Botanical species · safety record

Trichosanthes cucumerina

The EFSA Compendium of Botanicals holds 18 constituent measurements and 2 adverse-effect records for Trichosanthes cucumerina. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Trichosanthes cucumerina L.

18Constituent measurements
2Safety records
9Cited sources
0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

  • Saponins4
  • Alkaloids2
  • Cyanogenic glycosides2
  • Lectins2
  • Tannins2
  • Anthraquinones1
  • Cardiac glycosides1
  • Cucurbitacin b1
  • Oxalic acid1
  • Phytic acid1

Plant parts

  • Fruit unspecified7
  • Seed6
  • Live plants5
  • Leaves2

Preparations

  • Solvent extraction11
  • Powder9

Effect types

  • Reproductive2

Target tissues

  • Urogenital: ovaries2

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
LectinsSeedSolvent extraction350 Milligram/100 gramStandard Chromatographic tests (paper- thin layer- and column chromatography)Resolve DOI
Oxalic acidSeedPowder17.4 Milligram/100 gramResolve DOI
Phytic acidSeedPowder480.03 Milligram/100 gramUnspecifiedResolve DOI
SaponinsSeedPowder2097 Milligram/100 gramUnspecifiedResolve DOI
AlkaloidsLive plantsSolvent extractionPhytochemical screeningNo resolvable identifier
AlkaloidsLeavesSolvent extractionPhytochemical screeningNo resolvable identifier
AnthraquinonesSeedSolvent extractionPhytochemical screeningNo resolvable identifier
Cardiac glycosidesFruit unspecifiedPowderPhytochemical screeningNo resolvable identifier
Cucurbitacin bFruit unspecifiedSolvent extractionStandard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier
Cyanogenic glycosidesFruit unspecifiedPowderPhytochemical screeningNo resolvable identifier
Cyanogenic glycosidesFruit unspecifiedPowder0.43 PercentNo resolvable identifier
LectinsSeedSolvent extractionNo resolvable identifier
SaponinsLive plantsSolvent extractionPhytochemical screeningNo resolvable identifier
SaponinsFruit unspecifiedPowderPhytochemical screeningNo resolvable identifier
SaponinsLeavesSolvent extractionPhytochemical screeningNo resolvable identifier
TanninsFruit unspecifiedPowderPhytochemical screeningNo resolvable identifier
TanninsLive plantsSolvent extractionPhytochemical screeningNo resolvable identifier
Trypsin inhibitorsFruit unspecifiedPowder8.43 International Unit/gramNo resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

EffectTarget tissuePlant partPreparationTest organismTest typeSource
ReproductiveUrogenital: ovariesLive plantsSolvent extractionRat (as animal)Reproduction toxicityNo resolvable identifier
ReproductiveUrogenital: ovariesLive plantsSolvent extractionRat (as animal)Reproduction toxicityNo resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Ojiako, O.A., Igwe, C.U. The nutritive, anti-nutritive and hepatotoxic properties of Trichosanthes anguina (snake tomato) fruits from Nigeria. Pakistan journal of nutrition, 2008, vol. 7, no. 1, p. 85-89.
  2. Kage, Devendra N., Malashetty, Vijaykumar B., Seetharam, Y. N., Suresh, P., Patil, Saraswati B. Effect of Ethanol Extract of Whole Plant of Trichosanthes cucumerina var. cucumerina L. on Gonadotropins, Ovarian Follicular Kinetics and Estrous Cycle for Screening of Antifertility Activity in Albino Rats . International journal of morphology, 2009, vol. 27, no. 1, p. 173-182.
  3. Ilelaboye, N.O.A., Pikuda, O.O. Determination of minerals and anti-nutritional factors of some lesser-known crop seeds. Pakistan Journal of Nutrition, 2009, vol. 8, no. 10, p. 1652-1656. DOI
  4. Silapa-Archa, Weena., Picha, Porntipa., Lurwongrattana, Oudsanee., Kittiwongsunthorn, Worawit., Ungsuntnornsarit, Pichai. Investigation of the triterpenes of Cucurbitaceae prevalent in Thailand. Warasan phesatchasat, 1981, p. 5-8.
  5. Oketunde, F. O., Tor-Anyiin, A. T., Rebok, J. M. Extraction and characterization of Trichosanthes cucumerina linn (snake gourd) seed oil. Journal of chemical society of nigeria, 2011, p. 115-117.
  6. Franca, O.N. Antinutritional evaluation and in vitro protein digestibility of some Nigerian cucurbits. Pakistan Journal of Nutrition, 2012, vol. 11, no. 3, p. 208-210.
  7. Seshagirirao, K., Leelavathi, C., Sasidhar, V. Cross-linked leucaena seed gum matrix: An affinity chromatography tool for galactose-specific lectins. Journal of biochemistry and molecular biology, 2005, vol. 38, no. 3, p. 370-372.
  8. Padma, P., Komath, SS., Nadimpalli, SK., Swamy, MJ. Purification in high yield and characterisation of a new galactose-specific lectin from the seeds of Trichosanthes cucumerina . Phytochemistry, 1999, vol. 50, no. 3, p. 363-371. DOI
  9. Sandhya, S., Chandrasekhar, J., Banji, David., Rao, K. N. V. Pharmacognostical study on the leaf of Tricosanthes Cucumerina Linn. Archives of applied science research, 2010, p. 414-421.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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