Botanical species · safety record

Uncaria gambir

The EFSA Compendium of Botanicals holds 5 constituent measurements and 1 adverse-effect record for Uncaria gambir. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Uncaria gambir (Hunter) Roxb.

5Constituent measurements

1Safety records

6Cited sources

8Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 8 licensed products naming Uncaria gambir as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Source material stated

Branch(es)
Senegalia catechu - Branch
Stem
Whole plant(s)

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Alkaloids	Unspecified	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	No resolvable identifier
Indole alkaloids	Leaves	Solvent extraction	120 Milligram/kilogram	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Indole alkaloids	Leaves	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	No resolvable identifier
Indole alkaloids	Stem / stalk	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Phlobotannins	Leaves	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Digestive	Digestive	Leaves	Solvent extraction	—	In vitro	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Hathway, D. E., Seakins, J. W. T. Enzymic oxidation of catechin to a polymer structurally related to some phlobatannins. Biochemical Journal, 1957, p. 239-245.
Merlini, Lucio., Mondelli, R., Nasini, Gianluca., Hesse, M. Structure of roxburghines A-E, new indole alkaloids from an Uncaria Sp. Tetrahedron, 1970, p. 2259-2279.
Merlini, Lucio., Mondelli, Rosanna., Nasini, Gianluca., Hesse, Manfred. Gambirine, a new indole alkaloid from Uncaria gambier. Tetrahedron Letters, 1967, p. 1571-1575.
CHAN, KC. GAMBIRDINE AND ISOGAMBIRDINE ALKALOIDS FROM UNCARIA GAMBIR (HUNT) ROXB. TETRAHEDRON LETTERS, 1968, no. 30, p. 3403-&.
Taylor, William Irving., Hamet, Raymond. Ourouparine, an alkaloid of Ourouparia gambir. Comptes rendus des seances de l'academie des sciences, serie d: sciences naturelles, 1966, p. 1141-1143.
Apea-Bah, F. B., Hanafi, M., Dewi, R. T., Fajriah, S., Darwaman, A., Artanti, N., Lotulung, P., Ngadymang, P., Minarti, B. Assessment of the DPPH and alpha-glucosidase inhibitory potential of gambier and qualitative identification of major bioactive compound . Journal of medicinal plants research, 2009, vol. 3, no. 10, p. 736-757.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature