Botanical species · safety record
Tylophora asthmatica
The EFSA Compendium of Botanicals holds 14 constituent measurements and 1 adverse-effect record for Tylophora asthmatica. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Tylophora asthmatica Wight. & Arn.
Regulatory presence
No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.
What the records describe
Constituents measured
- Alkaloids6
- Tylophorine4
- Gamma fagarine1
- Skimmianine1
- Tannins1
- Tylophorinine1
Plant parts
- Leaves5
- Live plants4
- Stem3
- stalk3
- Roots and other underground parts2
- Aerial part of plants1
Preparations
- Solvent extraction13
Effect types
- Hepatotoxicity1
Target tissues
- Liver1
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Gamma fagarine | Live plants | — | — | Standard Chromatographic tests (paper- thin layer- and column chromatography) | Resolve DOI |
| Skimmianine | Live plants | — | — | Standard Chromatographic tests (paper- thin layer- and column chromatography) | Resolve DOI |
| Tylophorine | Stem / stalk | Solvent extraction | 0.008 Percent | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Tylophorine | Live plants | Solvent extraction | — | Chromatographic tests | Resolve DOI |
| Tylophorine | Leaves | Solvent extraction | ≤ 0.074 Percent | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Tylophorine | Leaves | Solvent extraction | ≥ 0.012 Percent | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Tylophorinine | Live plants | Solvent extraction | — | Chromatographic tests | Resolve DOI |
| Alkaloids | Leaves | Solvent extraction | ≥ 0.12 Percent | Traditional analytical techniques (wet chemical tests) | No resolvable identifier |
| Alkaloids | Leaves | Solvent extraction | ≤ 0.45 Percent | Traditional analytical techniques (wet chemical tests) | No resolvable identifier |
| Alkaloids | Roots and other underground parts | Solvent extraction | ≥ 0.09 Percent | Traditional analytical techniques (wet chemical tests) | No resolvable identifier |
| Alkaloids | Roots and other underground parts | Solvent extraction | ≤ 0.35 Percent | Traditional analytical techniques (wet chemical tests) | No resolvable identifier |
| Alkaloids | Stem / stalk | Solvent extraction | ≥ 0.07 Percent | Traditional analytical techniques (wet chemical tests) | No resolvable identifier |
| Alkaloids | Stem / stalk | Solvent extraction | ≤ 0.37 Percent | Traditional analytical techniques (wet chemical tests) | No resolvable identifier |
| Tannins | Aerial part of plants | Solvent extraction | — | Phytochemical screening | No resolvable identifier |
Recorded adverse effects
Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.
| Effect | Target tissue | Plant part | Preparation | Test organism | Test type | Source |
|---|---|---|---|---|---|---|
| Hepatotoxicity | Liver | Leaves | Solvent extraction | Rat (as animal) | Short-term toxicity | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Gupta, R., Datta, A., Shri, R. Extraction process optimization of tylophorine from Tylophora asthmatica Wight & Arn.. Pharmacognosy Journal, 2012, vol. 4, no. 28, p. 19-23. DOI
- Govindachari, T.R., Pai, B.R., Nagarajan, K. Chemical examination of tylophora asthmatica. Part I. Journal of the Chemical Society (Resumed), 1954, p. 2801-2803. DOI
- Malathi, R., Gomaz, P. Evaluation of preliminary toxicity studies on the methanolic leaves extract of Tylophora asthmatica in experimental rats. Journal of pharmacology and toxicology, 2008, vol. 3, no. 1, p. 34-40.
- Karnick, C. R. Phytochemical investigations of some Tylophora species found in India. Planta Medica, 1975, p. 333-336.
- ETHERINGTON, T., HERBERT, RB., JACKSON, FB. FUROQUINOLINE ALKALOIDS FROM TYLOPHORA-ASTHMATICA. Phytochemistry, 1977, vol. 16, no. 7, p. 1125-1126. DOI
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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