Botanical species · safety record

Vinca major

The EFSA Compendium of Botanicals holds 10 constituent measurements for Vinca major. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Vinca major L.

10Constituent measurements

0Safety records

9Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
10-methoxytetrahydroalstonine	Live plants	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Alkaloids	Aerial part of plants	Solvent extraction	—	IR and Raman Spectroscopy	Resolve DOI
Indole alkaloids	Aerial part of plants	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Indole alkaloids	Live plants	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Indole alkaloids	Live plants	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Indole alkaloids	Live plants	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Indole alkaloids	Unspecified	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Pyridine alkaloids	Aerial part of plants	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Syringaresinol	Leaves	Solvent extraction	—	HPLC with standard detection methods	Resolve DOI
Indole alkaloids	Aerial part of plants	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Sohretoglu, Didem., Masullo, Milena., Piacente, Sonia., Kirmizibekmez, Hasan. Iridoids, monoterpenoid glucoindole alkaloids and flavonoids from Vinca major . Biochemical systematics and ecology, 2013, vol. 49, p. 69-72. DOI
Il'yashenko, L.I., Malikov, V.M., Yagudaev, M.R., Yunusov, S.Yu. Alkaloids of Vinca major. Chemistry of natural compounds, 1977, vol. 13, no. 3, p. 324-327. DOI
Bahadori, Fatemeh., Topcu, Gulacti., Boga, Mehmet., Turkekul, Ayla., Kolak, Ufuk., Kartal, Murat. Indole Alkaloids from Vinca major and V. minor Growing in Turkey. Natural product communications, 2012, vol. 7, no. 6, p. 731-734.
Wei, Xin., Khan, Afsar., Song, Da., Dai, Zhi., Liu, Ya-Ping., Yu, Hao-Fei., Wang, Bei., Zhu, Pei-Feng., Ding, Cai-Feng., Zhao, Xu-Dong., Wang, Yi-Fen., Luo, Xiao-Dong. Three New Pyridine Alkaloids from Vinca major Cultivated in Pakistan. Natural products and bioprospecting, 2017, vol. 7, no. 4, p. 323-327. DOI
Atta-Ur-Rahman, Abida Sultana., Nighat, Farzana., Bhatti, M. Khalid., Kurucu, Semra., Kartal, Murat. Alkaloids from Vinca major. Phytochemistry (oxford), 1995, vol. 38, no. 4, p. 1057-1061. DOI
Zhang, Zhi-Jun., Du, Ru-Nan., He, Juan., Wu, Xing-De., Li, Yan., Li, Rong-Tao., Zhao, Qin-Shi. Vinmajorines C-E, Monoterpenoid Indole Alkaloids from Vinca major. Helvetica chimica acta, 2016, vol. 99, no. 2, p. 157-160. DOI
Zhang, Zhi-Jun., Du, Ru-Nan., He, Juan., Wu, Xing-De., Li, Yan., Li, Rong-Tao., Zhao, Qin-Shi. Three new monoterpenoid indole alkaloids from Vinca major. Journal of asian natural products research, 2016, vol. 18, no. 4, p. 328-333. DOI
MUKHOPADHYAY, G., MUKHERJEE, B., PATRA, A., CHATTERJEE, A., GHOSH, R., ROYCHOWDHURY, P., KAWAZURA, H. 11-METHOXYTETRAHYDROALSTONINE, A HETEROYOHIMBINOID ALKALOID FROM VINCA-MAJOR . Phytochemistry, 1991, vol. 30, no. 7, p. 2447-2449. DOI
Cheng, Gui-Guang., Zhao, Yun-Li., Zhang, Yu., Lunga, Paul-Keilah., Hu, Dong-Bao., Li, Yan., Gu, Ji., Song, Chang-Wei., Sun, Wei-Bang., Liu, Ya-Ping., Luo, Xiao-Dong. Indole alkaloids from cultivated Vinca major. Tetrahedron, 2014, vol. 70, no. 45, p. 8723-8729. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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