Botanical species · safety record

Urena lobata

The EFSA Compendium of Botanicals holds 8 constituent measurements and 4 adverse-effect records for Urena lobata. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Urena lobata L.

8Constituent measurements
4Safety records
7Cited sources
0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

  • Alkaloids2
  • Saponins2
  • Cyanide1
  • Imperatorin1
  • Phytic acid1
  • Tannins1

Plant parts

  • Leaves7
  • Roots and other underground parts5

Preparations

  • Solvent extraction8
  • Fresh2

Effect types

  • Hepatotoxicity3
  • Reproductive1

Target tissues

  • Liver3
  • Testes1

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
AlkaloidsLeavesSolvent extractionPhytochemical screeningNo resolvable identifier
AlkaloidsLeavesFresh8.19 PercentPhytochemical screeningNo resolvable identifier
CyanideLeaves1.52 Milligram/gramUnspecifiedNo resolvable identifier
ImperatorinRoots and other underground partsSolvent extractionColorimetry, Spectroscopy (Spectrometry) and PhotometryNo resolvable identifier
Phytic acidLeaves13.8 Milligram/gramUnspecifiedNo resolvable identifier
SaponinsLeavesSolvent extractionPhytochemical screeningNo resolvable identifier
SaponinsLeavesFresh3.63 PercentPhytochemical screeningNo resolvable identifier
TanninsLeavesSolvent extractionPhytochemical screeningNo resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

EffectTarget tissuePlant partPreparationTest organismTest typeSource
ReproductiveTestesRoots and other underground partsSolvent extractionRat (as animal)Reproduction toxicityResolve DOI
HepatotoxicityLiverRoots and other underground partsSolvent extractionRat (as animal)Short-term toxicityNo resolvable identifier
HepatotoxicityLiverRoots and other underground partsSolvent extractionRabbit (as animal)SubchronicNo resolvable identifier
HepatotoxicityLiverRoots and other underground partsSolvent extractionRat (as animal)Short-term toxicityNo resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Islam, Md. Hasibul., Rahman, K. M. Hasanur., Rahman, Shahnaz., Rahmatullah, Mohammed. Preliminary antihyperglycemic, antinociceptive activity, phytochemical analysis and toxicity studies on leaves of Urena lobata L.. Journal of chemical and pharmaceutical research, 2015, p. 559-563.
  2. Abii, T. A., Onuha, E. N. A preliminary investigation into the phytochemicals, vitamins and mineral constituents of the leaf of two tradomedicinal plants - urena lobata and cassia alata used in Nigeria. IOSR Journal of Applied Chemistry, 2014, p. 1-4.
  3. Okoli, I.C., Anunobi, M.O., Obua, B.E., Enemuo, V. Studies on selected browses of southeastern Nigeria with particular reference to their proximate and some endogenous anti-nutritional constituents. Livestock Research for Rural Development, 2003, vol. 15, no. 9, p. 1-8.
  4. Omonkhua, Akhere A., Onoagbe, Iyere O. Evaluation of the long-term effects of Urena lobata root extracts on blood glucose and hepatic function of normal rabbits. Journal of toxicology and environmental health sciences, 2011, p. 204-213.
  5. Mshelia, I.Y., Dalori, B.M., Hamman, L.L., Garba, S.H. Effect of the aqueous root extract of Urena lobata (linn) on the liver of albino rat. Research Journal of Applied Sciences, Engineering and Technology, 2013, vol. 5, no. 1, p. 1-6.
  6. Ghosh, Keshab. A furocoumarin, Imperatorin isolated from Urena lobata L.. Molbank, 2004.
  7. Dhanapal, Ramaiyan., Ratna, J. Vijaya., Gupta, Malaya., Sarathchandran, I. Preliminary study on antifertility activity of Enicostemma axillare leaves and Urena lobata root used in Indian traditional folk medicine . Asian pacific journal of tropical medicine, 2012, vol. 5, no. 8, p. 616-622. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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