Botanical species · safety record

Valeriana officinalis

The EFSA Compendium of Botanicals holds 2 constituent measurements and 1 genotoxicity assay for Valeriana officinalis. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Valeriana officinalis L.

2Constituent measurements

1Safety records

3Cited sources

990Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 990 licensed products naming Valeriana officinalis as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Dry
Extract Type TBA
Fresh
fluid
solid

Source material stated

Dried rhizome
Dried root(s)
Dried, whole or fragmented underground parts, comprising the rhizome, roots, and stolons
Fresh root(s)
Fresh underground organ of Valeriana officinalis L.
New material
Plante entière
Racine

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Alkaloids	Unspecified	Solvent extraction	—	Unspecified	Resolve DOI
Baldrinal	Unspecified	Solvent extraction	—	Unspecified	No resolvable identifier

Genotoxicity testing

Outcomes of genotoxicity assays as recorded in the source. A negative assay is a result under those test conditions, not a clearance.

Outcome	Endpoint	Test	Tested organism	Metabolic activation	Source
Positive	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	Human (as organism)	Not applicable	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

isanghyeob., baghyeonjeong. Studies on the Components of Valerian and Isovaleramide. Yakhak hoeji, 2010, vol. 54, no. 1, p. 1-7.
Wang, HL., Zhang, DF., Luo, ZF., Lou, Y., Li, QR., Wang, YZ. In vitro study on the genotoxicity of dichloromethane extracts of valerian (DEV) in human endothelial ECV304 cells and the effect of vitamins E and C in attenuating the DEV-induced DNA damages . Toxicology and applied pharmacology, 2003, vol. 188, no. 1, p. 36-41. DOI
Patocka, Jiri., Jaki, Jiri. Biomedically relevant chemical constituents of Valeriana officinalis. Journal of applied biomedicine, 2010, vol. 8, no. 1, p. 11-18. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature