Botanical species · safety record

Vincetoxicum hirundinaria

The EFSA Compendium of Botanicals holds 17 constituent measurements for Vincetoxicum hirundinaria. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Vincetoxicum hirundinaria Medik.

17Constituent measurements

0Safety records

6Cited sources

4Licensed products (Canada)

Also recorded as

Asclepias vincetoxicum L.
Cynanchum vincetoxicum (L.) Pers.

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 4 licensed products naming Vincetoxicum hirundinaria as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Source material stated

Fresh leaf
Fresh leaves
Root

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
2-hydroxyacetophenone	Roots and other underground parts	Essential oil	84 Percent	GC-MS	Resolve DOI
2-hydroxyacetophenone	Roots and other underground parts	—	0.06 Percent	Nuclear Magnetic Resonance (NMR)	Resolve DOI
4-hydroxyacetophenone	Roots and other underground parts	—	0.012 Percent	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Alkaloids	Aerial part of plants	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Antofine n-oxide derivatives	Bark	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Apiole	Roots and other underground parts	Essential oil	1 Percent	GC-MS	Resolve DOI
Hirundicoside b	Roots and other underground parts	—	3e-04 Percent	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Hirundicoside c	Roots and other underground parts	—	2e-04 Percent	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Hirundicoside d	Roots and other underground parts	—	2e-04 Percent	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Indole alkaloids	Leaves	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Indole alkaloids	Bark	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Pregnane derivatives	Roots and other underground parts	—	4e-04 Percent	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Pregnane derivatives	Roots and other underground parts	—	0.0025 Percent	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Tylophorine	Aerial part of plants	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Anhydrohirundigenin	Unspecified	—	—	Unspecified	No resolvable identifier
Antofine n-oxide derivatives	Live plants	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Hirundoside a	Unspecified	—	—	Unspecified	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Lavault, M., Richomme, P., Bruneton, J. Acetophenones and new pregnane glycosides from the roots of Vincetoxicum hirundinaria . Fitoterapia, 1999, vol. 70, no. 2, p. 216-220. DOI
Stoeckel, K., Reichstein, Tadeus. Glycosides of Vincetoxicum hirundinaria. Scientia pharmaceutica, 1969, vol. 37, no. 1, p. 47-9.
Staerk, D., Lykkeberg, AK., Christensen, J., Budnik, BA., Abe, F., Jaroszewski, JW. In vitro cytotoxic activity of phenanthroindolizidine alkaloids from Cynanchum vincetoxicum and Tylophora tanakae against drug-sensitive and multidrug-resistant cancer cells . Journal of natural products, 2002, vol. 65, no. 9, p. 1299-1302. DOI
Lavault, M., Richomme, P., Bruneton, J. New phenatroindolizidine N-oxides alkaloids isolated from Vincetoxicum hirudinaria medic.. Pharmaceutica acta helvetiae, 1994, vol. 68, no. 4, p. 225-227. DOI
TANNER, U., WIEGREBE, W. ALKALOIDS OF CYNANCHUM-VINCETOXICUM - EFFICACY AGAINST MDA-MB-231 MAMMARY-CARCINOMA CELLS . Archiv der pharmazie, 1993, vol. 326, no. 2, p. 67-72. DOI
Bour, Tania., Yang, Xianwen., Li, Weihong., Bernardin, Franois., Kaoma, Tony., Muller, Arnaud., Vallar, Laurent., Steinmetz, Andre. Differential Effects of Antofine N-Oxide on Solid Tumor and Leukemia Cells . Anti-cancer agents in medicinal chemistry, 2014, vol. 14, no. 10, p. 1315-1323.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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