Botanical species · safety record

Xanthium spinosum

The EFSA Compendium of Botanicals holds 11 constituent measurements and 1 adverse-effect record for Xanthium spinosum. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Xanthium spinosum L.

11Constituent measurements

1Safety records

6Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Atractyloside	Aerial part of plants	Solvent extraction	—	Nuclear Magnetic Resonance (NMR) and Electron Spin Resonance (ESR) spectroscopy	Resolve DOI
Atractyloside	Aerial part of plants	Solvent extraction	—	Nuclear Magnetic Resonance (NMR) and Electron Spin Resonance (ESR) spectroscopy	Resolve DOI
Beta-selinene	Aerial part of plants	Essential oil	≥ 0.2 Percent	GC-MS	Resolve DOI
Beta-selinene	Aerial part of plants	Essential oil	≤ 1.9 Percent	GC-MS	Resolve DOI
Cadalene	Aerial part of plants	Essential oil	≥ 3.1 Percent	GC-MS	Resolve DOI
Cadalene	Aerial part of plants	Essential oil	≤ 8.1 Percent	GC-MS	Resolve DOI
Carboxyatractyloside	Aerial part of plants	Solvent extraction	—	Nuclear Magnetic Resonance (NMR) and Electron Spin Resonance (ESR) spectroscopy	Resolve DOI
Myrcene	Aerial part of plants	Essential oil	≤ 2.2 Percent	GC-MS	Resolve DOI
Xanthatin	Aerial part of plants	Solvent extraction	—	Chromatographic tests	Resolve DOI
Cardenolide glycosides	Bark	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Tannins	Leaves	—	—	—	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Hepatotoxicity	Liver	Leaves	—	Rat (as animal)	Short-term toxicity	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Silvero-Isidre, Arturo., Morinigo-Guayuan, Sergio., Meza-Ojeda, Aaron., Mongelos-Cardozo, Marcelo., Gonzalez-Ayala, Aldo., Figueredo-Thiel, Susy. Acute toxicity of Xanthium spinosum leaves in BALB/C mice .. Revista peruana de medicina experimental y salud publica, 2016, vol. 33, no. 1, p. 113-9.
Ciucure, Corina Teodora., Sandru, Daniela., Lengyel, Ecaterina., Iancu, Ramona., Tita, Ovidiu. IDENTIFICATION AND QUANTIFICATION OF TANNINS AND ANTHOCYANINS FROM PLANTS WITH BIOACTIVE POTENTIAL . Nano, bio and green - technologies for a sustainable future conference proceedings, sgem 2016, vol i, 2016, p. 575-582.
Babakhodzhaev, A., Kasymov, Sh.Z., Sidyakin, G.P. Xanthatin from Xanthium spinosum. Chemistry of natural compounds, 1975, vol. 9, no. 4, p. 529. DOI
Andreani, Stephane., Paolini, Julien., Costa, Jean., Muselli, Alain. Chemical Composition of Essential Oils of Xanthium spinosum L., an Invasive Species of Corsica. . Chemistry & biodiversity, 2017, vol. 14, no. 1. DOI
Piacente, S., Pizza, C., DeTommasi, N., DeSimone, F. Sesquiterpene and diterpene glycosides from Xanthium spinosum. Phytochemistry, 1996, vol. 41, no. 5, p. 1357-1360. DOI
Ansari, AH., Dubey, KS. 2-Desacetyl-8-epi-xanthumanol-4-O-beta-D-galactopyranoside: The potential antitumour sesquiterpenoidal lactone from Xanthium spinosum bark . Asian journal of chemistry, 2000, vol. 12, no. 2, p. 521-526.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature