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Botanical species · safety record

Withania somnifera

The EFSA Compendium of Botanicals holds 5 constituent measurements for Withania somnifera. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Withania somnifera (L.) Dunal

5Constituent measurements
0Safety records
4Cited sources
2,719Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 2,719 licensed products naming Withania somnifera as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

  • Dry
  • Extract Type TBA
  • Fresh

Source material stated

  • Dried root(s)
  • Fresh root(s)
  • Herb top and root
  • Hydroxocobalamin
  • Isolated from Griffonia seed
  • Leaf
  • Leaf extract
  • Leaf/Leaves

What the records describe

Constituents measured

  • Alkaloids1
  • Epoxides1
  • Oxalates1
  • Saponins1
  • Withanolides1

Plant parts

  • Leaves2
  • Aerial part of plants1
  • Roots and other underground parts1
  • Unspecified1

Preparations

  • Solvent extraction3

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
EpoxidesLeavesSolvent extraction—HPLC with standard detection methodsResolve DOI
OxalatesAerial part of plants——UnspecifiedResolve DOI
SaponinsLeavesSolvent extraction—HPLC with standard detection methodsResolve DOI
AlkaloidsUnspecified——UnspecifiedNo resolvable identifier
WithanolidesRoots and other underground partsSolvent extraction—UnspecifiedNo resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Gehlot, Meenu., Kasera, Pawan K., Hussain, Shahdab. Seasonal variations in total alkaloids and phenols in Withania species from arid region. Journal of medicinal and aromatic plant sciences, 2011, p. 404-406.
  2. Jayaprakasam, B., Zhang, YJ., Seeram, NP., Nair, MG. Growth inhibition of human tumor cell lines by withanolides from Withania somnifera leaves. LIFE SCIENCES, 2003, vol. 74, no. 1, p. 125-132. DOI
  3. DOAIGEY, AR. OCCURRENCE, TYPE, AND LOCATION OF CALCIUM-OXALATE CRYSTALS IN LEAVES AND STEMS OF 16 SPECIES OF POISONOUS PLANTS. AMERICAN JOURNAL OF BOTANY, 1991, vol. 78, no. 12, p. 1608-1616. DOI
  4. Pomilio, Alicia B., Falzoni, Elvira M., Vitale, Arturo A. Toxic chemical compounds of the Solanaceae. Natural product communications, 2008, vol. 3, no. 4, p. 593-628.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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