Botanical species · safety record

Withania coagulans

The EFSA Compendium of Botanicals holds 9 constituent measurements and 4 adverse-effect records for Withania coagulans. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Withania coagulans (Stocks) Dunal

9Constituent measurements

4Safety records

7Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Lignans	Live plants	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Alkaloids	Live plants	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Alkaloids	Fruit unspecified	Solvent extraction	—	Unspecified	No resolvable identifier
Alkaloids	Fruit unspecified	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Anthraquinones	Live plants	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Cardiac glycosides	Live plants	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Saponins	Live plants	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Tannic acid	Live plants	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Withanolides	Leaves	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Digestive	Digestive: pancreas	Unspecified	—	—	In vitro	No resolvable identifier
Neurotoxicity	Neurologic: central nervous system	Fruit unspecified	Solvent extraction	Rat (as animal)	Acute toxicity	No resolvable identifier
Neurotoxicity	Neurologic: central nervous system	Fruit unspecified	—	Rat (as animal)	Acute toxicity	No resolvable identifier
Neurotoxicity	Neurologic: central nervous system	Fruit unspecified	Solvent extraction	Rat (as animal)	Acute toxicity	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Khan, Farhat Ali., Hussain, Iqbal., Farooq, Shahid., Ahmad, Majed., Arif, Muhammad., Ur Rehman, Inayat. Phytochemical screening of some Pakistanian medicinal plants. Middle East Journal of Scientific Research, 2011, p. 575-578.
Sharma, R., Arya, V. A review on fruits having anti-diabetic potential. Journal of chemical and pharmaceutical research, 2011, vol. 3, no. 2, p. 204-212.
Lamba, Harminder Singh., Bhargava, Chandra Shekhar., Bhargava, Shilpi. IN VITRO alpha-GLUCOSIDASE AND ALDOSE REDUCTASE ACTIVITY AND IN VIVO ANTI-DIABETIC ACTIVITY OF WITHANIA COAGULANS . Indian journal of natural products, 2011, vol. 27, no. 1, p. 14-18.
Nur-e-Alam, M., Yousaf, M., Qureshi, S., Baig, I., Nasim, S., Atta-ur-Rahman., Choudhary, MI. A novel dimeric podophyllotoxin-type lignan and a new withanolide from Withania coagulans. HELVETICA CHIMICA ACTA, 2003, vol. 86, no. 3, p. 607-614. DOI
Subramanian, S. Sankara., Sethi, P. D. Steroidal components of Withania coagulans leaves. Indian journal of pharmacy, 1971, p. 40-41.
Atal, C. K., Sethi, P. D. A preliminary chemical examination of Withania coagulans. Indian journal of pharmacy, 1963, p. 163-164.
BUDHIRAJA, RD., BALA, S., GARG, KN. PHARMACOLOGICAL INVESTIGATIONS ON FRUITS OF WITHANIA-COAGULANS-DUNAL. Planta medica, 1977, vol. 32, no. 2, p. 154-157.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature