. DOI
- Viana, Alice F., Maciel, Izaque S., Motta, Emerson M., Leal, Paulo C., Pianowski, Luiz., Campos, Maria M., Calixto, Joao B. Antinociceptive Activity of Trichilia catigua Hydroalcoholic Extract: New Evidence on Its Dopaminergic Effects . Evidence-based complementary and alternative medicine, 2011, p. 1-8. DOI
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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