Botanical species · safety record

Tylophora asthmatica

The EFSA Compendium of Botanicals holds 14 constituent measurements and 1 adverse-effect record for Tylophora asthmatica. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Tylophora asthmatica Wight. & Arn.

14Constituent measurements
1Safety records
5Cited sources
0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

  • Alkaloids6
  • Tylophorine4
  • Gamma fagarine1
  • Skimmianine1
  • Tannins1
  • Tylophorinine1

Plant parts

  • Leaves5
  • Live plants4
  • Stem3
  • stalk3
  • Roots and other underground parts2
  • Aerial part of plants1

Preparations

  • Solvent extraction13

Effect types

  • Hepatotoxicity1

Target tissues

  • Liver1

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
Gamma fagarineLive plantsStandard Chromatographic tests (paper- thin layer- and column chromatography)Resolve DOI
SkimmianineLive plantsStandard Chromatographic tests (paper- thin layer- and column chromatography)Resolve DOI
TylophorineStem / stalkSolvent extraction0.008 PercentHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
TylophorineLive plantsSolvent extractionChromatographic testsResolve DOI
TylophorineLeavesSolvent extraction≤ 0.074 PercentHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
TylophorineLeavesSolvent extraction≥ 0.012 PercentHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
TylophorinineLive plantsSolvent extractionChromatographic testsResolve DOI
AlkaloidsLeavesSolvent extraction≥ 0.12 PercentTraditional analytical techniques (wet chemical tests)No resolvable identifier
AlkaloidsLeavesSolvent extraction≤ 0.45 PercentTraditional analytical techniques (wet chemical tests)No resolvable identifier
AlkaloidsRoots and other underground partsSolvent extraction≥ 0.09 PercentTraditional analytical techniques (wet chemical tests)No resolvable identifier
AlkaloidsRoots and other underground partsSolvent extraction≤ 0.35 PercentTraditional analytical techniques (wet chemical tests)No resolvable identifier
AlkaloidsStem / stalkSolvent extraction≥ 0.07 PercentTraditional analytical techniques (wet chemical tests)No resolvable identifier
AlkaloidsStem / stalkSolvent extraction≤ 0.37 PercentTraditional analytical techniques (wet chemical tests)No resolvable identifier
TanninsAerial part of plantsSolvent extractionPhytochemical screeningNo resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

EffectTarget tissuePlant partPreparationTest organismTest typeSource
HepatotoxicityLiverLeavesSolvent extractionRat (as animal)Short-term toxicityNo resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Gupta, R., Datta, A., Shri, R. Extraction process optimization of tylophorine from Tylophora asthmatica Wight & Arn.. Pharmacognosy Journal, 2012, vol. 4, no. 28, p. 19-23. DOI
  2. Govindachari, T.R., Pai, B.R., Nagarajan, K. Chemical examination of tylophora asthmatica. Part I. Journal of the Chemical Society (Resumed), 1954, p. 2801-2803. DOI
  3. Malathi, R., Gomaz, P. Evaluation of preliminary toxicity studies on the methanolic leaves extract of Tylophora asthmatica in experimental rats. Journal of pharmacology and toxicology, 2008, vol. 3, no. 1, p. 34-40.
  4. Karnick, C. R. Phytochemical investigations of some Tylophora species found in India. Planta Medica, 1975, p. 333-336.
  5. ETHERINGTON, T., HERBERT, RB., JACKSON, FB. FUROQUINOLINE ALKALOIDS FROM TYLOPHORA-ASTHMATICA. Phytochemistry, 1977, vol. 16, no. 7, p. 1125-1126. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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