Botanical species · safety record
Trichosanthes kirilowii
The EFSA Compendium of Botanicals holds 4 constituent measurements for Trichosanthes kirilowii. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Trichosanthes kirilowii Maxim.
Regulatory presence
Health Canada's Licensed Natural Health Products Database holds 428 licensed products naming Trichosanthes kirilowii as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.
Extract types on licence
Source material stated
What the records describe
Constituents measured
- Cucurbitacin b2
- Lignans1
- Trichosanthin1
Plant parts
- Roots and other underground parts1
- Roots and other underground parts used as staple food1
- Seed1
- Unspecified1
Preparations
- Solvent extraction3
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Cucurbitacin b | Unspecified | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Cucurbitacin b | Roots and other underground parts | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Lignans | Seed | — | — | Unspecified | Resolve DOI |
| Trichosanthin | Roots and other underground parts used as staple food | Solvent extraction | — | Chromatographic tests | Resolve DOI |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Ding, Xiuli., Chi, Jiadong., Yang, Xue., Hao, Jian., Liu, Chang., Zhu, Cuihong., Wang, Xiaodong., Liu, Xiaohui., Niu, Yangyang., Ji, Wei., Chen, Dan., Wu, Xiongzhi. Cucurbitacin B synergistically enhances the apoptosis-inducing effect of arsenic trioxide by inhibiting STAT3 phosphorylation in lymphoma Ramos cells . Leukemia & lymphoma, 2017, vol. 58, no. 10, p. 2439-2451. DOI
- Ryu, Shi Yong., Lee, Seung Ho., Choi, San Un., Lee, Chong Ock., No, Zaesung., Ahn, Jong Woong. Antitumor activity of Trichosanthes kirilowii. Archives of pharmacal research (seoul), 1994, vol. 17, no. 5, p. 348-353. DOI
- Lee, Eunyoung., Ahamed, V. S. Jamal., Kumar, Mahto Sanjeev., Rhee, Seog Woo., Moon, Surk-Sik., Hong, In Seok. Synthesis and evaluation of cytotoxic effects of hanultarin and its derivatives . Bioorganic & medicinal chemistry letters, 2011, vol. 21, no. 21, p. 6245-6248. DOI
- CHAN, WY., NG, TB., WU, PJ., YEUNG, HW. DEVELOPMENTAL TOXICITY AND TERATOGENICITY OF TRICHOSANTHIN, A RIBOSOME-INACTIVATING PROTEIN, IN MICE . Teratogenesis carcinogenesis and mutagenesis, 1993, vol. 13, no. 2, p. 47-57. DOI
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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