Botanical species · safety record
Urena lobata
The EFSA Compendium of Botanicals holds 8 constituent measurements and 4 adverse-effect records for Urena lobata. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Urena lobata L.
Regulatory presence
No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.
What the records describe
Constituents measured
- Alkaloids2
- Saponins2
- Cyanide1
- Imperatorin1
- Phytic acid1
- Tannins1
Plant parts
- Leaves7
- Roots and other underground parts5
Preparations
- Solvent extraction8
- Fresh2
Effect types
- Hepatotoxicity3
- Reproductive1
Target tissues
- Liver3
- Testes1
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Alkaloids | Leaves | Solvent extraction | — | Phytochemical screening | No resolvable identifier |
| Alkaloids | Leaves | Fresh | 8.19 Percent | Phytochemical screening | No resolvable identifier |
| Cyanide | Leaves | — | 1.52 Milligram/gram | Unspecified | No resolvable identifier |
| Imperatorin | Roots and other underground parts | Solvent extraction | — | Colorimetry, Spectroscopy (Spectrometry) and Photometry | No resolvable identifier |
| Phytic acid | Leaves | — | 13.8 Milligram/gram | Unspecified | No resolvable identifier |
| Saponins | Leaves | Solvent extraction | — | Phytochemical screening | No resolvable identifier |
| Saponins | Leaves | Fresh | 3.63 Percent | Phytochemical screening | No resolvable identifier |
| Tannins | Leaves | Solvent extraction | — | Phytochemical screening | No resolvable identifier |
Recorded adverse effects
Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.
| Effect | Target tissue | Plant part | Preparation | Test organism | Test type | Source |
|---|---|---|---|---|---|---|
| Reproductive | Testes | Roots and other underground parts | Solvent extraction | Rat (as animal) | Reproduction toxicity | Resolve DOI |
| Hepatotoxicity | Liver | Roots and other underground parts | Solvent extraction | Rat (as animal) | Short-term toxicity | No resolvable identifier |
| Hepatotoxicity | Liver | Roots and other underground parts | Solvent extraction | Rabbit (as animal) | Subchronic | No resolvable identifier |
| Hepatotoxicity | Liver | Roots and other underground parts | Solvent extraction | Rat (as animal) | Short-term toxicity | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Islam, Md. Hasibul., Rahman, K. M. Hasanur., Rahman, Shahnaz., Rahmatullah, Mohammed. Preliminary antihyperglycemic, antinociceptive activity, phytochemical analysis and toxicity studies on leaves of Urena lobata L.. Journal of chemical and pharmaceutical research, 2015, p. 559-563.
- Abii, T. A., Onuha, E. N. A preliminary investigation into the phytochemicals, vitamins and mineral constituents of the leaf of two tradomedicinal plants - urena lobata and cassia alata used in Nigeria. IOSR Journal of Applied Chemistry, 2014, p. 1-4.
- Okoli, I.C., Anunobi, M.O., Obua, B.E., Enemuo, V. Studies on selected browses of southeastern Nigeria with particular reference to their proximate and some endogenous anti-nutritional constituents. Livestock Research for Rural Development, 2003, vol. 15, no. 9, p. 1-8.
- Omonkhua, Akhere A., Onoagbe, Iyere O. Evaluation of the long-term effects of Urena lobata root extracts on blood glucose and hepatic function of normal rabbits. Journal of toxicology and environmental health sciences, 2011, p. 204-213.
- Mshelia, I.Y., Dalori, B.M., Hamman, L.L., Garba, S.H. Effect of the aqueous root extract of Urena lobata (linn) on the liver of albino rat. Research Journal of Applied Sciences, Engineering and Technology, 2013, vol. 5, no. 1, p. 1-6.
- Ghosh, Keshab. A furocoumarin, Imperatorin isolated from Urena lobata L.. Molbank, 2004.
- Dhanapal, Ramaiyan., Ratna, J. Vijaya., Gupta, Malaya., Sarathchandran, I. Preliminary study on antifertility activity of Enicostemma axillare leaves and Urena lobata root used in Indian traditional folk medicine . Asian pacific journal of tropical medicine, 2012, vol. 5, no. 8, p. 616-622. DOI
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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